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      community Huge hair shedding on Astaxanthin.

      in Treatment  2 upvotes 3 months ago
      Astaxanthin may cause increased hair shedding, affecting even transplanted hair and eyebrows. The user has tried various treatments for androgenic alopecia, including minoxidil, finasteride, and RU58841.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  416 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community The "DHT" itch myth - it's more complicated

      in Product  6 upvotes 3 years ago
      A user found that scalp itch might be linked to inflammation rather than DHT alone and noticed hair improvement with certain cancer drugs. They also discovered that black seed oil relieved their scalp itch and are experimenting with a mix of essential oils for dry scalp, questioning if oils affect minoxidil absorption.

      community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

      in Treatment  44 upvotes 4 years ago
      The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

      community Pyrilutamide just launched internationally, and all you're doing is hating

      in Product 1 year ago
      The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

      community Replacing Microneedling with Lice?

      in Chat  70 upvotes 1 year ago
      Using lice as an alternative to microneedling for hair loss treatment, with concerns about effectiveness and practicality. Some users humorously suggest genetically altering lice to produce beneficial compounds.

      community Shedding from Red Light Therapy ( LLLT )

      in Treatment  1 upvotes 2 years ago
      A 31-year-old uses Minoxidil, RU58841, Reviv Hair Serum, and Ketoconazole shampoo for hair loss but avoids finasteride. They plan to reintroduce red light therapy (LLLT) and Eucapil despite previous shedding concerns.

      community Ru 58841 and essential oils question

      in Treatment  3 upvotes 4 years ago
      The user discusses using essential oils like peppermint, rosemary, tea tree, and lavender to improve hair thickness and seborrheic dermatitis. They plan to add RU58841 to their routine and seek advice on using it alongside the essential oils without interference.

      community Experiences with Eucapil? Itching scalp

      in Treatment  4 upvotes 3 years ago
      User discusses Eucapil for hair loss treatment and asks if it helps with itchy scalp. People share their experiences and results, including maintenance or slight improvement.

      community Has anybody tried RU58841 and pyrilutamide together?

      in Chat  10 upvotes 11 months ago
      RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.

      community Clascoterone (Winlevi) now approved in Canada

      in Product  14 upvotes 3 years ago
      The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

      community Anyone else a non-responder to spiro?

      in Treatments  63 upvotes 2 years ago
      The conversation discusses hair loss treatments, specifically mentioning Spiro, Min, Fin, and RU. It highlights that Spiro is generally for women and can affect men's hormonal balance.

      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 4 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community The 'DHT itch' is real - notes from a casual bodybuilder

      in Chat  115 upvotes 1 year ago
      The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.

      community Where the fuck are the pyrilutamide GB guys?

      in Chat  23 upvotes 4 years ago
      The effects of Pyrilutamide, a hair loss treatment that is being tested for June/July; and reports from people who have experienced side effects similar to those of RU58841, suggesting they may have been sold an incorrect product from their supplier.

      community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

      in Treatment  4 upvotes 1 year ago
      The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.

      community L. reuteri (probiotic for Androgenic Alopecia)

      in Finasteride/Dutasteride  34 upvotes 3 months ago
      L. reuteri, a probiotic, is being explored for its potential benefits in treating androgenic alopecia, possibly enhancing finasteride's effects and reducing inflammation. The user combines this with finasteride, oral minoxidil, and other supplements, noting some improvement in hair loss.

      community Here's why you don't assume you have TE, because you likely don't

      in Chat  47 upvotes 1 year ago
      TE (telogen effluvium) is often misunderstood and is triggered by severe stress or trauma, not minor daily inconveniences. Most hair loss cases are due to male pattern baldness (AGA), and treatments like Minoxidil and finasteride can help.

      community Disappointing news on Breezula/CB-03-01

       22 upvotes 7 years ago
      The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.

      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 1 year ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community Why is there so much negativity around pyrilutamide?

      in Research/Science  19 upvotes 1 year ago
      Pyrilutamide is discussed as an effective hair loss treatment by some users, despite skepticism due to limited data and underwhelming trial results. Users compare it to finasteride, minoxidil, and RU58841, with some expressing interest in its potential as an adjunct treatment.

      community Is itching related to hair loss?

      in Treatment  54 upvotes 3 years ago
      Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.