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      community Rate my stack! (Using a nuclear protocol)

      in Finasteride/Dutasteride  16 upvotes 5 years ago
      A hair loss regimen involving Dutasteride, Oral Minoxidil, Mesotherapy, Topical Minoxidil/Finasteride, RU58841, Alfatridiol, Microneedling, LLLT, Keto shampoo, Vitamin K/D/Fish oil/Borage Oil/MSM, Oral Castor oil and Niacin. It also mentions products that have been dropped from the regimen due to not being worth the hassle or messing with libido.

      community Don't use PP405 from everychem. it is likely fake.

      in Research/Science  65 upvotes 9 months ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community I wish I were a man so bad. Life is cruel

      in Female  226 upvotes 1 month ago
      A woman with androgenetic alopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.

      community DUT Risk profile for having kids?

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.

      community Do you know any alternative to Minoxidil ?

      in Minoxidil  2 upvotes 6 months ago
      The user experienced side effects from oral minoxidil and is seeking alternatives like Stemoxydine, Aminexil, and Redensyl + Procapil. They have been using finasteride for four years and are considering other treatments due to concerns about side effects.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Oxytocin, empathy, hair, and cinnamon

      in General  138 upvotes 1 year ago
      Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.

      community (17M) Hair loss and Cystic Acnes / Dutasteride

      in Finasteride  109 upvotes 4 months ago
      A 17-year-old is using Finasteride and Minoxidil for hair loss, experiencing hair shedding and cystic acne. They are considering Dutasteride for acne but are concerned about potential side effects on genital development.

      community Topical Finasteride - Affordable options

      in Finasteride/Dutasteride  4 upvotes 6 years ago
      The conversation discusses affordable options for topical Finasteride, including products like Morr F, 82F, and Essengen 6 Plus, with concerns about availability and cost. The user is seeking effective and convenient solutions, considering options like compounding pharmacies and homemade solutions.

      community Trans: Do I need to use Finnasteride?

      in Transgender 2 years ago
      A transgender individual is starting spironolactone and estradiol for hormone replacement therapy (HRT) and is considering adding finasteride to help with hair loss. They are also planning to use minoxidil and microneedle, but are unsure if they need to use another anti-androgen or more aggressive treatments. A respondent advises against using pyri and suggests waiting to see if the HRT alone is sufficient before becoming dependent on minoxidil.

      community New Study - Flavonoids More Effective Than Finasteride?

      in Research/Science  148 upvotes 2 years ago
      A recent publication suggests that the flavonoids eriocitrin and silymarin may be more effective than finasteride in binding to the enzyme responsible for hair loss. People in the conversation are skeptical about the effectiveness and safety of these flavonoids until tested on humans, and some discuss their personal experiences with other treatments.

      community 8 months of 1mg fin EOD and 1ml of topical min ED

      in Progress Pictures  185 upvotes 1 year ago
      The user experienced significant hair regrowth using 1mg finasteride every other day and 1ml topical minoxidil daily, with initial shedding but improvement by three months. Microneedling was also used, with adjustments to frequency and needle length for better results.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 6 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

      community I posted once before in this sub about my struggle to get a script for a DHT blocker other than Spironolactone, here’s visual evidence that I am in fact biologically female. How bad is it, lads

      in Female  6 upvotes 3 years ago
      The conversation is about a female's difficulty in obtaining a prescription for a DHT blocker other than Spironolactone for hair loss. She is seeking advice on the severity of her condition and discussing specific treatments like Minoxidil, Finasteride, and RU58841.

      community Guide To Finasteride and Avoiding Side Effects

      in Finasteride/Dutasteride  26 upvotes 3 years ago
      The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

      community Reasonable and safe stack? Bloodwork within.

      in Minoxidil  1 upvotes 2 years ago
      A 26-year-old male is using a combination of clomiphene, minoxidil, tadalafil, bupropion, and lisdexamfetamine to address low testosterone, ED, depression, and focus issues. He seeks input on the safety and efficacy of this regimen, which also includes magnesium, zinc, and fish oil supplements.

      community progress pics (HRT, fin, min, microneedling) (35, trans non-binary)

      in Transgender  10 upvotes 1 year ago
      A non-binary transfeminine person experienced significant hair regrowth after starting finasteride, minoxidil, microneedling, and hormone replacement therapy with estradiol. They encourage trans individuals concerned about hair loss to consider estrogen as it has greatly improved their hair condition.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 2 years ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.