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      community From 21 to 23 years old. What do you think?

      in Treatment  329 upvotes 2 months ago
      A user is using oral finasteride, oral dutasteride, and drinking topical minoxidil for hair loss, despite health warnings. Switching from finasteride to dutasteride did not improve hair density.

      community What do we currently know about clascoterone?

      in Chat  6 upvotes 2 months ago
      Clascoterone is seen as a promising topical treatment for hair loss, similar to finasteride but without side effects, though concerns exist about its long-term effectiveness. Other treatments discussed include topical minoxidil, ketoconazole, microneedling, and oral options like dutasteride and minoxidil.

      community Just started ru58841, ask me anything.

      in Research/Science  14 upvotes 2 months ago
      The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

      community RU-58441 Janoshik test result of Made-In-China Supplier

      in Product  28 upvotes 4 months ago
      A user ordered RU58841 from a Chinese supplier, found it to be less than 99% pure, and plans to try a different seller next time. Concerns were raised about impurities, but the user believes they are likely inactive fillers rather than harmful substances.

      community Almost 7 months of Topical Fin + Min

      in Progress Pictures  343 upvotes 4 months ago
      A 24-year-old shared their 7-month progress using a topical solution of finasteride 0.1%, minoxidil 5%, and hydrocortisone butyrate 0.08%, along with ketoconazole shampoo, to treat hair loss, reporting no side effects and noticeable hair improvement. They also take vitamin D and biotin supplements, use a dermastamp, and manage Hashimoto's without thyroid medication.

      community It's so over. Im beyond cooked

      in Update 4 months ago
      The user is experiencing hair loss despite using Dutasteride and plans to try RU58841, considering adding Oral Minoxidil. They express frustration with diffuse thinning and seek advice on managing hair loss.

      community Natural methods only. Gains or Nah?

      in Is this regrowth? 4 months ago
      The user is attempting to regrow hair using natural methods like microneedling, rosemary oil, and capsaicin tincture, avoiding medications like finasteride and minoxidil due to past health issues. Feedback suggests these methods are ineffective, with many recommending shaving or considering a hair system instead.

      community Is it a good idea to add RU58841 to finasteride? (No min)

      in Treatment  6 upvotes 5 months ago
      The user has been using finasteride for a year to stop hair loss and is considering adding RU58841 instead of minoxidil to further inhibit DHT. Another user suggests adding dutasteride for better DHT inhibition, but the original user cannot access it and is considering RU58841 despite potential side effects.

      community 2 months in my regrowth journey

      in Progress Pictures  13 upvotes 6 months ago
      The user is using finasteride, topical minoxidil, derma rolling, ketoconazole shampoo, and multivitamins for hair regrowth. They also drink topical minoxidil due to the unavailability of oral minoxidil, despite concerns from others about safety.

      community I use the big 4 to combat but I need to do more

      in Minoxidil  3 upvotes 6 months ago
      The conversation discusses various hair loss treatments, including Minoxidil, Finasteride, Dutasteride, Ketoconazole shampoo, microneedling, and supplements like collagen, biotin, and vitamins. Users suggest additional treatments like red light therapy, scalp massages, and possibly adding RU58841 or Tretinoin.

      community I think microneedling before topical application of finasteride (or dut) is a path we should investigate (for those of us who don't care about systemic absorption). Here's why...

      in Microneedling  21 upvotes 7 months ago
      Microneedling before applying topical finasteride or dutasteride may enhance their effectiveness by increasing local absorption in the scalp, despite concerns about systemic absorption. Users discuss combining this method with oral treatments and minoxidil, noting potential benefits and side effects.

      community Don't use PP405 from everychem. it is likely fake.

      in Research/Science  67 upvotes 9 months ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation?

      in Treatment  13 upvotes 9 months ago
      Non-steroidal ways to reduce scalp inflammation include using topical melatonin, urea shampoo, Zyrtec, turmeric with black pepper, omega-3 supplements, a self-made topical solution with cetirizine, melatonin, and piroctone olamine, ketoconazole shampoo, witch hazel shampoo, tacrolimus, and lifestyle changes like a healthy diet and regular exercise. Some users also mentioned unconventional methods like infrared light therapy and a carnivore diet.

      community Topical Finasteride 2 year update

      in Progress Pictures  934 upvotes 10 months ago
      The user reported significant improvement in hair quality and stability using topical finasteride for two years, without side effects. They later added minoxidil, which may have further enhanced hair quality.

      community Those that apply minoxidil twice a day

      in Chat  71 upvotes 11 months ago
      Minoxidil is typically applied once daily, with some users opting for foam to minimize irritation. Users often combine it with finasteride or use oral minoxidil for improved results, while managing scalp irritation with ketoconazole or salicylic acid shampoos.

      community Switching to Oral from Topical min effective or not

      in Minoxidil  6 upvotes 11 months ago
      Switching from topical to oral minoxidil may lead to better results for some users, with oral minoxidil generally being more effective due to higher absorption. However, it can also cause side effects like hypertrichosis and blood pressure issues, and individual responses may vary.

      community Minoxidil is destroying my scalp - please help

      in Minoxidil  128 upvotes 1 year ago
      Minoxidil is causing severe scalp irritation, including itchiness and dryness, for the user. Alternatives suggested include anti-fungal treatments, propylene-glycol-free formulations, and possibly oral minoxidil.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.