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      community Dr. Kyle Gillet on Dr. Andrew Huberman's podcast said dutasteride mesotherapy blocks DHT conversion only in the scalp and called it the most promising topical currently. What's the scoop?

      in Treatment  24 upvotes 4 years ago
      Dr. Kyle Gillet mentioned on Dr. Andrew Huberman's podcast that dutasteride mesotherapy blocks DHT conversion only in the scalp and is the most promising topical treatment. Users discussed concerns about systemic absorption and the practicality of dutasteride injections.

      community PSA: Greasy, product laden hair makes the scalp 10x more visible

      in Treatment  30 upvotes 1 year ago
      Greasy or product-laden hair can make the scalp appear more visible, leading some to mistakenly think they are balding. Proper hair washing and avoiding heavy products can help assess true hair thickness, and treatments like finasteride are used by some for actual hair loss.

      community 33M Medication w/scalp psoriasis

      in Progress Pictures  1 upvotes 1 month ago
      A 33-year-old male restarted finasteride after stopping it to conceive, noticing hair loss, especially in the crown area. His current routine includes finasteride, minoxidil, ketoconazole, and microneedling, and he plans to continue this treatment for 18 months before making any major changes.

      community Female androgenetic alopecia (w/ PCOS) starting treatment

      in Female  4 upvotes 1 year ago
      A female with PCOS and androgenetic alopecia is starting treatment with oral Minoxidil, topical Minoxidil 5% with finasteride, and plans to add mesotherapy. She previously tried anti-androgenic contraceptive pills but couldn't tolerate them and is using Myo Inositol for weight management.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community Experiences with topical Finasteride (0.0125%)?

      in Finasteride/Dutasteride  7 upvotes 10 months ago
      A 23-year-old male with slight hair thinning is using ketoconazole shampoo, biotin, zinc, magnesium, D3/K2, and has just started topical finasteride (0.0125%). He plans to add minoxidil (4.5%) with 17α-estradiol and is seeking advice on the effectiveness and side effects of these treatments, as well as the use of a dermaroller.

      community Reputable place to buy Clascoterone?

      in Product  2 upvotes 2 months ago
      The conversation is about finding a reputable place to buy Clascoterone in the US. An alternative treatment, pyrilutamide, is suggested as a strong and official option.
      Is my hair loss from itching/shampoo or am I just balding?

      community Is my hair loss from itching/shampoo or am I just balding?

      in General  84 upvotes 11 months ago
      A 28-year-old male is experiencing hair loss, possibly due to seborrheic dermatitis, itchiness, or shampoo use, and is considering treatments other than minoxidil or finasteride. He plans to consult a doctor for further advice.

      community Topical melatonin/cetirizine instructions

      in Treatment  19 upvotes 3 years ago
      User shares a topical hair loss solution using melatonin and cetirizine to help reduce shedding and itching. Instructions provided for creating and using the mixture, with additional lifestyle tips for overall hair health.

      community Head itch even though I use keto shampoo

      in Ketoconazole  3 upvotes 1 year ago
      The user experiences scalp itchiness despite using ketoconazole shampoo and is also taking oral finasteride and minoxidil. Suggestions include trying different shampoos like Head & Shoulders, using salicylic acid products, considering allergies, and consulting a dermatologist for alternatives like Ciclopirox.

      community Itchy scalp with fin/min - what should i do?

      in General  30 upvotes 1 year ago
      The user started using 0.1% finasteride and 5% minoxidil twice daily and experienced an itchy scalp. Suggestions include checking for allergies, dry scalp, or seborrheic dermatitis.

      community My DHT-blocking protocol, I'm exited!

       6 upvotes 6 years ago
      The post discusses a hair loss treatment regimen using saw palmetto, pumpkin seed oil extract, EGCG (green tea) extract, grape seed oil extract, rosemary oil extract, and Zix. The user plans to use these DHT-blockers and 5AR inhibitors for six months and report the results.

      community How did you all stop the itching that occurs where you are balding?

      in Treatment  17 upvotes 1 year ago
      People discussed solutions for scalp itching related to hair loss, with treatments including finasteride, dutasteride, ketoconazole shampoo, and Alpecin Hybrid shampoo. Some users found relief by adjusting dosages of finasteride or switching to dutasteride, while others recommended specific shampoos or prescription options like olux foam.

      community Recent discovered thinning hair, taking steps to diagnose.

      in Chat  2 upvotes 7 months ago
      A 43-year-old noticed significant hair thinning and is using topical minoxidil, dermarolling, Alpecin, biotin, zinc, copper, vitamin D, and rosemary oil. They plan to see an endocrinologist and have blood tests scheduled to investigate further.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Can topicals cause a never ending shed?

      in Treatment  2 upvotes 2 years ago
      The user reintroduced RU58841 and noticed increased shedding and visible thinning. They have also been using dutasteride and oral minoxidil for 2 years.

      community Improvement or Delusional? 21M

      in Is this regrowth?  4 upvotes 1 year ago
      A user is using topical finasteride, keto shampoo, microneedling, and tretinoin for hair loss and is considering adding pyrilutamide. They notice some improvement at the temples and seek advice on whether to focus on cosmetic results despite daily shedding.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  14 upvotes 3 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Anger and frustration as I finally learn my diagnosis.

      in Female  6 upvotes 2 years ago
      A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

      community For those of you applying Pyrilutamide, what's your plan B?

      in Treatment  6 upvotes 2 years ago
      The user switched from Pyrilutamide to RU58841, changed their Minoxidil solution, and continued using low-dose Finasteride, derma rolling, and specific shampoo. They asked others about their plans after Pyrilutamide's disappointing results.

      community ~3 year update on my singular DHT immune hair for you guys

      in Update  20 upvotes 2 years ago
      The post is an update on the user's hair loss journey. They have a strong hair follicle that has remained unaffected by hair loss for almost 3 years. The user is starting finasteride and using ketoconazole, alfatradiol, and oral castor oil for hair maintenance.