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690-720 / 1000+ resultscommunity How can ru-58841 be effective if pyrilutamide failed phase 3 clinical trials?
The conversation discusses the effectiveness of RU58841 for hair loss compared to pyrilutamide, which failed to show significant hair regrowth in trials. Some users report personal side effects with RU58841 and question the criteria for success in hair loss treatments.
community Has anyone had experience with 1mg + of dut?
A user is asking about increasing their dutasteride dosage from 0.5mg to up to 2.5mg and whether it improves hair loss treatment. They are seeking experiences from others who have tried higher doses.
community Dut increase dose after year of no progress?
The user has been on dutasteride and oral minoxidil for a year with no progress and is considering increasing the dutasteride dose or adding RU58841. Other users suggest consulting a doctor, trying derma needling with topical minoxidil, and note that hair loss treatments can have varying effectiveness.
community DS Labs SOD suppliments, anyone try them?
The conversation is about trying DS Labs SOD supplements for hair loss, which contain ingredients like Genistein, B-sitosterol, and Biotin. The user is considering adding these supplements to their existing hair care routine.
community cheers too 2 months of min and dut (i also use like 30 diff things)
The conversation is about someone experiencing hair regrowth using Minoxidil and Dutasteride, along with other treatments. They report their hairline is improving and their forehead appears smaller.
community Megadosing Koshine826(Pyrilutamide), my Plan.
The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.
community Where is GT20029 already? Grrrr
The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.
community Has any had the Regenera Activa treatment?
community RU58841 Users: How chemically unstable is RU58841 in practice?
The conversation discusses using RU58841 mixed with topical minoxidil for hair loss, noting its chemical instability and storage challenges. A user shares their experience using RU58841 with ethanol and propylene glycol, mentioning no significant results yet.
community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry
Hair loss discussion mentions using estrogen mixed with growth stimulants like oral minoxidil for scalp hair growth. Idea proposed for an artificial SARM-estrogen that only affects hair without body side effects.
community 10 month progress - Dut, topical min, 1.5mm roller
The conversation is about hair loss progress using treatments such as Dutasteride, topical minoxidil, and a 1.5mm roller.
community Amplifica and AMP-303 clinical phase 1
Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.
community 25M (2.5mg Oral Min + 1mg Oral Fin Daily)
community TRT. Pyrilutamide. Ru58841. Help
A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.
community Today situation. 7 months Dutas, oral min and 2 days on ru58841 (last photo is progress)
The conversation discusses hair loss treatment progress over 7 months using Dutasteride, oral Minoxidil, and recently started RU58841. The last photo shows the progress made with these treatments.
community Seb derm & ru: after quitting ru for a week after 2+ years of use, my scalp is itching a lot less
Quitting RU58841 after over two years reduced scalp itching and inflammation, despite concerns about losing hair gains. The user continues using finasteride and oral minoxidil.
community 6 years oral minoxidil 5mg, dut 0.5 everyday, dermarolling 2.5 weeks 1.5mm
community 36yo male, NW6, 2.5mth dut/minox
A 36-year-old male using dutasteride and minoxidil has seen significant hair regrowth, confirmed by a dermatologist and supported by before-and-after photos. He plans to increase his oral minoxidil dosage and add dermapen to his routine.
community RU58841 and impact onmale fertility?
The conversation is about the potential impact of RU58841 on male fertility, specifically regarding sperm concentration, total count, and motility. The user is curious about the likelihood of RU58841 reducing fertility based on its mechanism of action and comparisons to similar substances.
community What’s the consensus on RU58841 vs Pyrilutamide (Kx-826)?
RU58841 and Pyrilutamide (Kx-826) are both topical anti-androgens, but neither is effective for hair regrowth. RU58841 has more anecdotal support, while Pyrilutamide has progressed further in trials, though both have limitations.
community Eucapil is my savior - Significant reduction in hair loss (with pictures)
User ItchyRaccoon experienced significant hair loss reduction using Eucapil after trying low-dose topical finasteride with no results. Some replies mention that shed hair counts are not reliable indicators of hair loss progression or regression.
community Is this legitimate dutasteride?
community Feel like im not making process. Had insane shed. (Min/Fin/HRT)
The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.
community RU58841 for 10 months- no results. Anyone else?
RU58841 not working for hair loss after 10 months. Concerns about purity of experimental drugs.
community Chinese Research Chemicals You Suggest
The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.
community Anyone tried switching from RU to Pyrilutamide (KX-826)
The conversation discusses switching from RU58841 to pyrilutamide for hair loss treatment, with users generally recommending staying on RU58841 if it is effective. RU58841 is sourced from GeneTherica, which ships worldwide.
community Epibiotech will now offer off-the-shelf allogeneic hair multiplication treatment in South Korea
Epibiotech will offer off-the-shelf allogeneic hair multiplication treatment in South Korea, using dermal papilla cells from donors to grow hair in balding areas. This method is cheaper and less invasive than traditional hair transplants.
community My update oral min 2.5mg 23months dut 0.5mg EOD 14 months slow proggress
The conversation discusses hair loss treatments, specifically oral minoxidil (2.5mg), dutasteride (0.5mg every other day), and ketoconazole. The user reports slow progress but significant hair growth after adding ketoconazole to their routine.
community How exactly is Eucapil (fluridil) approved in Europe?
Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Eucapil (fluridil) is approved as a cosmetic hair-care agent in Europe, but users question the level of testing required for approval.