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      community The most depressing things about hair loss for me

      in Chat  24 upvotes 5 years ago
      The emotional impact of hair loss and the risks associated with common treatments such as finasteride, dutasteride, minoxidil, RU58841, and Fluridil. People discussed their personal experiences with these treatments, including potential side effects and lowered fertility. Hair transplants were also mentioned as a possible solution.

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 2 years ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  210 upvotes 1 year ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Insane hairline regrowth with natural supps and minox

      in Update  102 upvotes 2 months ago
      A 23-year-old achieved significant hairline regrowth using minoxidil, saw palmetto, collagen peptides, biotin, omega-3, iron, ketoconazole shampoo, and scalp care techniques, without finasteride or dutasteride. The user attributes success to this combination but is unsure which element is most effective.

      community 2 years of dut, 1 year of loss 24m

      in Progress Pictures  519 upvotes 2 months ago
      The user experienced hair regrowth with dutasteride but later lost progress despite using minoxidil foam and dermastamping. Suggestions included reducing dermastamping frequency, conducting blood tests, and considering oral minoxidil or different brands of dutasteride.

      community European finasteride difference

      in Finasteride/Dutasteride  102 upvotes 2 months ago
      Topical finasteride in Europe is often seen as less effective than oral forms, with users suggesting alternative application methods for better results. Many prefer oral finasteride due to cost and effectiveness.

      community When is the cure gonna drop , how much more time

      in Research/Science  112 upvotes 2 months ago
      There is no imminent cure for hair loss, but treatments like Minoxidil, Finasteride, and new drugs such as KX-826, GT-20029, and PP405 are being explored. Current solutions focus on slowing hair loss and stimulating growth, with hopes for better options in the future.

      community Do you think oral minoxidil will become the standard for hair loss in 2026?

      in Minoxidil  141 upvotes 3 months ago
      Oral minoxidil is considered more convenient and effective for some users, with positive results reported, but concerns about side effects and availability persist. Finasteride remains a standard treatment, while some users explore combinations with other treatments like dutasteride and laser devices.

      community From 21 to 23 years old. What do you think?

      in Treatment  331 upvotes 3 months ago
      A user is using oral finasteride, oral dutasteride, and drinking topical minoxidil for hair loss, despite health warnings. Switching from finasteride to dutasteride did not improve hair density.

      community Homelessess: the solution right in front of our eyes?

      in Satire  142 upvotes 4 months ago
      Homelessness is humorously proposed as a solution to hair loss due to less grooming and stress. Treatments like Minoxidil and Finasteride are discussed, with genetics and lifestyle also considered important factors.

      community I’m considering stopping finasteride

      in Finasteride/Dutasteride  157 upvotes 4 months ago
      The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

      community Haircafe video on Min Sulfate, thoughts?

      in Research/Science  101 upvotes 6 months ago
      Minoxidil sulfate is considered for those unresponsive to regular minoxidil, with some trying a 10% formulation from Folligenz. Concerns exist about the product's stability and transparency, but some users report positive initial results.

      community Can we get a reality check on PP405?

      in Research/Science  80 upvotes 6 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community 200 days on dut + min, what do you think?

      in Is this regrowth?  602 upvotes 7 months ago
      The user reports significant hair regrowth after 200 days using dutasteride and minoxidil, attributing changes to hair dye. Others doubt the authenticity and discuss treatment effectiveness and side effects.

      community One year 2.5mg Minoxidil 1.25mg finasteride

      in Progress Pictures  185 upvotes 7 months ago
      A user shared progress pictures after one year of using 2.5mg Minoxidil and 1.25mg Finasteride for hair loss. The discussion includes suggestions for additional treatments like dermastamping, dutasteride, and increasing Minoxidil dosage, with mixed opinions on the effectiveness of current treatments.