The user is seeking an alternative solvent for pyrilutamide due to skin irritation from ethanol and propylene glycol. They experienced similar issues with topical minoxidil.
After 4 months of using topical finasteride and minoxidil, blood tests showed increased E2, Test, and Prolactine levels. The user is concerned about potential side effects like gyno and is seeking advice on managing these values.
A 19-year-old is experiencing hair thinning and recession above the temples, causing stress and consideration of starting finasteride despite financial constraints. They are unsure whether to begin treatment immediately or wait to assess the situation further.
The user experienced hair loss since 2021, tried various treatments, and is currently using oral minoxidil and finasteride since December 2024. They are experiencing shedding, which is common when starting or stopping treatments, and are advised to continue the current regimen as it may stabilize over time.
Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.
RU58841 is not FDA approved, and users are discussing its availability and legitimacy in India, with some mentioning brands like Vantanex and Capomil. One user warns about the risk of gyno from RU58841, advising to stop use at the first sign of sensitivity.
The user experienced hair loss after Covid and started using topical minoxidil, then switched to oral minoxidil, along with Nizoral shampoo, ketoconazole shampoo, clobetasol propionate, and clindamycin ointment, which significantly reduced hair loss and scalp issues. Other users suggested trying finasteride for better results.
Peptides like GHK-Cu, BPC-157, and TB-500 have significantly reduced hair loss, with GHK-Cu being particularly effective. The discussion also covers the high cost of these peptides and explores more affordable purchasing options.
A user experiencing diffuse thinning since age 18 describes their hair as unhealthy, dry, thin, and hard, with texture changes cycling between good and bad every few weeks. They are not on any medication, only taking vitamins and supplements.
User experienced hair density decrease after 1 year of finasteride. Others shared similar experiences, suggesting it could be a temporary shed and discussed various treatments like dutasteride, minoxidil, dermaroller, and ketoconazole.
Hair loss discussion focuses on adding an anti-androgen to stack with topical finasteride. Eucapil (fluridil) is suggested for its safety and minimal side effects.
A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.
Pelage Pharmaceuticals' PP405 aims to treat hair loss by reactivating dormant hair follicle stem cells, showing promising results in early trials. The company plans to present their findings at the American Academy of Dermatology Annual Meeting in 2026.
The user has been using oral finasteride for 15 months and oral minoxidil for 6 months, and developed alopecia areata, for which a dermatologist prescribed calcipotriol/betamethasone. The treatment is helping, but the user is experiencing another shedding phase and is concerned about the effects of the steroid cream and the cause of hair loss.
Finasteride users report reduced libido and increased hair shedding initially, but some see these as temporary or manageable side effects. Vitamin E and D-3 supplements are discussed as potential aids for libido and mood.
Low Dose Naltrexone (LDN) may reduce inflammation in alopecia conditions. It is discussed as a potential adjunct treatment with finasteride or dutasteride for androgenic alopecia.
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
A user recovered from severe Telogen Effluvium using 1mg finasteride and 2.5mg oral minoxidil within four months. Another user regained 80% hair density with finasteride and minoxidil over two years, and is now trying dutasteride.
A 25-year-old experienced worsening hair loss and side effects like low libido and watery semen after using minoxidil, finasteride, and later switching to dutasteride. Despite trying various treatments, including topical solutions and micro-needling, they saw no improvement and are now seeking advice.
User experienced side effects from topical finasteride, including penile pain and reduced sexual satisfaction, and is unsure whether to resume or avoid the treatment. They are seeking advice on whether tapering off the drug might help.
The user experienced severe side effects from oral finasteride, including sexual dysfunction and mental health issues, and switched to topical finasteride, which led to significant hair shedding. They are considering other treatments like RU58841 or topical dutasteride and are advised to check testosterone levels and address potential underlying health issues.
A 28-year-old male is experiencing hair loss, itching, soreness, and numbness on the scalp, with symptoms including dry, brittle hair and scalp irritation. Treatments tried include Nizoral, salt water, various oils, and antihistamines, with limited success; a chemist suggested a possible fungal infection, while a doctor suspected male pattern baldness.
A 27-year-old Asian male is treating hair loss with 1mg oral finasteride, topical minoxidil twice daily, and 1.5mm microneedling weekly. The discussion is about his progress with these treatments.
Hair loss from seborrheic dermatitis can be temporary. Treatments discussed include Minoxidil, finasteride, and RU58841, along with collagen and biotin supplements.
The user "OP" shared their hair loss journey, detailing their treatment regimen, which includes topical minoxidil, dutasteride, various vitamins, keto shampoo, derma rolling, and oils. They experienced significant shedding around month 6 but believe it has stopped, with hair regrowth resuming.
The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.
The user is experiencing white flakes and a greasy look from using a topical solution containing 0.025% finasteride, 8% minoxidil, 0.01% retinoic acid, and 1% hydrocortisone. Suggestions include reducing application frequency, using a brush to clean the scalp, and considering alcohol-free alternatives.
A user experienced increased estradiol, nipple tenderness, and ED after taking finasteride. They are considering dose reduction to mitigate these effects.
Gym and creatine can cause hair loss by increasing testosterone and androgenic activity. DHT blockers may help some, while others need androgen suppression with topical AA like RU or Pyri.