community 1 month of finasteride sky high estradiol
The user reported high estradiol levels after one month of using finasteride for hair loss. They discussed potential side effects and adjustments to their treatment plan.
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30-60 / 1000+ resultscommunity Finasteride increase in Estradiol?
A user experienced increased estradiol, nipple tenderness, and ED after taking finasteride. They are considering dose reduction to mitigate these effects.
community Finasteride with high estradiol levels
A 22-year-old with high estradiol levels is considering starting finasteride for hair loss. They have an upcoming endocrinologist appointment to discuss whether they should proceed with the treatment.
community 1 Year Estradiol HRT, Oral Finasteride, Bicalutamide, Cyproterone. (20MTF)
The conversation discusses a 20-year-old transgender female's one-year experience with hair loss treatments, including Estradiol HRT, oral Finasteride, Bicalutamide, and Cyproterone. Specific treatments used for hair loss are oral Finasteride and potentially Estradiol as part of hormone replacement therapy.
community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?
User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.
community After about 3 months of 2mg Estradiol (Sublingual) and 2.5mg Minox (Oral) daily
A person transitioning is using 2mg sublingual estradiol and 2.5mg oral minoxidil daily for hair regrowth, noting significant progress in three months. They plan to increase estrogen dosage and consider adding dutasteride, discussing the effects and challenges of transitioning.
community Yet another hrt update (4 months estradiol and spiro + > 4 years of fin and min) (you should absolutely not take estradiol and spiro if you look manly and want to continue to look manly)
The conversation discusses hair loss treatments, including finasteride, minoxidil, estradiol, and spironolactone, with a focus on their effects on hair regrowth and gender transition. The original poster shares their personal experience with these treatments, emphasizing that estradiol and spironolactone should not be used by those who want to maintain a masculine appearance.
community Gained weight on fin but Estradiol is in normal range?
A user gained 10-12 kg after starting finasteride but found their estrogen levels to be within the normal range. They are concerned about potential gynecomastia but are reassured by their lab results.
community Anyone who used topical bicalutamide/estradiol/cyproterone acetate /spironolacton? (Need advice)
A user is seeking advice on the efficacy and side effects of homemade topical solutions for hair loss, specifically bicalutamide, estradiol, cyproterone acetate, and spironolactone, as they cannot access RU58841 or pyrilutamide.
community for those who had high levels of testo and estradiol after start fin/dut: did it comeback to baseline or normal levels?
A user experienced increased testosterone and estradiol levels after starting finasteride/dutasteride and is asking if these levels will return to normal over time. The conversation focuses on whether these changes are temporary.
community Mechanism of action of alfatradiol (17 alpha estradiol)
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
community Does anyone have any experience with Estradiol, Cyproterone Acetate, Spironolactone, Bicalutamide ?
Some users have experienced good hair regrowth with estradiol, cyproterone acetate, spironolactone, and bicalutamide, but these treatments may cause feminization and other side effects. It's advised to consult a doctor before using these treatments, as they can lower testosterone and have significant risks.
community Can anyone share their experience of using alfatradiol (17α-estradiol; Pantostin/Ell-Cranell etc)?
The conversation is about using alfatradiol (17α-estradiol) as a hair loss treatment. The user is considering adding it to their regimen due to its safety and availability.
community Someone told me it is the increase in estradiol and estrogen from more free t that makes dht blockers work?
Finasteride and its effects on hair loss, with discussions on the role of estradiol and estrogen. Users debate whether increased estrogen from DHT blockers contributes to hair regrowth, with concerns about potential side effects like chemical castration.
community Anyone knows a legitimate online source/distributer of 17α-estradiol (Alfatradiol) powder?
The conversation is about finding a legitimate online source for 17α-estradiol (Alfatradiol) powder to make a 0.1% solution for hair loss treatment. A user suggests Anagenica as a source.
community Are there any men here who have taken bicalutamide without estradiol?
Men discussing hair loss treatments, including bicalutamide, cyproterone acetate, dutasteride, minoxidil, and RU58841. They share experiences and concerns about side effects like infertility, liver health, and feminization.
community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)
User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.
community How to choose between topical antiandrogen (Pyrilutamide) vs topical Alfatradiol (17α-estradiol) as an add-on treatment?
The user is considering adding Pyrilutamide or Alfatradiol as a topical treatment for hair loss after oral Finasteride and Dutasteride became less effective. Other users suggest Pyrilutamide for its safety profile, while one user shares positive experiences with RU58841 for reducing scalp itch and improving hairline.
community Pre-Fin Blood Test, Are my Estradiol Levels Too High For Finasteride?
The user is considering starting finasteride for hair loss but is concerned about potential side effects due to their estradiol levels being near the upper limit. They have consulted a doctor who confirmed their levels are okay to start the treatment.
community 10 Months of Nuclear Stack [Dut, Min, Keto + Estradiol & Spironolactone (MtF HRT)] -- Does it need more time or does it need a transplant?
The post discusses using a combination of Dutasteride, Minoxidil, Ketoconazole, Estradiol, and Spironolactone for hair regrowth. Users suggest it needs more time and possibly a transplant, with some sharing personal experiences and side effects of similar treatments.
community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)
The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.
community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)
User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.
community 4 years; fin 1mg/day @ 4 years; minox twice daily @ 3 years; estradiol 5mg/day @ 3 months; spiro 100 mg /day @ 3 months (Wet hair because it's easy to hide issues with dry hair)
The user shared their 4-year hair regrowth progress using finasteride, minoxidil, estradiol, and spironolactone. They noted significant regrowth by the second year and additional benefits from estradiol and spironolactone.
community 9 months of minoxidil , finasteride, spironolactone, estradiol
User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.
community How well can HRT reduce scalp tension?
A trans woman is curious about the impact of HRT on hair regrowth and scalp tension. Her current regimen includes finasteride, spironolactone, estradiol, ketoconazole, vitamin D, iron, and plans to add oral minoxidil and restart derma rolling.
community My blood work as a person with Ed suffer
High estradiol levels may contribute to erectile dysfunction (ED) and can be addressed with lifestyle changes or medication. It's important to consult a medical professional for treatment options.
community A rare case? Or a blind spot? Hair loss caused by low T + e2
Low testosterone and estradiol may contribute to hair loss, and blocking DHT without sufficient hormone levels might hinder regrowth. The discussion highlights the importance of hormone balance, with some considering supplements and lifestyle changes to support hair health.
community Feel like im not making process. Had insane shed. (Min/Fin/HRT)
The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.
community Taking HRT medication not only cured my thinning hair, it gave me better hair than I ever had before
Hormone replacement therapy with spironolactone and estradiol significantly improved hair thickness and growth, surpassing previous treatments like dutasteride, finasteride, and minoxidil. The user experienced regrowth in receded areas and a more youthful appearance.
community Dutasteride , bloodwork and dht.
The user reported high testosterone and estradiol levels within range, but unexpectedly high DHT levels after using finasteride and dutasteride for hair loss. Another person suggested the dutasteride might be fake or a bad batch and recommended using the branded Avodart.