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community 23M Experiencing Thinning at Crown/Mid Area; Minoxidil for 1 Month, Considering Finasteride
A 23-year-old is experiencing hair thinning at the crown and mid part, possibly due to vaping, and is using minoxidil, derma rolling, PRGF sessions, rosemary oil, ketoconazole shampoo, and vitamin D3 supplements. They are considering adding finasteride but are concerned about its side effects.
community $120 million Series B funding to Pelsge
Pelage Pharmaceuticals received $120 million in Series B funding for hair loss treatment development. The conversation expresses excitement and anticipation for the release and effectiveness of the treatment.
community Dermatch as good or better than Hair Fibres?
Dermmatch is wind and water proof, but requires more hair to look good. Using both Dermmatch and hair fibers together can provide better coverage and a more natural look.
community Stress make you more androgen sensitive
Stress can increase androgen sensitivity, potentially worsening hair loss. Treatments discussed include Minoxidil, finasteride, and RU58841.
community 3.5 months on Minoxidil, Weekly 0.6mm microneedle
A trans woman experiencing male pattern baldness has been using Minoxidil and microneedling for 3.5 months, noticing visible hair regrowth. Despite initial skepticism, progress is evident, though a hair transplant might be needed for fuller coverage.
community How to make topical melatonin?
The conversation is about creating a topical melatonin treatment for hair loss. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.
community Topical melatonin/oral
The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.
community 137 years old and still far more hair than the average r/tressless user
The post and conversation are about a user claiming to be 137 years old with a full head of hair. Specific treatments mentioned include dutasteride, RU58841, and minoxidil.
community Dermastamp vs Dermaroller vs Dermapen
Dermastamp is preferred for hair growth and skin health due to fewer scars, with recommended needle sizes of 0.5-1.5mm. Dermapen is also favored over dermarollers, which are considered dangerous.
community What are some promising/revolutionizing treatments that are in the pipeline/currently available?
The conversation discusses various hair loss treatments, including pyrilutamide, RU58841, topical dutasteride, oral minoxidil, and oral finasteride/dutasteride. It also mentions potential treatments like PP405, Verteporfin, GT20029, and AMP303.
community When is PP405 trial results medical meeting scheduled?
community It’s 2026, gentlemen. Let’s finally settle this: Does Dermarolling/Microneedling actually work…YES or NO?
Microneedling, especially when combined with minoxidil, is generally considered effective for hair regrowth, though results vary by individual. Some users report enhanced results, while others caution about potential scarring and recommend professional guidance.
community Found an interesting little article
A new painless microneedle patch shows promise in reversing hair loss. The discussion focuses on potential new treatments beyond common options like Minoxidil, finasteride, and RU58841.
community PP405 ON TEMU....seriously come on
A fake hair loss product called "PP405" is being humorously discussed, with users joking about its effectiveness and availability on resale websites. The consensus is that it's a scam, with some users sarcastically claiming miraculous results.
community Pelage will be presenting PP405 at the Masters of Aesthetics which is held from 28-30th August
The conversation expresses skepticism about the effectiveness of new hair loss treatments, comparing them to 2% minoxidil and criticizing the lack of substantial data. Users doubt the claims of a non-hormonal treatment and mention previous disappointments with products like JXL-069.
community do you HAVE to microneedle with min?
The user experienced chest pain and increased heart rate after microneedling while using topical minoxidil for hair loss. They are unsure if minoxidil is effective without microneedling.
community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.
community Feel like im not making process. Had insane shed. (Min/Fin/HRT)
The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.
community M18: I think microneedling is making my hair look thinner
The conversation is about a user experiencing hair thinning potentially due to excessive microneedling while using finasteride and minoxidil. Many suggest reducing microneedling frequency and considering alternative treatments like dutasteride or a hair transplant.
community A few days on RU58841 and JXL069, are my eyes deceiving me?
The conversation discusses a hair loss treatment regimen involving minoxidil, finasteride, RU58841, JXL069, and nizoral shampoo. The user reports seeing new black dots in areas where hair hasn't grown in years, suggesting potential regrowth.
community Kintor’s KX-826 Pyrilutamide!!
KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.
community Anyone tried winlevi for hair loss? I am curious about it as someone who doesn’t want to change my hormones systemically.
Winlevi is being considered for hair loss by someone who wants to avoid systemic hormonal changes. Minoxidil, finasteride, and RU58841 are also mentioned as treatments.
community 21F AGA - 4 month hair growth progress (Minoxidil 5%, finasteride 1mg, theradome LLLT, viviscal vitamins, PRP twice)
A 21-year-old female shared her 4-month hair growth progress using Minoxidil 5%, finasteride 1mg, Theradome LLLT, Viviscal vitamins, and PRP treatments twice. Commenters praised her progress and discussed other treatments like microneedling, but she noted her dermatologist advised against it due to potential scalp damage.
community RT1640 - Gray Hair Reversal Recipe
The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.
community Dermaroller + homemade shampoo( rosemary water+ aloe Vera+ vitamin e)
A user shared their 6-month progress using a dermaroller and a homemade shampoo made of rosemary water, aloe vera, and vitamin E for hair loss. They provided a link to photos showing their results.
community Seeking Advice on Hair Regrowth Routine: Finasteride, Minoxidil, Laser Cap?
The user is considering a hair regrowth routine using minoxidil, a laser cap, and possibly topical finasteride, while avoiding oral finasteride due to past surgery concerns. They plan to use these treatments for 6-8 months before consulting a hair transplant doctor.
community Why I still have faith in KX-826
KX-826 shows promise for hair maintenance at higher doses with minimal side effects, despite failing Phase III trials. The user believes it is more effective than Minoxidil, Finasteride, and RU58841.
community Help: Digital Perm while Thinning Hairline
A 20-year-old male experiencing hair loss is using finasteride for 8 months and is considering a digital perm but is concerned about potential hair damage, especially at the thinning hairline. Advice given includes continuing finasteride, using gentle hair products, and possibly trying topical minoxidil or CBD cream for scalp care.
community I'm already DOING EVERYTHING!!!
A 26 year old female dealing with hair loss who is considering treatments such as Spiro, minoxidil and finasteride. Other potential solutions mentioned are PRP treatment, a wig, and bio-identical estrogen combined with bica.