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Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

A 23-year-old male has been using oral dutasteride and minoxidil for 1.5 years for temple recession, adding topical minoxidil and tretinoin 5-6 months ago, and recently adjusted thyroid medication and added iron supplements due to deficiencies. He noticed some baby hairs but no significant growth yet, and reports no shedding on dutasteride.

The user reported significant hair regrowth and stopped hair loss after using Pyrilutamide and Minoxidil for four months. They found Pyrilutamide effective in blocking DHT locally without side effects, preferring a gray market version over Koshine's product.

A 20-year-old is considering switching from applying a Minoxidil 5%/Finasteride 0.1% solution twice daily to once daily due to cost and convenience. It is suggested that applying once a day before sleep should still be effective if done consistently.

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

The user has been using finasteride for 3 years with good results and wants to switch to dutasteride combined with tamsulosin. They are seeking more information about tamsulosin.

The user is considering adding topical dutasteride and increasing their oral minoxidil dose to 5mg, and is currently using oral finasteride, oral and topical minoxidil, derma stamping, tretinoin, and nizoral as part of their hair loss treatment regimen.

The user applied 5% minoxidil twice daily and microneedled approximately 1.5 times a month. They noticed some progress in hair growth, though they were unsure if it was due to treatment or hair length.

Combining 0.5 mg oral finasteride with topical finasteride and minoxidil during an Enclomiphene cycle may help manage increased DHT levels. Monitoring for side effects is advised.

Dutasteride at 0.5 mg and 2.5 mg doses may eventually yield similar hair growth results over time, with 0.5 mg being sufficient for many users. Higher doses may not significantly increase benefits and could lead to diminished returns.

A 19-year-old is considering whether to continue finasteride at 0.5mg every other day due to concerns about side effects. They are seeking advice on dosage frequency and potential side effects, noting no issues so far.

The user has been using finasteride and minoxidil for 5 years to prevent hair loss and is considering adding dutasteride for regrowth or opting for a hair transplant. Suggestions include trying dutasteride, oral minoxidil, microneedling, and possibly a hair transplant for better results.

The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.

The user has been using 1.25 mg of finasteride daily since June 2024 to promote hair regrowth and thickness, considering switching to dutasteride if results are unsatisfactory. They are hesitant to add minoxidil due to cost and potential side effects but have seen some progress with finasteride alone.

After switching from finasteride to 0.5 mg dutasteride daily, the user experienced thinner hair but no shedding. They are considering continuing dutasteride and possibly using oral minoxidil, while also dealing with allergy-like symptoms possibly unrelated to the medication.

The user shared progress pictures after using finasteride, minoxidil, and ketoconazole for a year, then switching to dutasteride two months ago. Commenters noted significant improvement in appearance and appreciated the watermark for image protection.

An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.

The user is concerned about the interaction between dutasteride and ketoconazole, leading them to stop using ketoconazole shampoo, which has resulted in an oily and painful scalp. They are unsure whether ketoconazole increases or decreases the potency of dutasteride.

The user is increasing their oral minoxidil dosage from 2.5mg to 5mg after using 1mg finasteride and topical minoxidil foam for over three years without desired results. They have also been microneedling and using tretinoin cream, recently increasing the tretinoin dosage to 0.1%.

Topical finasteride is currently more effective than pyrilutamide for hair loss. Combining treatments like topical finasteride and pyrilutamide may enhance results due to different mechanisms.

HairCarePls shared their 5-month Dutasteride update, mentioning previous use of Finasteride with no results. They also use Spironolactone, Minoxidil, dermarolling, Ketoconazole shampoo, and Yaz contraception for hair loss treatment.

The user shared a 3-month update on using a 5% minoxidil and finasteride topical solution enriched with redensyl and procapil for hair regrowth. They mentioned inconsistency in using the treatment and initially starting it without consulting a dermatologist.

Combining finasteride with dutasteride may have additive benefits for reducing scalp DHT, but the extent is unknown. Some users report less shedding when using both treatments, with variations in dosage and application methods.

Alfatradiol (0.025%) is an effective and safe treatment for androgenetic alopecia in both men and women, increasing anagen hair rates with minimal side effects. Users discuss its cost-effectiveness and ease of use compared to other treatments like finasteride and RU58841, with some combining it with stemoxydine and Minoxidil.

Treatment for hair loss, including Pyrilutamide, Minoxidil, Finasteride, and RU58841; with some users reporting success in growing vellus hairs.

User shared a 1-year update on finasteride, noting thicker hair but mild side effects like reduced libido and mild ED. Considering reducing the dose from 1mg to 0.5mg daily to alleviate side effects.

The user experienced some hair regrowth using twice daily topical 5% minoxidil and once daily oral 1mg finasteride, along with dermarolling. They plan to continue this regimen for at least two years and may try additional treatments if needed.

A 28-year-old male shares progress using 5mg Minoxidil and 0.5mg Dutasteride for hair growth, encouraging the use of these treatments. Users discuss side effects like increased facial hair and debate the effectiveness of treatments within three months.

A dermatologist prescribed 0.5 mg dutasteride and 2.5 mg minoxidil for hair thinning, which is considered a solid regimen for regrowth. Users generally agree that dutasteride is more effective than finasteride and support the dermatologist's decision.

Using RU58841 and topical minoxidil together is fine and does not cancel out the benefits of each. Applying both treatments consecutively is acceptable.