community This sub trying to get its hands on Pyrilutamide in light of the recent results
Hair loss treatments including Minoxidil, Finasteride and RU58841; with a focus on Pyrilutamide could potentially be used as an effective treatment.
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720-750 / 1000+ resultscommunity due to medication, age, over use of color and heat, my hair began to fall out and break. I shaved my head (35F) and I’m horrified at myself now
A woman experienced significant hair loss due to medication, hair coloring, and heat damage, leading her to shave her head and feel distressed. She is considering using wigs and possibly oral minoxidil to manage the situation while her hair regrows.
community Doing sulforaphane since 2 weeks got new babyhairs
The user noticed new baby hairs after using sulforaphane but is still experiencing shedding. They are seeking a supplement to stop shedding, possibly grape seed extract.
community Latanoprost from the gray market?
The conversation discusses sourcing pure latanoprost from the gray market for research and making a homemade solution. Concerns about potential dangers and experiences with this method are raised.
community Opinions on LLLT? Is it useless after stopping it?
Low-Level Laser Therapy (LLLT) is considered expensive and may not provide significant benefits, with some users suggesting alternatives like finasteride, minoxidil, and microneedling. Many users report limited success with LLLT and similar treatments, recommending more proven options instead.
community HMI 115 hasn't done phase one yet for AGA?
User asks if HMI 115 hasn't done phase 1 for AGA in humans. Conversation includes treatments Min, Fin, and RU.
community Patent for topical resveratrol and melatonin for AGA
The conversation discusses a patent for using topical resveratrol and melatonin to treat androgenetic alopecia (AGA) and also mentions interest in topical sulforaphane as a treatment.
community The other day I had a random discussion about not eating the livers of predators like polar bears because you can get vitamin A poisoning, my nurse roommate looked up symptoms and found telogen effluvium was one of them...
A user experienced hair thinning possibly due to excess vitamin A from taking extra gummy vitamins. They stopped taking the vitamins and are seeking advice on hair regrowth and managing vitamin A levels.
community First patient dosed with Pyrilutamide (Kintor) Phase III
First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.
community 14 year old struggling with hair loss
A 14-year-old is experiencing significant hair loss and was prescribed Aminexil by a dermatologist. They are concerned about potential side effects.
community Huge Group Buy is Now Live with New and Existing Treatments
A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.
community I thought red light was a scam this entire time. Anyone know where I can buy a decent red light cap that isn’t some aliexpress junk that doesn’t deliver enough irradiance?
The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. The user is also interested in purchasing a high-quality red light cap for hair growth.
community The cure we've been ignoring: Anal Dutasteride
The conversation humorously discusses using anal administration of Dutasteride as a novel method for treating hair loss, suggesting it could target DHT production more effectively. It includes satirical comments about the method's potential effects and absurd outcomes.
community Tressless: The Sub Where people fear monger about Finasteride, but advocate for Oral Minoxidil.
Oral minoxidil is considered unsafe due to severe side effects and requires close medical supervision, while oral finasteride is viewed as safe and effective. There is debate over the fear-mongering around finasteride and the downplaying of minoxidil's risks, with some users advocating for proper health screenings before use.
community Full Album of My Results - Dermaroller/pen + minox
User 74775446 shares successful hair regrowth results using dermaroller/pen and minoxidil. Others discuss their experiences and concerns about finasteride side effects.
community Shedding tremendously on RU5841
The user is experiencing significant hair shedding after starting RU58841, despite using dutasteride and oral minoxidil for over a year without stabilization. Others suggest continuing the treatment as shedding can be a normal phase, but caution that RU58841 is unpredictable.
community 2.5 years on fin + min – regrowth, shedding phases, LLLT stabilized
The user experienced regrowth and stabilization in hair density using finasteride, minoxidil, a derma roller, and an LLLT helmet, but noticed a recent decline in hair quality. They only take finasteride orally and are unsure about the effectiveness of the LLLT device.
community This is what finally helped me!
A 33-year-old woman experienced significant hair loss and found relief using Mary Ruth’s liquid morning multivitamin + hair growth and Nioxin shampoo and conditioner. She noticed reduced shedding and longer hair growth after three months of use.
community What are the alternatives to spironolactone for AGA?
The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.
community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?
A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.
community does redensyl allow you to maintain your hair after stopping it contrary to what happens when stopping minoxidil ?
The conversation is about whether stopping Redensyl, unlike Minoxidil, allows you to maintain hair growth benefits. The user is considering Redensyl as an alternative to Minoxidil due to concerns about hair loss upon cessation of Minoxidil.
community October 2025 $120M funding round for PP405 — hype justified or too early to celebrate?
Pelage secured $120 million for PP405, a non-hormonal topical hair loss treatment, sparking debate on its potential as a breakthrough. Concerns about finasteride's side effects persist, with some suggesting alternatives like topical finasteride or dutasteride.
community How can ru-58841 be effective if pyrilutamide failed phase 3 clinical trials?
The conversation discusses the effectiveness of RU58841 for hair loss compared to pyrilutamide, which failed to show significant hair regrowth in trials. Some users report personal side effects with RU58841 and question the criteria for success in hair loss treatments.
community [Research] RU-58841/Pyrilutamide and impacts on male fertility
The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.
community Update: .5mg Dut, Min 5% foam, Olly hair gummies- all daily
The user reports progress in hair regrowth using a daily routine of 0.5mg Dutasteride, 5% Minoxidil foam, and Olly hair gummies, while discontinuing rosemary water. They are hopeful for continued improvement and have received positive feedback on their progress.
community Quitting Alfatradiol after 4 months
The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.
community Advice on Eucapil (fluridil) after minoxidil foam
User asks if applying Eucapil (fluridil) after minoxidil foam is possible. Seeks advice from others with experience.
community Just copped a 2.5 mg Dutasteride Rx. We out here.
The post and conversation are about a user named "Road2Recovery2023" who just got a prescription for 2.5 mg Dutasteride, a treatment for hair loss.
community Pp405 full presentation on new topical
A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.
community Clascoterone ph3 results ready
Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.