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      community Anyone here used spirolactone/cyproterone acetate/bicalutamide?

      in Chat  4 upvotes 9 months ago
      The conversation discusses the use of spironolactone, cyproterone acetate, and bicalutamide for hair loss, with concerns about side effects like gynecomastia and depression. Topical spironolactone is considered safe for men and effective when combined with regular treatments.

      community Overwhelming amount of anti-androgens

      in Female 3 years ago
      The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

      community Low dose finestaride 6 month progress (0,25mg)

      in Progress Pictures  5 upvotes 2 months ago
      The user shared their 6-month progress using 0.25 mg finasteride, topical minoxidil, and dermastamping, noting good results but experiencing increased sleepiness. Another user suggested minoxidil might be causing the sleepiness, and the original poster considered adjusting their treatment.

      community Continue RU58841 or hair system for receding hair line?

      in Progress Pictures  9 upvotes 2 years ago
      A user is considering whether to continue using RU58841 or switch to hair system patches for a receding hairline, while already using finasteride, oral minoxidil, and microneedling. Another user suggests buying RU58841 in powder form to save money and notes the original poster's hair has significantly improved.

      community bicalutamide or spironolactone for fphl

      in Female  6 upvotes 3 years ago
      Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

      community Thoughts on Avixis Alfatradiol?

      in Product  4 upvotes 4 years ago
      Avixis Alfatradiol is a topical 5-alpha reductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.

      community Once daily topical Min, weekly 1.5 mm dermarolling

      in Progress Pictures  35 upvotes 2 years ago
      The user has been using 5% minoxidil once daily and microneedling with a 1.5 mm dermaroller weekly for three months, considering increasing minoxidil usage but avoiding finasteride due to libido concerns. Another person suggests considering other treatments like RU58841, alfatradiol, topical finasteride, clascoterone, or saw palmetto since not using a DHT blocker could be less effective.

      community Finasteride 5mg & Spironolactone 100mg

      in Female  2 upvotes 1 year ago
      A 20-year-old female is using finasteride 5mg and spironolactone 100mg for severe hirsutism and is experiencing minor side effects like water weight loss and irregular periods. She is concerned about potential future side effects and hair regrowth on her scalp.

      community Ru58841 2% ED 9 month progress

      in Progress Pictures  17 upvotes 3 years ago
      A user shared their 9-month progress using RU58841 at 2% daily for hair regrowth, initially starting at 5% but reducing the dose due to early signs of gynecomastia, which has since mostly resolved. They achieved their goal of regrowing hair at the temples and hairline.

      community Topical spironolactone — how much do you apply?

      in Female  3 upvotes 11 months ago
      A user with androgenetic alopecia is using 8 ml of 1.4% topical spironolactone solution daily but is unsure if this amount is excessive, as 2 ml is more typical. They seek advice on the appropriate amount to apply.

      community Rejected for the 2nd time for the VDPHL01 Clinical Trials (believe it or not!)

      in Chat  12 upvotes 1 year ago
      The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

      community (MTF 35) 20 Months Feminizing HRT

      in Transgender  18 upvotes 3 months ago
      A 35-year-old transgender woman experienced hair regrowth with feminizing HRT, adding dutasteride and bicalutamide, and plans a hair transplant for further improvement. Estrogen also improved skin appearance, and the user advises against cisgender men using feminizing HRT for hair regrowth.

      community Estrogen lowering supplements while on Finasteride?

      in Treatment  8 upvotes 4 years ago
      The conversation discusses using aromatase inhibiting supplements like DIM and Grape Seed extract while on finasteride for hair loss treatment. Users share their experiences and opinions on combining these supplements with finasteride.

      community RU58841 - How & When to Apply?

      in Product  4 upvotes 2 years ago
      RU58841 should be applied directly to the scalp, ideally once a day, a few hours before bed. Some users experienced side effects like shedding and systemic issues when using RU58841 and Minoxidil together, while others reported no side effects when using RU58841 alone.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 3 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community Will you try clascosterone when it gets released?

      in Treatment  14 upvotes 4 months ago
      People are interested in trying clascosterone (Breezula) for hair loss, especially those who are too young for finasteride. Some users express concerns about the cost and prescription requirements, while others discuss alternatives like RU58841.

      community Serenoa repens (Saw palmetto)

      in Chat  4 upvotes 3 months ago
      Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

      community Setipiprant/PGE2 feedbacks?

      in Question  4 upvotes 8 years ago
      The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.

      community *WOMEN* on Spironolactone - experiences?

       6 upvotes 10 years ago
      Hair loss treatments discussed: Minoxidil, Finasteride, RU58841, and Spironolactone. Woman with androgenetic alopecia and alopecia areata shares experience using Spironolactone.

      community cb-03-01 research chem (winlevi/clascoterone cream)

      in Technology  3 upvotes 2 years ago
      The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

      community 7 months progress nuclear stack

      in Update  129 upvotes 3 years ago
      A 7-month progress report of using finasteride and minoxidil, as well as keto dieting and derma stamping; the discussion also touched on RU58841 and its potential side effects.