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      community 3 month of profess with fin and minoxidil

      in Progress Pictures  123 upvotes 2 years ago
      The conversation discusses a user's three-month progress using topical finasteride once a day, 6% minoxidil at night, and weekly dermastamping at 1.25mm for hair loss. Commenters note the impressive results and discuss application methods and safety precautions for family members.

      community Minoxidil on the beach cocktail recipe

      in Satire  96 upvotes 3 years ago
      A satirical discussion on using minoxidil and finasteride in unconventional ways, including mixing them into drinks and other humorous methods. The conversation also touches on the potential health risks of minoxidil.

      community Pyrilutamide for non-5AR users?

      in Treatment  10 upvotes 1 year ago
      Pyrilutamide is considered by some as an alternative for those avoiding 5AR inhibitors like finasteride and dutasteride, but opinions on its effectiveness vary. Some users report similar results with fluridil and pyrilutamide, while others find pyrilutamide less effective compared to prescription treatments.

      community Im looking for a topical to add to my current stack

      in Treatment  1 upvotes 1 year ago
      The user is considering adding a topical treatment to their current regimen of finasteride and oral minoxidil to protect their temple area, with options like piro, RU58841, or topical finasteride or dutasteride. They are advised against overcomplicating their treatment, but another user suggests a topical with 8% minoxidil/dutasteride for better results.

      community Lowering the dosage or stopping?

      in Finasteride/Dutasteride  1 upvotes 4 months ago
      The user is considering lowering the dosage of finasteride and minoxidil due to side effects like mood changes, lower libido, and brain fog, while wanting to maintain hair regrowth. A suggestion was made to try a lower dose of finasteride, such as 0.2 mg.

      community Dut 0.5 EOD/MWF vs Fin 1 ED. What should I do?

      in General  75 upvotes 11 months ago
      The user is experiencing side effects from Dutasteride 0.5 mg and is considering reducing its frequency or switching back to Finasteride, while continuing with Minoxidil 2.5 mg to preserve their hairline. They are unsure if the increased Minoxidil dose is sufficient for regrowth.

      community Pyrilutamide Phase 3 on its way

      in Treatment  128 upvotes 4 years ago
      Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       22 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community Oral minoxidil or topical with tretinoin?

      in Minoxidil  6 upvotes 1 year ago
      The conversation discusses the effectiveness of oral minoxidil versus topical minoxidil with tretinoin for hair regrowth, with some users suggesting oral minoxidil might be more effective for non-responders to topical treatments. Concerns about side effects and the role of enzymes in activating minoxidil are also mentioned.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community ED or only bad habits???) 21 M

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      A 21-year-old experienced erectile dysfunction after using finasteride and consuming multiple drugs, including MDMA, LSD, and weed. He plans to quit finasteride and weed, improve his habits, and consider alternative treatments like mesotherapy with dutasteride.

      community Will Breezula simply be an overhyped flop?

      in Treatment  16 upvotes 5 months ago
      Breezula is seen as potentially overhyped, with concerns about its cost, effectiveness, and long-term benefits compared to existing treatments like finasteride and minoxidil. Some users believe it could complement existing treatments, while others are skeptical about its impact and prefer waiting for newer options like GT20029 and PP405.

      community Estradiol mesotherapy / idea feedback

      in Female  6 upvotes 1 year ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

      community Pyrilutamide (KX-826) vs CB-03-01 which one do you think is better?

      in Product  8 upvotes 3 years ago
      The conversation is about comparing hair loss treatments Pyrilutamide (KX-826) and CB-03-01, discussing their cost, side effects, and effectiveness. The user questions whether to try CB-03-01, which is more expensive and potentially less effective, or switch to the cheaper and possibly better Pyrilutamide.

      community Where can I get this topical solution compounded?

      in Treatment  1 upvotes 3 months ago
      A user is seeking a pharmacy to compound a topical solution containing Minoxidil, Finasteride, Alfatradiol, Melatonin, Latanoprost, and either RU58841 or Pyrilutamide. They prefer a professional compounding lab over DIY methods.

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 2 years ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

      community Next best option after low dose finestride

      in Finasteride/Dutasteride  3 upvotes 1 month ago
      The user experienced hair regrowth with finasteride and minoxidil but faced libido issues, leading them to try alternatives like novamaine and a low-dose finasteride/minoxidil solution, which still caused side effects. They are considering reducing the solution's volume, stopping finasteride, or using minoxidil alone, while others suggest alternatives like dutasteride or clascoterone.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Ordered PTD-DBM from tailor made

      in Product  4 upvotes 5 years ago
      The conversation discusses hair loss treatments, including finasteride, microneedling, minoxidil, and PTD-DBM. The user has not noticed significant regrowth and is considering cost-effective options like valproic acid.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.