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      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  7 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Sugar and hairloss

      in Research/Science  11 upvotes 5 years ago
      Cutting sugar may not significantly impact hair loss, as DHT and androgen receptors are the main issues. Effective treatments include finasteride, dutasteride, RU58841, and minoxidil, often combined with microneedling.

      community Hairline thinning 9 after months on finasteride

      in Update  4 upvotes 8 months ago
      The user has been using topical minoxidil and finasteride for hair loss, with some regrowth at the temples but continued hairline thinning. The dermatologist suggested possible telogen effluvium due to stress and deficiencies, prescribed oral minoxidil, and may consider dutasteride if the condition doesn't improve by January 2026.

      community Are these supplements good enough or am I missing something?

      in Product 1 year ago
      The conversation discusses the effectiveness of various supplements for hair loss, with some users suggesting higher doses of Zinc and Vitamin C, while others recommend additional supplements like Saw Palmetto and Omega-3. It is concluded that multi-vitamins are often ineffective unless there is a deficiency, and excessive intake can harm hair follicles.

      community zinc + copper with finastetide/dutasteride?

      in Finasteride/Dutasteride  1 upvotes 3 years ago
      Taking zinc and copper may offset copper depletion and potentially aid hair health when used with finasteride. The user is considering whether to use these supplements alongside finasteride or wait until switching to dutasteride.

      community Any positive responses for Diffuse Thinner with Retrograde using Fin/Min/Dut

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.

      community Atherosclerosis as cause of balding and treatment

      in Treatment  61 upvotes 2 years ago
      Hair loss may be caused by calcification of capillaries in the scalp, restricting blood flow to hair follicles. A daily treatment regimen including high doses of Vitamins D and K, Magnesium, and Nattokinase could potentially decalcify these capillaries, improving blood flow and hair growth. However, some users warn against excessive Vitamin D intake and emphasize the need for medical consultation.

      community 14 months on Fin, Total T 899, serum DHT 276 — high total T may still drive scalp DHT even when blood levels look controlled

      in Finasteride/Dutasteride  3 upvotes 1 month ago
      A 23-year-old male has been using finasteride and topical minoxidil for 14 months with slight improvement, but recent shedding led him to switch to a new minoxidil formulation without success. He is considering using topical RU58841 or dutasteride to better address scalp DHT, as his bloodwork shows high total testosterone and mid-range DHT levels.

      community Blood Results before and after Topical Finasteride mix with Minoxidil

      in Finasteride  9 upvotes 6 years ago
      A user reported that after using a topical mix of finasteride and minoxidil, their DHT levels decreased, testosterone and estradiol levels lowered unexpectedly, and they are considering vitamin D3 supplements due to deficiency. They apply the mix 3-4 times a week and use minoxidil on other days. Another user commented that finasteride typically increases testosterone, not decreases it.

      community Does anyone have a list of vitamins that could help alongside dut and min?

      in Treatment  6 upvotes 4 months ago
      The conversation is about hair loss treatments, specifically using dutasteride and oral minoxidil, and exploring additional vitamins and supplements like vitamin D, zinc, biotin, and omega-3 to support hair health. Users suggest getting a blood panel to identify deficiencies and emphasize the importance of protein and overall nutrition.

      community What blood test to do before starting fin?

      in Finasteride/Dutasteride  1 upvotes 4 months ago
      A user is considering starting finasteride for hair thinning but is concerned about side effects like low libido and gynecomastia. They plan to consult a dermatologist and are advised to test DHT, testosterone, and estradiol levels.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  10 upvotes 9 months ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community Anyone here have experience with ferritin level and hair?

      in Treatment  4 upvotes 4 months ago
      Low ferritin levels can affect hair density, and increasing ferritin through iron supplements may help with regrowth. It's suggested to maintain ferritin levels between 70-100 ng/mL and check other micronutrients for optimal hair health.

      community I know why people are non responder to hair treatment

      in Minoxidil 2 years ago
      Improving diet and taking supplements like Biotin, B12, D3, iron, zinc, and protein can enhance the effectiveness of hair treatments. However, responses to treatments like Minoxidil and finasteride vary, and some users report no improvement despite a good diet.

      community 31M - major hair shedding after weight loss + stopping vitamins — help!

      in Minoxidil  4 upvotes 1 year ago
      A 31-year-old male experienced hair shedding after rapid weight loss and stopping vitamins, despite using minoxidil and other supplements. He is considering Saw Palmetto and Pumpkin Seed Oil instead of finasteride due to trying for kids, and is concerned about high ferritin and DHEAS levels.

      community Does finasteride decrease free testosterone?

      in Research/Science  186 upvotes 1 year ago
      Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

      community Yet another hrt update (4 months estradiol and spiro + > 4 years of fin and min) (you should absolutely not take estradiol and spiro if you look manly and want to continue to look manly)

      in Progress Pictures  5 upvotes 1 year ago
      The conversation discusses hair loss treatments, including finasteride, minoxidil, estradiol, and spironolactone, with a focus on their effects on hair regrowth and gender transition. The original poster shares their personal experience with these treatments, emphasizing that estradiol and spironolactone should not be used by those who want to maintain a masculine appearance.

      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  33 upvotes 3 months ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community Hormonal panel after 1 year of treatment - DHT levels doubled!!

      in Finasteride/Dutasteride  7 upvotes 2 years ago
      A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.

      community My results & the importance of nutrition on hair health and growth. (M/30, Diffuse Thinner)

       5 upvotes 6 years ago
      A 30-year-old man with diffuse hair thinning shared his hair regrowth regimen, which includes increasing Vitamin D intake, taking oral castor oil, using a dermapen, and various supplements like Glycine, K2, Vitamin E, Vitamin C, Aspirin, Sodium Bicarbonate, and a multivitamin. He also mentioned inconsistent use of Minoxidil, Peppermint Oil, Zix, and topical Castor Oil, and negative side effects from Finasteride, RU58841, and Nizoral.

      community One year 1mg fin + 2,5 mg oral min

      in Finasteride/Dutasteride  5 upvotes 5 months ago
      The user has been using finasteride 1mg and oral minoxidil 2.5mg for a year, experiencing ongoing shedding since starting minoxidil. They are considering dutasteride and seeking advice on blood work for thyroid, Vitamin D, and iron levels.

      community Blood work after one year of fin/dut

      in Finasteride/Dutasteride  9 upvotes 3 years ago
      After using finasteride and dutasteride for hair loss, a user's blood tests showed almost unchanged DHT levels and some out-of-range hormone levels. They experienced side effects when taking dutasteride daily and also take supplements that boost testosterone.