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      community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.

      in Chat  12 upvotes 2 years ago
      The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 7 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community LPT: Sebhorric Detmatitis Treatment

      in Treatment  7 upvotes 8 years ago
      Mixing Nizoral and T-Gel in a 1:1 ratio and using it three times a week provided relief from persistent seborrheic dermatitis. This treatment is recommended for those with stubborn SD.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 2 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.

      community Shoutout to Zinc pyrithione and Piroctone olamine

      in Product  3 upvotes 1 year ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

      community Depressed that DUPA rules me out of a transplant

      in Chat  9 upvotes 2 years ago
      A user is upset about hair loss due to seborrheic dermatitis and DUPA, which prevents a hair transplant. They mention using jojoba oil and discuss treatments like Minoxidil, finasteride, and RU58841.

      community Ru58841 completely got rid of my seb derm

      in Chat  6 upvotes 2 years ago
      RU58841 cured seborrheic dermatitis, oily scalp, dandruff, and scalp pain, improving hair health when combined with Minoxidil. Another user noted diet impacts their seborrheic dermatitis and that finasteride hasn't changed their condition.

      community Pyrilutamide 5 months results (before, after pics)

      in Progress Pictures  190 upvotes 3 years ago
      Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

      community I think Ru58841 stopped my itching.

      in Chat  4 upvotes 1 year ago
      RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 7 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Does Pyrilutamide lowers sebum production?

      in Treatment  2 upvotes 5 months ago
      Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 6 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community What is this pigmentation around my follicles?

      in Chat  29 upvotes 1 year ago
      The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

      community Pili migrans? Lichen something? Seb derm?

      in Female  19 upvotes 1 year ago
      The conversation is about a female experiencing hair loss and seeking advice on why it's difficult to regrow hair. Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned.

      community RU and cetosomal minoxidil topical

      in Minoxidil  1 upvotes 3 months ago
      Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 10 months ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community Just an encouraging post for atypical alopecia sufferers

      in Treatment  4 upvotes 4 years ago
      The user experienced eyebrow hair loss and tried various treatments, including Minoxidil, a Capsaicin-based product, Latanoprost, Bimatoprost, Castor Oil, and Travoprost. Despite initial setbacks and a brutal shedding phase, they eventually saw positive results with Travoprost, encouraging others not to give up on treatments.

      community Latanoprost shed - anyone have experience?

      in Treatment  4 upvotes 4 years ago
      The user started using topical latanoprost and dutasteride, experiencing significant hair shedding and scalp itchiness, possibly due to an allergic reaction. They are considering stopping the treatment if the shedding is linked to an allergy.

      community The best vehicle/carrier for RU58841

      in Treatment  2 upvotes 2 years ago
      The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propylene glycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.

      community Effects of 2% vs 5% min for sebderm

      in Minoxidil  1 upvotes 2 years ago
      Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

      community Ru with gloves because of Systemic absorption?

      in Research/Science  10 upvotes 2 years ago
      The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.