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      community Are these new follicle?

      in Finasteride  58 upvotes 1 year ago
      The user is questioning if black points on their scalp are new hair follicles. They are using finasteride and minoxidil for hair growth.

      community One month Umbrella Labs PP405 results.

      in Progress Pictures  56 upvotes 6 months ago
      The user tried a product labeled as PP405 from Umbrella Labs for hair loss but saw no changes, and it was revealed to be a fake or misidentified product. The user is also using finasteride, minoxidil, and other treatments but is still experiencing hairline issues.

      community 2250 graft transplant 1.5 month ago.

      in Is this regrowth?  151 upvotes 10 months ago
      A user had a 2250 graft hair transplant using both FUT and FUE methods, and is currently using finasteride, minoxidil, multivitamins, and biotin. Opinions vary on the effectiveness and appearance of the procedure, with some suggesting additional treatments or considering alternative options like shaving or using a hair system.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 3 years ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

      community SCUBE3 Biannual Injections and Microneedling

      in Technology  12 upvotes 2 years ago
      The conversation discusses biannual SCUBE3 injections and microneedling as treatments for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Why does MPB only affect the scalp

      in Research/Science  14 upvotes 1 year ago
      Male pattern baldness (MPB) may be influenced by androgen receptors in scalp hair follicles and potentially poor blood flow. Transplanted hair is not immune to DHT, and factors like inflammation and scalp tension might also contribute to hair loss.

      community Had sides on finasteride ? A word of hope.

      in Finasteride  26 upvotes 8 years ago
      A user's experience with hair loss treatments, including finasteride and other options such as RU58841, Nizoral, Pumpkin Seed, and Adenosine; the importance of being in a positive frame of mind when considering taking finasteride; and the need to address life issues before starting finasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community New study on TOPICAL pumpkin seed oil in mice

       6 upvotes 6 years ago
      The conversation discusses a new study on topical pumpkin seed oil for hair loss in mice. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Anagenic Pyrilutamid, has anyone tried this?

      in Product  2 upvotes 2 years ago
      The conversation is about personal experiences with Anagenic Pyrilutamid for hair loss and what carriers people use with it. No specific treatments or outcomes are mentioned.

      community Vertoporfin research update by Dr Bloxham

      in Research/Science  71 upvotes 2 years ago
      The conversation discusses the potential of verteporfin in treating hair loss, with some users reporting positive results and speculating that it could lead to a cure for baldness. Others are skeptical, and there's a debate on the effectiveness of verteporfin for regrowing hair and reducing transplant scars.

      community Hair transplant 8 month results

      in Progress Pictures  113 upvotes 2 years ago
      The user shared their 8-month hair transplant results from Cosmedica, involving around 3800 grafts and topical use of Minoxidil and Finasteride since the operation. They discussed the procedure details, cost, and the possibility of a second operation for crown and touch-ups.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community Finasteride and hormonal tests

      in Finasteride/Dutasteride 5 months ago
      A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.

      community 12 Month Update - Smile Hair Clinic - Dr. Erdogan

      in Transplants  1508 upvotes 1 year ago
      A user shared their positive experience with a hair transplant at Smile Hair Clinic, using treatments like oral finasteride, minoxidil, and dutasteride. They reported no side effects, significant improvement in hair density, and satisfaction with the results.

      community Estradiol mesotherapy / idea feedback

      in Female  6 upvotes 1 year ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       22 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community Ky19382 group buy results question

      in Technology  2 upvotes 4 years ago
      The conversation discusses the results of a group buy for Ky19382 related to hair loss treatments. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Injecting estrogen for hairline regrow

      in Chat  267 upvotes 1 year ago
      A user plans to undergo a temporary MtF transformation to regrow hair, using estrogen, RU58841, and Dutasteride, then revert with testosterone. Many users criticize the plan, suggesting alternatives like hair transplants, and emphasize that estrogen is not a reliable solution for hair regrowth.

      community M24 2 years difference between pics

      in Progress Pictures  109 upvotes 4 months ago
      A 24-year-old started using finasteride for hair loss after hesitating due to potential side effects, and is considering a hair transplant. Other users shared their experiences with finasteride, minoxidil, and rosemary oil, discussing effectiveness and side effects.