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      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 1 year ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community Those who have taken dutasteride what was your experience?

      in Finasteride/Dutasteride  32 upvotes 6 months ago
      Dutasteride is often preferred over finasteride for hair loss due to its stronger DHT blocking, leading to better hair regrowth for some users. However, it can cause side effects like brain fog, libido changes, and mood issues, prompting some to switch back to finasteride or adjust their dosage.

      community Any experiences with Ptd-dbm??

      in Research/Science  5 upvotes 1 month ago
      The user experienced reduced hair loss using an online serum but found it too expensive and is seeking a vendor for ptd-dbm. They are also interested in KY19382 but are unable to find it.

      community Finasteride and male phenotypes

       5 upvotes 11 years ago
      Finasteride's effectiveness and side effects may vary based on male phenotypes, with some users noting differences in response related to body and facial hair characteristics. Some users report success with lower doses, while others experience side effects, suggesting individual variability in response to the treatment.

      community Questions about DUPA and figuring out what my hairloss is (NEED INPUT BADLY)

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The conversation discusses severe hair shedding and thinning, with the original poster using finasteride, oral minoxidil, and other supplements without improvement. The discussion highlights the possibility of telogen effluvium and the importance of addressing potential underlying health issues, such as stress and gut health, rather than assuming diffuse unpatterned alopecia (DUPA).

      community Why was fluridil abandoned and never made past phase 2?

      in Chat  4 upvotes 4 years ago
      Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

      community Is oral minoxidil f***ing me up?

      in General  269 upvotes 6 months ago
      Oral minoxidil is causing significant blood pressure fluctuations and increased heart rate, leading the user to consider switching to topical minoxidil and tretinoin. The user plans to consult a cardiologist and is likely to stop using oral minoxidil.

      community Finasteride Side Effects?

      in Finasteride  4 upvotes 7 years ago
      The conversation discusses side effects of finasteride, including low libido and potential gynecomastia, with some users mocking fear-mongering while others share personal experiences. The original poster mentions using finasteride, peppermint oil, coconut oil, olive oil, and Pennzoil, and considers saw palmetto as an alternative.

      community Good hair days; finastride

      in Finasteride/Dutasteride  14 upvotes 5 years ago
      The user expresses positivity about managing hair loss and celebrates good hair days. They mention using finasteride (Propecia) as part of their treatment.

      community My 1 week experience on Pyrilutamide only

      in Treatment  14 upvotes 3 years ago
      User Arrosis shared their 1-week experience using Pyrilutamide for hair loss, noticing reduced shedding and increased libido but also experiencing headaches, dizziness, and nipple sensitivity. They plan to try a lower frequency to see if it helps with side effects.

      community 2nd day on pyrilutamide - what I noticed so far

      in Treatment  7 upvotes 3 years ago
      The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.
      Am I wrong to lose hope?

      community Am I wrong to lose hope?

      in General  98 upvotes 1 year ago
      The user is experiencing worsening hair loss despite using finasteride and oral minoxidil, and is questioning if it's a shedding phase or if the treatments are ineffective. They express regret for starting the treatments as preventative maintenance.

      community Progress (or lack there of) - Finasteride 9 months

      in Progress Pictures  11 upvotes 1 year ago
      The user has been using finasteride, minoxidil, and Nizoral for 9 months with little progress in hair regrowth and is considering switching to dutasteride. They experience daily scalp pain and anxiety, and are exploring other treatments like Head & Shoulders and consulting a dermatologist.

      community Just got my diagnosis, not allowed to have fin, not sure what to do

      in Treatment  6 upvotes 4 years ago
      A 29-year-old male diagnosed with male pattern baldness was prescribed Minoxidil with Azelaic Acid but not Finasteride due to a history of mild depression. He is considering getting Finasteride online without waiting for a 3-month evaluation and is questioning the cost of his Minoxidil prescription.

      community Guys that got their hair/hairline back are you happy?

      in Chat 3 years ago
      The effects of hair loss on mental health, treatments such as finasteride, minoxidil, RU58841 and microneedling red light therapy, and the realization that while treating hair loss can be beneficial, it does not solve all underlying insecurities.

      community Help! Gyne after 20 years of taking Dut

      in Finasteride/Dutasteride  39 upvotes 1 year ago
      A 43-year-old experienced gynecomastia after 20 years of taking dutasteride and 7.5mg oral minoxidil. Suggestions include consulting an endocrinologist, checking hormones, and considering Nolvadex or DIM supplements.

      community Tropical Dut 0.5 and Scalp Psoriasis

      in Finasteride/Dutasteride  1 upvotes 3 months ago
      The user reports that using topical Dutasteride has stopped their hair loss, and they are curious about potential side effects and regrowth. They also mention having scalp psoriasis and past SSRI use affecting libido.

      community Inflammation (and health care system) frustration

      in Female  5 upvotes 1 year ago
      A woman is frustrated with her hair loss and the slow, ineffective healthcare system in Canada. She has tried treatments like minoxidil, doxycycline, and kenalog injections, but continues to experience painful inflammation and hair loss.

      community I shaved it all off

      in Shaved/buzzed  16 upvotes 5 years ago
      The user decided to shave their head instead of pursuing a hair transplant or using drugs like minoxidil and finasteride. They are motivated to accept themselves as they are and feel more confident after taking this action.

      community Diffuse thinning is the worst. Nothing helps.

      in Update 7 months ago
      The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.