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      community KX-826 Phase 3 Results Are Out

      in Research/Science  107 upvotes 3 weeks ago
      KX-826 shows promising results for hair growth with fewer side effects, offering an alternative to finasteride and minoxidil. Users discuss combining it with minoxidil, dermarolling, and Nizoral for improved results.

      community Any experiences with/thoughts on Zeuss sublinguals?

      in Product  7 upvotes 1 year ago
      Zeuss sublingual products for hair loss, including finasteride and a finasteride-free option, are discussed for their potential to reduce side effects through sublingual delivery. The inclusion of copper peptides is noted, but the high price is a concern without more user feedback.

      community Hairloss Stack. Focused on density and Hairline

      in Progress Pictures  10 upvotes 1 year ago
      The user is using a combination of RU58841, Stemoxydine, RevivHair Serum, hair growth oil, topical Minoxidil, Alfatradiol, oral Minoxidil, and Finasteride to treat hair loss. They report no side effects from oral Minoxidil and Finasteride after 7 months of use.

      community Thinking about signing up for the setipiprant clinical trials

       4 upvotes 8 years ago
      The conversation discusses hair loss treatments, with the original poster considering joining a clinical trial for setipiprant after experiencing side effects from finasteride and disinterest in minoxidil. Some users express skepticism about setipiprant's effectiveness, while others encourage participation in the trial for potential benefits.

      community Finasteride gives me seb derm. Thoughts on zinc or other options?

      in Chat  14 upvotes 3 years ago
      A user with diffuse hair loss after taking accutane, which might have triggered genetic predisposition to AGA; their experience taking finasteride and experiencing side effects of increased oil production, increased sex drive, worsening hair texture; they are considering zinc supplementation with finasteride or other treatments such as alfatradiol or spironolactone.

      community Lysine IS helping

      in Update  5 upvotes 4 years ago
      Lysine supplementation at 2 grams daily reduced hair shedding by 25% and made hair strands thicker. The user highly recommends lysine for hair health.

      community Can anyone else relate? M23. Pictures taken on the same day.

      in Styling  413 upvotes 1 year ago
      Hair looks thinner in sunlight, and users discuss using hair fibers, minoxidil, finasteride, and considering dutasteride for hair loss. Hair fibers like Toppik help conceal thinning, and some users suggest additional treatments like derma stamping and micro-needling.

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 2 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 1 year ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community Anyone having success with breezula

       9 upvotes 6 years ago
      People are discussing the effectiveness of Breezula for hair loss maintenance. Some individuals are using Breezula alone, avoiding finasteride, and one plans to use Breezula after a hair transplant.

      community Tropical growth stimulants other than minoxidil

      in Treatment  10 upvotes 1 year ago
      The conversation discusses alternative hair growth treatments to minoxidil, including Stemoxydine, Tretinoin, adenosine, Baicalin, castor oil, Latanoprost/bimatoprost, and Redensyl. Users share their experiences and opinions on the efficacy of these treatments.

      community Odd Hair Growth (Possibly More Than Genetics?)

      in Is this regrowth?  2 upvotes 1 year ago
      A 23-year-old user shares their hair regrowth journey, questioning if genetics or other factors are at play. They use Rogaine, finasteride, vitamin B12, biotin, Thera M Plus, and derma stamping, and seek advice on their regimen and hair growth patterns.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2448 upvotes 4 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  51 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Terminal hairs growing in, but derm still says I’m going to go bald in the years to come??

      in Chat  6 upvotes 10 months ago
      A 30-year-old woman with a history of anemia and low vitamin D experienced hair shedding, which improved after addressing nutrient deficiencies. Despite regrowth of terminal hairs, her dermatologist recommended treatments like minoxidil and spironolactone to prevent future bald spots, but she is cautious due to family history of hormone-related cancers.

      community Clascoterone/ Breezula will it work

      in Research/Science 2 days ago
      Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.