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      104 days of .5mg dut at 17 (read desc)

      community 104 days of .5mg dut at 17 (read desc)

      in Journals / Progress Pictures  81 upvotes 9 months ago
      The user has been using oral Dutasteride (.5mg) for 104 days and oral Minoxidil (.5mg) for about 2 months to address hair loss. Changes in hair appearance are noted, influenced by haircuts and dyeing, which affect the visibility of thinning areas.

      community Pyrilutamide bulk powder purchasing

      in Product  2 upvotes 1 year ago
      Pyrilutamide is being used effectively for hair loss with no side effects, and the user is seeking a cheaper bulk supplier. Users discuss the difficulty of finding affordable, trustworthy sources, with some suggesting potential suppliers.

      community Dutasteride shedding starts at month 4?

      in Treatments  66 upvotes 9 months ago
      Dutasteride can cause hair shedding, which may start around the fourth month of treatment. The user is concerned about whether this shedding is due to the medication or the progression of hair loss.

      community Update: Chest discomfort from RU58841

      in Update  34 upvotes 2 years ago
      A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Dutasteride and elevated (LDL) cholesterol

      in Finasteride/Dutasteride  1 upvotes 11 months ago
      The user switched from finasteride to dutasteride for hair loss and noticed elevated cholesterol levels, questioning if dutasteride caused this change. They also take Vitamin D, biotin, magnesium, ginkgo biloba, omega-3, and NAC, and are concerned about the impact of these supplements and their health on cholesterol levels.

      community Huge holes on donor area of scalp is this even normal?

      in Transplants  106 upvotes 2 years ago
      The conversation is about a person experiencing significant hair loss in the donor area after a hair transplant, with others suggesting it might be shock loss. The person is taking oral minoxidil and dutasteride to help with the issue.

      community Questions about DUPA and figuring out what my hairloss is (NEED INPUT BADLY)

      in Finasteride/Dutasteride  5 upvotes 11 months ago
      The conversation discusses severe hair shedding and thinning, with the original poster using finasteride, oral minoxidil, and other supplements without improvement. The discussion highlights the possibility of telogen effluvium and the importance of addressing potential underlying health issues, such as stress and gut health, rather than assuming diffuse unpatterned alopecia (DUPA).

      community Update: .5mg Dut, Min 5% foam, Olly hair gummies- all daily

      in Progress Pictures  67 upvotes 4 months ago
      The user reports progress in hair regrowth using a daily routine of 0.5mg Dutasteride, 5% Minoxidil foam, and Olly hair gummies, while discontinuing rosemary water. They are hopeful for continued improvement and have received positive feedback on their progress.

      community Request for advice, feedback...

      in Chat  2 upvotes 10 months ago
      The conversation discusses hair loss treatments for a woman experiencing androgenetic alopecia and seborrheic dermatitis, with suggestions including low-dose oral minoxidil, dutasteride, and hormone replacement therapy. The user is seeking advice due to intolerance to spironolactone and topical minoxidil, and concerns about low testosterone and DHT levels.

      community KX-826 (Pyrilutamide) on Amazon

      in Treatment  9 upvotes 1 year ago
      The conversation is about purchasing KX-826 (Pyrilutamide) on Amazon, now called Koshine. A user mentioned their order is expected to arrive between August 22 and September 13.

      community PYRILUTAMIDE KX-826 experience

      in Research/Science  101 upvotes 3 years ago
      A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.

      community CAUTION: My Experience with RU58841

      in Treatment  13 upvotes 2 years ago
      The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 7 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community Binding affinity of pyrilutamide!

      in Update  169 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Is DUT better or worse than FIN?

      in Finasteride/Dutasteride  62 upvotes 2 years ago
      The conversation discusses the effectiveness of Dutasteride (DUT) and Finasteride (FIN) for hair loss. Users share varied experiences, with some finding DUT more effective and others experiencing side effects or no change, highlighting that individual responses can vary.

      community Washing hair every day instead of a couple times a week

      in Treatment  7 upvotes 4 years ago
      The user discusses the potential impact of external DHT in sebum on hair loss and plans to wash their hair daily with salicylic acid exfoliation. They believe this might help reduce hair loss despite internal factors.

      community Thoughts on this 2-deoxy-D-ribose Topical?

      in Treatment  25 upvotes 1 year ago
      The post and conversation are about skepticism towards a new hair loss treatment containing 2-deoxy-D-ribose, copper peptides, and exosomes, with concerns about the legitimacy of the product and its website. The treatment's effectiveness and authenticity are questioned due to lack of testing and transparency.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Has anyone switched from topical fin to dut?

      in Finasteride/Dutasteride  12 upvotes 10 months ago
      The conversation discusses switching from finasteride to dutasteride due to side effects, with some users experiencing fewer side effects on dutasteride. It also mentions using liposomal topical finasteride and ketoconazole shampoo as alternative treatments.

      community I think I gave myself congestive heart failure

      in Minoxidil  6 upvotes 5 years ago
      A user experienced severe side effects, including symptoms of congestive heart failure, after using excessive doses of minoxidil for beard growth. They stopped using it due to financial reasons, but still suffer from lingering symptoms and are advised to seek medical attention.

      community [Diary] [Day 150?] Dutasteride every day still failing to help

       4 upvotes 9 years ago
      A 22-year-old is experiencing hair thinning despite using finasteride and dutasteride, and plans to try minoxidil next. The user is frustrated with the lack of results and is considering drastic measures if the situation doesn't improve.