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      community Does DHT Cause Complete Baldness?

      in Research/Science  5 upvotes 8 months ago
      Hair cloning technology is advancing, with clinical trials for improved methods expected by 2028 and 2029, potentially offering a solution for hair loss if donor follicles remain. Organtech's expansion into other biotech areas may secure funding, but the effectiveness of cloning depends on the availability of androgen-resistant donor follicles.

      community Pattern hair loss could be due to gut bacteria

       53 upvotes 6 years ago
      Feeding bacteria-free mice with Lactobacillus murinus worsened hair loss, but a regular diet with biotin stopped it. The conversation suggests gut bacteria and diet may influence hair loss, with some skepticism and discussion about other factors like DHT and genetics.

      community Well… I Did It. Estrogen Saved My Hairline

      in Transgender  735 upvotes 1 year ago
      OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

      in Transgender  2267 upvotes 9 months ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

      community Transformation dut+min 8months

      in Is this regrowth?  15 upvotes 4 months ago
      The user switched from finasteride and topical minoxidil to dutasteride, oral minoxidil, and topical minoxidil for 8 months, resulting in hair regrowth. Some users suggest dropping the topical minoxidil.

      community Switch to Dut??

      in Finasteride/Dutasteride  9 upvotes 6 years ago
      Considering a switch from finasteride to dutasteride for hair loss treatment, and the use of minoxidil as a last resort due to its effects on hair texture.

      community Duality of (diffuse thinning) man

      in Chat  67 upvotes 1 year ago
      The user has been using finasteride for over two years with mixed results and is considering starting dutasteride and oral minoxidil, though both are hard to obtain. They are also contemplating a hair transplant in the future due to diffuse thinning.

      community How to tell if it’s miniaturizing vs regrowth?

      in Is this regrowth?  9 upvotes 9 months ago
      The conversation discusses hair regrowth and miniaturization, with the user transitioning to oral dutasteride and oral minoxidil, and occasionally using topical minoxidil. The user observes baby hairs near the hairline but less on the scalp, indicating possible regrowth and shedding.

      community ghk-cu is potent 5-ar inhibitor?

      in Product  9 upvotes 2 years ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2450 upvotes 5 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Nuclear Stack Ineffective: Oral DUT/FIN/MIN/RU - NAFLD?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.

      community Hormone tests to decide on oral fin

      in Finasteride/Dutasteride  4 upvotes 10 months ago
      The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.

      community Is this finally regrowth at my temples?!

      in Is this regrowth?  16 upvotes 5 months ago
      The user switched from topical to oral finasteride and minoxidil, noticing thicker and longer baby hairs, suggesting potential regrowth at the temples. Other users agree it looks like a sign of success.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  16 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community Insane MTF recovery 18 months blocking androgens

      in Progress Pictures  145 upvotes 3 years ago
      Hair loss recovery using estrogen and anti-androgen treatment for 18 months showed significant improvement. However, results vary and alternative treatments like RU58841 and Dutasteride may work without systemic feminization.

      community PP405 - hair stem cell stimulation

      in Research/Science  49 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.