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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Extremish regimen - dermarolling too hard?

       4 upvotes 8 years ago
      The user is using a hair loss treatment regimen that includes RU58841, minoxidil mixed with finasteride, adenosine, dermarolling with lidocaine cream, and biotin. They are questioning if they are dermarolling too aggressively and are willing to accept baldness if no improvement is seen in 6 months.

      community My summation of PP405 - looks promising

      in Research/Science  208 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community Ordered copper peptides - how to apply?

      in Treatment  1 upvotes 1 year ago
      Gizzela is unsure about the dosage and frequency of copper peptides and asks if they can be used with Stemoxydine. They seek advice on applying these treatments together.

      community Mix Pyrilutamide powder in Minoxidil solution?

      in Minoxidil  3 upvotes 2 years ago
      Mixing Pyrilutamide powder with Minoxidil solution is being considered. The Minoxidil solution contains Minoxidil 5%, Azelaic acid 5%, ABN complex 0.8%, Retinol 0.025%, Caffeine 0.001%, and a delivery vehicle.

      community Using a 2-deoxy-d-ribose gel. My experience 2 weeks in.

      in Treatment  38 upvotes 8 months ago
      The user switched from minoxidil to a homemade 2-deoxy-d-ribose gel and noticed no hair fall after two weeks, despite stopping minoxidil. The gel includes water, 2-deoxy-d-ribose, vegetable glycerine, 2-phenoxyethanol, sodium alginate, and rosemary oil, and the user reports healthier-feeling hair.

      community Min/Fin is pure magic. Seriously. Read below

      in Treatment  9 upvotes 1 year ago
      A user reported significant hair growth improvements using 1mg finasteride and 2.5mg minoxidil daily, despite minor side effects. The doctor advised against combining multiple treatments to identify what works.

      community My Telogen Effluvium journey after a bad Keratin Treatment

      in Female  5 upvotes 2 years ago
      A user shared their experience with telogen effluvium triggered by a keratin treatment, leading to significant hair loss. They found improvement using aloe vera with rosemary, a protein and iron-rich diet, and patience.

      community Purchasing and Shipping Alpecin DMG to the United States.

      in Product  3 upvotes 6 months ago
      A user is seeking help to purchase and ship Alpecin DMG to the United States due to issues with eBay sellers. They prefer Alpecin DMG over minoxidil because of concerns about minoxidil's effects on insulin production, as they have diabetes.

      community Binding affinity of pyrilutamide!

      in Update  169 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Anyone looking at peptides for hair?

      in Treatment  10 upvotes 2 months ago
      The conversation discusses interest in peptides for hair loss, specifically mentioning ahkCU and ghkCU. A user is considering adding ghkCU to their treatment regimen.

      community Is Stemoxydine a DHT blocker.?

      in Product  2 upvotes 1 year ago
      Stemoxydine is not a DHT blocker; it works independently to stimulate hair growth. Users discussed its function and clarified it does not block DHT.

      community This shedding fase is absolutely brutal

      in Progress Pictures  183 upvotes 11 months ago
      The user is experiencing severe hair shedding despite using minoxidil, finasteride, ketoconazole shampoo, and dermarolling. They are considering changing treatments after stopping dermarolling and switching finasteride brands worsened the shedding.

      community Minoxidil absorption and washing hair

      in Microneedling  8 upvotes 3 years ago
      User asks if washing hair or using hair fibers after minoxidil dries is okay and if dry scalp means full absorption. Some doctors and sources say 50-75% absorption occurs after an hour.

      community Shoutout to Zinc pyrithione and Piroctone olamine

      in Product  3 upvotes 11 months ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  10 upvotes 7 months ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community Advice on homemade / DIY topical finasteride?

      in Treatment  9 upvotes 7 months ago
      The conversation is about making homemade topical finasteride by crushing pills and mixing them with ethanol and propylene glycol or minoxidil. Users discuss sourcing options and share experiences with DIY solutions.

      community Minoxidil: Sulfotransferase Enzyme booster AVAILABLE NOW

      in Minoxidil  7 upvotes 2 years ago
      A new product, Minoxidil booster, which enhances sulfotransferase enzyme activity in the scalp, is now available. The user has started using this product, applied before Minoxidil, to improve their hair loss treatment results.

      community Pyrilutamide isn’t failed at all.

      in Technology  11 upvotes 1 year ago
      Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.