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PP405 is a promising new treatment for hair loss. It performs three actions in one, potentially offering a cure.

The conversation discusses various hair loss treatments, including minoxidil, finasteride, dutasteride, RU58841, microneedling, ketoconazole shampoo, and laser therapy. Users emphasize the importance of consistency, patience, and individual response to treatments.

The conversation discusses experiences with topical dutasteride for hair loss, comparing formulations from FUEClinic, MinoxidilMax, and Strut. Users share their results and side effects, with some preferring topical over oral treatments to minimize systemic absorption.

A user shared their 3-month hair growth progress using 1mg oral finasteride, 5% topical minoxidil, and microneedling with a 1.5 mm dermaroller twice weekly. The user received positive feedback and expressed a desire for thicker hair in the future.

The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

A 19-year-old diagnosed with AGA was refused finasteride by a dermatologist who cited fertility concerns and prescribed minoxidil, vitamins, and shampoos instead. The user is unsure about using minoxidil and considers finding another dermatologist.

A user shared their 2-month progress on finasteride 1mg daily and weekly derma rolling, showing noticeable hair regrowth. Replies confirm visible improvement, though some attribute it partially to lighting.

People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.

The user, who experienced hair loss at the temples due to psoriasis at 17, is now 21 and considering treatment options. They are inquiring about using minoxidil once a day, whether non-AGA hair loss will persist after stopping minoxidil, and if alternative remedies like Detumescence therapy, rosemary and peppermint oils, and microneedling could be sufficient.

Tretinoin's effectiveness for hair regrowth alone is questioned, with interest in its use with oral minoxidil. The discussion also considers whether finasteride or dutasteride is the better DHT blocker and if switching to dutasteride is advisable for those without side effects from finasteride.

The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.

User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.

With a head full of hair, like a phoenix! This user has experienced positive results from using topical minoxidil and oral finasteride for 12 months, followed by 5 months of only topical use, as well as microneedling before application for 4 months. They are now considering a hair transplant in order to further enhance their results.

A user is seeking recommendations for purchasing 1mm to 1.5mm derma rollers in the U.S. for better hair growth results, as they are currently using a 0.25mm roller.

Kintor Pharma successfully dosed the first patient in a Phase II trial for KX-826 for acne vulgaris. Users are more interested in results for male pattern baldness (MPB).

The user underwent a hair transplant in Turkey and has been using a topical solution with 5% minoxidil and 0.0025% finasteride, along with Ket 2% shampoo and derma rolling, to maintain hair status. They are uncertain about improvements, noting thicker non-transplanted hair, and are considering increasing medication frequency to enhance results.

A 36-year-old started using finasteride (0.3-0.5mg daily), 5% minoxidil foam, and weekly dermarolling/dermapen treatments to address hair loss. They also began taking supplements for low ferritin and vitamin D, hoping to improve hair thickness and cover a bald spot.

The conversation discusses switching from a dermaroller to a dermastamp for microneedling, with recommendations on technique and frequency to avoid bleeding. The user also uses minoxidil and dutasteride for hair loss treatment.

Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

The Ordinary multipeptide hair serum is used alongside treatments like minoxidil, topical finasteride, and derma rolling, with some users reporting hair thickening and vellus hair regrowth. However, experiences vary, and some users are skeptical due to the lack of solid evidence and mixed efficacy reports.

Pelage executives' hairlines were discussed, with speculation about them using PP405 for hair regrowth. Concerns were raised about using untested drugs, with some suggesting executives might not risk using them without safety data.

A non-binary transfeminine person experienced significant hair regrowth after starting finasteride, minoxidil, microneedling, and hormone replacement therapy with estradiol. They encourage trans individuals concerned about hair loss to consider estrogen as it has greatly improved their hair condition.

OP asked if Alfatradiol 0.1% can maintain hair after a transplant. Responses suggest using stronger treatments like finasteride or micro-dosing oral finasteride instead.

User shared 6-month progress using topical finasteride, biotin, and occasional dermarolling, reporting no side effects except possible depression. Replies praised the results and shared personal experiences with finasteride.

The user reports using 2.5 mg oral minoxidil, 1mg finasteride, ketoconazole, and monthly dermarolling for hair loss over six months, and is asking if there's hair regrowth or stabilization. Another person suggests increasing dermarolling frequency, possibly using more dutasteride, topical minoxidil, or a retinoid cream to improve minoxidil absorption.

Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

A 33-year-old attempted hair regrowth after 10 years of baldness using topical finasteride, minoxidil, micro-needling, a laser cap, and later oral dutasteride. They noticed some regrowth, especially vellus hairs, and are considering a hair transplant or other treatments despite side effects.

The user is seeing positive results in hair growth using a combination of topical minoxidil, finasteride, microneedling, and keto shampoo. They also use a red light panel for collagen rebuilding and are happy with the progress.

Female, 28, losing hair since 17, using 200mg Spiro. Tried Minoxidil and ketoconazole with limited success, considering oral minox and seeking alternative treatments from cosmetic dermatologist.

User reports 2 months progress using daily oral fin 1mg, twice daily topical min 5%, and intermittent dermapen. Others share their experiences, suggesting patience and additional treatments like alternating shampoos, using conditioner, tretinoin, and vitamins.