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      community KX-826 , a small change in the pipeline

      in Research/Science  6 upvotes 2 months ago
      KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

      community How to deal with mechanically induced shedding

      in Minoxidil  5 upvotes 6 months ago
      Minoxidil can cause scalp dryness and flaking, leading to hair shedding when exfoliating. Alternatives like oral Minoxidil, finasteride, and ketoconazole shampoo are suggested to manage these issues.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 7 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Dandruff and Topical Solutions

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      The user is using a topical solution with finasteride, minoxidil, and retinoic acid, which causes scalp residue and dryness. They seek advice on removing residue and keeping the scalp moisturized.

      community Extreme shedding after ~1 year on 5% topical minoxidil — normal or problem?

      in Minoxidil  4 upvotes 2 months ago
      A 17-year-old using 5% topical minoxidil experienced significant hair shedding after a year, possibly due to a "synchronization shed" and deficiencies in vitamin D and iron. Recommendations include continuing minoxidil, optimizing vitamin D and iron levels, and reducing tretinoin use if scalp irritation occurs.

      community Brief update clascoterone phase 3 - Breezula

      in Research/Science  4 upvotes 2 years ago
      Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

      community KX-826. What have been your experiences?

      in Product  1 upvotes 2 weeks ago
      KX-826 may cause increased hair loss for some users, leading to concerns about its effects. One user reported no issues but also no hair regrowth, only maintenance.

      community Stopping min on scalp - psoriasis

      in Minoxidil  35 upvotes 1 year ago
      A user with mild psoriasis on the scalp is using finasteride, topical minoxidil, and dermarolling for hair loss but plans to stop minoxidil on the crown due to psoriasis aggravation. Suggestions include switching to a lipid-based minoxidil, using Ketoconazole shampoo, or trying oral minoxidil.

      community CRAZY HIGH? 1% Fin 0.3% GHK-CU topical perscription

      in Treatment  2 upvotes 1 month ago
      The conversation discusses concerns about using a high concentration of 1% topical finasteride for hairline balding, with some users suggesting starting with a lower dose. It also mentions the use of GHK-CU peptide and the importance of considering the formulation to avoid excessive absorption.

      community Can hard water affect your scalp/hair?

      in Chat  15 upvotes 4 years ago
      Hard water may contribute to an itchy, dry scalp and hair issues, but it doesn't affect genetic hair loss. Some users suggest using distilled water or a water softener to alleviate symptoms.

      community Do exosomes actually work to regrow hair?

      in Treatment  8 upvotes 8 months ago
      Microneedling with exosomes is being considered for hair regrowth, but concerns exist about their effectiveness and safety, especially since exosomes degrade quickly and lack FDA approval. The user is seeking alternatives for non-responders to minoxidil and dutasteride, as exosomes may not provide additional benefits.

      community How effective is spironolactone?

      in Transgender  5 upvotes 3 years ago
      A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hair loss, despite being aware of its serious side effects.

      community How I started reversing Male Pattern Baldness naturally ?

      in Question  7 upvotes 9 years ago
      The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

      community My current nuclear stack. Thoughts?

      in Chat  6 upvotes 2 years ago
      The user is using RU58841 twice daily, dutasteride 0.5mg every two days, dutasteride mesotherapy every three months, and 20mg oral minoxidil daily. Other users suggest this regimen is excessive and recommend adding microneedling and ketoconazole shampoo.

      community Any clinical study on cysteine alone for hair loss?

      in Research/Science  6 upvotes 1 year ago
      The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.

      community Ketoconazole mesotherapy plausible?

      in Ketoconazole  10 upvotes 1 year ago
      The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.

      community Has anyone seen the data on this 539% boost breakthrough?

      in Technology  872 upvotes 1 month ago
      Topical Clascoterone showed a 539% improvement in hair count compared to placebo, but its effectiveness and safety are debated. Users compared it to minoxidil and finasteride, with mixed opinions on its potential release in 2026 or 2027.

      community Ketoconazole shampoo with a brush

      in Ketoconazole  1 upvotes 1 year ago
      Using a silicone shampoo brush with ketoconazole shampoo may increase hair shedding if used roughly. Hair that sheds during shampooing would have fallen out eventually.