PP405 shows promise for hair follicle reactivation with minimal side effects. Users recommend continuing Minoxidil and Finasteride until more results are confirmed.
A user is seeking advice on ordering ethanol in the UK to use with topical finasteride, considering switching from isopropyl alcohol. They mention the possibility of purchasing 99.8% ethanol from eBay's 6 Science shop.
ET-02 showed significant hair growth in five weeks, outperforming minoxidil, with a non-hormonal mechanism that avoids side effects of treatments like finasteride. A phase 2 trial is planned to further assess ET-02's efficacy and safety.
PP405 is expected to be on the market between 2027 and 2030, with phase 3 trials starting in 2026. There is skepticism about its fast-tracking due to its cosmetic nature, and it may appear on the gray market sooner.
A user shared their 9-month progress using RU58841 at 2% daily for hair regrowth, initially starting at 5% but reducing the dose due to early signs of gynecomastia, which has since mostly resolved. They achieved their goal of regrowing hair at the temples and hairline.
A user seeks advice on mixing RU58841 serum using European ingredients, specifically struggling to find propylene glycol. They are looking for alternatives to American products commonly recommended in guides.
The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.
PP405's effectiveness in increasing hair density is questioned due to a small sample size, despite investment from Google Ventures. Users express skepticism and suggest waiting for more conclusive results.
The conversation discusses using a 0.1% topical finasteride solution twice daily after experiencing brain fog from oral finasteride. A user suggests trying the solution once daily for a few months if concerned.
Hope Medicine's HMI-115 is expected to be released in 2027, with phase 3 trials currently recruiting. Concerns include the safety of targeting prolactin and the potential cost of the treatment.
A user is seeking advice on creating a Minoxidil-free topical Finasteride solution due to side effects and concerns about pets. They plan to use Isopropanol alcohol, Propylene Glycol, and distilled water to make a 0.02% solution, starting with 1ml applications.
Redensyl, Capixyl, and Procapil combined are compared to 5% Minoxidil for treating hair loss. The discussion focuses on the effectiveness of these treatments.
A user's successful hair loss treatment using ketoconazole shampoo, 0.5mg finasteride, and 5% liquid minoxidil. They noticed significant results after 4 months, with reduced hair fall observed earlier.
Using a microdose of finasteride on the scalp with minoxidil as a carrier may have positive effects with minimal side effects. The user is also considering the effects of sulforaphane or broccoli sprouts on hair loss.
PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.
HMI-115 is a new drug developed by Bioinvent and licensed by Bayer, with mixed opinions on its potential effectiveness. Some users are skeptical and prefer proven treatments like Minoxidil, finasteride, and RU58841.
The conversation is about the use and application of CB-03-01-2 (Breezula) for hair loss, including questions about its form, how to apply it, and the duration 10g would last. Specific treatments discussed are Minoxidil, finasteride, and RU58841.
Stemoxydine is more expensive than minoxidil and finasteride, costing $50-$150 per month. The discussion questions why the cost is higher despite efficacy.
A user discussed their doctor lowering their Minoxidil dose from 5mg to 2.5mg, expressing concerns about losing hair gains. Other users suggested that 2.5mg is safer long-term and speculated the doctor is being cautious about side effects.
ScottMills3 shared how to quickly get a prescription for generic Dutasteride (Dut .5mg) online through MedicalWellnessCenter, which cost $69.95 for the consultation and $31 for a 90-day supply. Another user suggested hidrb.com as a cheaper alternative, offering the same prescription for $15.
The conversation is about a user who experienced significant hair recovery using 5% Minoxidil and 0.1% Finasteride, specifically with the Traya brand. The user emphasizes consistency and early treatment for effective results, noting improvements in hair volume and some side effects like dry scalp.
A man shared his 6-month hair regrowth progress using 0.5mg of finasteride daily and recently increased the dose to 1mg. Users discussed the effectiveness of the treatment and shared their own experiences with hair loss treatments.
A user shared progress pictures showing successful hair retention using a low-dose topical finasteride (0.008%) combined with minoxidil. Users discussed the effectiveness of the treatment, minimal effective dosing, and avoiding systemic side effects.
The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.
The conversation discusses whether 2.5mg of dutasteride or 200mg of testosterone weekly is more influential in preventing hair loss, with various personal experiences indicating that the effectiveness is dependent on the individual's genetic profile. Some users report that dutasteride is likely to be more effective at the given doses.
Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.
The conversation discusses the anticipation of Chinese manufacturers producing Clascoterone 5% before its full approval in 2027. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.
The conversation discusses finding a finasteride dosage that reduces DHT by about 25% to minimize side effects, with considerations for topical versus oral formulations. Alternatives like dutasteride mesotherapy and topical treatments are explored, with concerns about systemic absorption and potential impacts on athletic performance and hormone levels.
MaximusDurkimus shares experience with 0.25mg Finasteride, Minoxidil-induced lupus, and less than 10mg RU58841 for hair loss. Plans to try 0.025% topical Finasteride with 5% Stemoxydine and possibly Tretinoin, Fluridil, or CB-03-01 in the future.
The user is applying topical finasteride with stemoxydine for hair loss and has noticed hair thickening but no regrowth after two months. They also report high SHBG and prolactin levels and a lack of morning erections, even on low doses of medication.