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      community Minoxidil: How It Changes the Scalp Hormone Environment

      in Research/Science  80 upvotes 3 months ago
      Minoxidil increases blood supply to the scalp, strengthening dormant follicles and extending the growth phase, but may increase scalp activity that can be countered with DHT blockers. Women experiencing side effects from finasteride or dutasteride for hair loss might consider alternatives like estrogen, especially if on birth control.

      community Questions regarding starting Dermarolling, Rogaine foam, retinal/retinol

      in Minoxidil  3 upvotes 4 months ago
      The conversation discusses using Rogaine (minoxidil foam) for hair loss, with questions about enhancing its effectiveness with tretinoin or retinol and incorporating dermarolling. The user has been using finasteride for 7 years and is considering starting minoxidil despite concerns about shedding.

      community Thoughts about ORAL ketoconazole? (pills)

      in Ketoconazole 5 months ago
      Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

      community No progress from Feb 2025 to Jan 2026

      in Progress Pictures  15 upvotes 5 months ago
      The user has not seen significant progress in hair growth using topical minoxidil, finasteride, and biotin shampoo over a year. Suggestions include switching to dutasteride, adding microneedling, and considering other treatments like scalp massages and blood tests.

      community Treatment effectiveness for oral vs topical

      in Treatment  3 upvotes 7 months ago
      Oral treatments for hair loss, like Dutasteride and Minoxidil, may be more effective than topical ones, though topical formulations can be similarly effective except for Minoxidil. Topical treatments can be a chore to apply and are often used as supplements to oral treatments.

      community Let's talk about the use of minoxidil 15%

      in Minoxidil  5 upvotes 7 months ago
      Minoxidil 5% is no longer effective for the user, who is considering stronger minoxidil or oral options despite availability issues. Suggestions include trying minoxidil 15%, oral minoxidil, microneedling, and exploring other treatments like finasteride and dutasteride.

      community Is Retinol effective by itself?

      in Treatment  3 upvotes 10 months ago
      Retinol is not effective alone for hair loss; tretinoin is more potent and sometimes mixed with minoxidil. Retinoids do not stop hair loss, and finasteride or dutasteride is necessary for that.

      community Oral minoxidil vs Topical Minoxidil w/ Retinoic acid

      in Minoxidil  6 upvotes 10 months ago
      Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.

      community Important reminder for cat owners ⚠️

      in Minoxidil  441 upvotes 11 months ago
      Minoxidil is extremely toxic to cats, even in small amounts, and can be fatal. Switching to oral minoxidil is safer for cat owners, but precautions should still be taken to prevent exposure.

      community literally dht beef bruhhsmhmmhh😡😡😡😡😡😤

      in Finasteride/Dutasteride  128 upvotes 1 year ago
      The conversation discusses using finasteride, dutasteride, RU58841, and testosterone to combat hair loss and block DHT, with some users expressing concerns about side effects and vegan options for medication. The discussion also touches on personal experiences with hormone treatments and the desire to maintain a youthful appearance.

      community Is this Better Than Topical Minoxidil? Topical Diazoxide

      in Research/Science  6 upvotes 1 year ago
      Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

      community Minoxidil+ Spray by keep does it contain propylene glycol?

      in Minoxidil  1 upvotes 1 year ago
      The user is using Dutasteride and oral Minoxidil for hair regrowth and is considering adding topical Minoxidil but is allergic to propylene glycol, which is present in the product they found. They need a solution with tretinoin that does not contain propylene glycol.

      community Any experiences with/thoughts on Zeuss sublinguals?

      in Product  5 upvotes 1 year ago
      Zeuss sublingual products for hair loss, including finasteride and a finasteride-free option, are discussed for their potential to reduce side effects through sublingual delivery. The inclusion of copper peptides is noted, but the high price is a concern without more user feedback.

      community Why microneedling can ruin a hair transplant

      in Microneedling  14 upvotes 1 year ago
      Microneedling's effectiveness for hair growth is debated, with some suggesting it enhances minoxidil absorption, but evidence is inconclusive. Concerns exist about its impact on hair transplants, and opinions vary on its use with other treatments like RU58841 and stemoxydine.

      community Is there any hope for my hairline?

      in Treatment  10 upvotes 1 year ago
      The user experienced reduced hair fall with topical minoxidil and finasteride but no regrowth, and faced hormonal issues with oral finasteride. They are considering a hair transplant and exploring treatments like topical dutasteride, oral minoxidil, microneedling, and hair supplements.

      community Tretinoin and minoxidil. How do you guys use this combo

      in Minoxidil  16 upvotes 1 year ago
      Tretinoin is used with minoxidil to enhance hair growth, with some users applying tretinoin before minoxidil to improve results. Some users report success with this combination, while others experience irritation or dryness.

      community Ultimate Stack without nuking your gender (you'll go broke)

      in Treatment  86 upvotes 1 year ago
      A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

      community He used Dutasteride for 20 years. Interview

      in Treatment  114 upvotes 1 year ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 1 year ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

      community Help! Minoxidil or Duta to avoid Shed of long hair.

      in Female  8 upvotes 1 year ago
      The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

      community How to Keep Your Hair on Steroids

      in Treatment  26 upvotes 1 year ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

      community Topical minoxidil and salicylic acid

      in Minoxidil  6 upvotes 1 year ago
      The user has been using finasteride for 6 months with decent results and recently added topical minoxidil. They are concerned that salicylic acid in their skincare products might reduce minoxidil's effectiveness.

      community What’s the highest minox % you home brewed ?

      in Minoxidil  2 upvotes 1 year ago
      A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

      community What treatment helped you with oily scalp/hair loss?

      in Chat  8 upvotes 2 years ago
      The user has been dealing with an oily scalp, seborrheic dermatitis, and hair loss for 18 months, using finasteride without improvement. Another user suggested dutasteride for reducing scalp oiliness.

      community Does anyone take oral Dut & Topical Min?

      in Minoxidil  7 upvotes 2 years ago
      The conversation is about the use of oral Dutasteride and topical Minoxidil for hair loss. There is little discussion found on this specific combination of treatments.