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      community Tressless When They See Verteporfin Results

      in Transplants  181 upvotes 2 years ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.
      Three weeks in and temples are responding

      community Three weeks in and temples are responding

      in Journals / Progress Pictures  35 upvotes 2 months ago
      The user reports improvement in temple hair after three weeks of using finasteride, minoxidil, ketoconazole, microneedling, stemoxydine, and follicopeptide. They note visible progress by maintaining the same hair length for comparison.

      community Is the clinic diagnosis legit to you ?

      in Transplants  1 upvotes 1 year ago
      The clinic diagnosed the user with NW3 and AGA, noting thinning hair despite using finasteride for 3 years, and suggested PRP and Mesotherapy before considering a transplant. The user questions the necessity of these treatments without confirming retrograde alopecia and its treatability.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 6 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community PP405 - A True Breakthrough or Another Disappointment?

      in Research/Science  32 upvotes 1 year ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community Likelihood of a new treatment?

      in Chat  6 upvotes 1 year ago
      New hair loss treatments like stem cells, hair cloning, and gt20029 are unlikely to be available in the next 5-10 years, with some trials possibly starting by 2026. Current treatments like Minoxidil and Finasteride have been used for decades, and new developments depend on funding and successful trials.

      community 6.5 Month Progression 33/Female

      in Female  46 upvotes 3 years ago
      Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

      community Procyanidin B2 Supplement

      in Research/Science  13 upvotes 5 years ago
      User seeks Procyanidin B2 supplement source and asks for dosage comparison. Another user requests study details and apple type importance.

      community Estimate of GT20029 on the grey market?

      in Technology  9 upvotes 2 years ago
      The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

      community Is this regrowth * finasteride only *

      in Is this regrowth?  118 upvotes 8 months ago
      The user is using finasteride 1.25mg three times a week for hair regrowth and reports no significant side effects except watery semen initially. They also use a local caffeine shampoo and are considering haircuts to improve appearance.

      community Are These Long vellus Hair an Indikator for regrowth?

      in Is this regrowth?  1 upvotes 2 years ago
      A user, 35M, has been using oral finasteride for 5 years and 5% minoxidil for 3 years, which stopped hair loss but didn't promote regrowth. After starting RU58841 5 months ago, they noticed long, translucent hairs and are asking if these hairs will darken and how to encourage this.

      community Im shedding more short hairs??

      in Is this regrowth?  1 upvotes 1 year ago
      A 16-year-old experiencing hair thinning noticed a shift from shedding long hairs to shorter hairs, while using Vitamin D, biotin supplements, ketoconazole shampoo, and improving diet. They are questioning if the short hairs indicate regrowth or androgenetic alopecia (AGA).

      community Is this an improvement? July 2024 vs. Now

      in Is this regrowth?  11 upvotes 1 year ago
      The user has been using Finasteride 1mg daily since July 2024 and Estradiol since December 2024, noticing thicker and less oily hair with regrowth at the temples. Other users agree that the hair has improved significantly.

      community The Big Fat Layer II

      in Research/Science  26 upvotes 5 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

      community My Theory Of Androgenic Alopecia

      in Research/Science  20 upvotes 7 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 3 months ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community My 3200 grafts hair transplant surgery update

      in Progress Pictures  343 upvotes 10 months ago
      A user shared their positive experience with a 3200 graft hair transplant surgery, costing 1.20 lakh INR, performed by a doctor with a background at Eugenix. Post-surgery, they were instructed to use minoxidil 5% topically, take finasteride tablets, and undergo PRP treatments.

      community Regrowth on 6 months Dutasteride + Update

      in Is this regrowth?  2 upvotes 1 year ago
      User reports regrowth at temples and improved hairline density after 6 months of using 0.5 mg Dutasteride daily, topical minoxidil twice daily, and vitamins. Considering adding copper peptide but concerned about overdoing it; experiencing increased shedding on the crown.