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      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community Does anyone else feel that the hype for PP405 has gone?

      in Chat  25 upvotes 1 month ago
      The conversation discusses skepticism and diminishing excitement around the hair loss treatment PP405 due to unclear trial results. It also mentions other treatments like finasteride, minoxidil, VDPHL01 (extended-release minoxidil), and GT20026 as potential options for hair loss management.

      community Retinol from the ordinary for minoxidil

      in Minoxidil  2 upvotes 2 years ago
      Retinol or tretinoin may improve minoxidil absorption and effectiveness. The user is considering using The Ordinary's 1% retinol as tretinoin is hard to get in their country.

      community Best minoxidil formulation for best results?

      in Minoxidil  2 upvotes 1 year ago
      The conversation discusses creating a customized minoxidil formulation with tretinoin, azelaic acid, and caffeine, but there are concerns about foam stabilization due to acidity. The user seeks advice on the best formulation for effective results.

      community Can valisone solution cause hairloss?

      in Question  1 upvotes 7 years ago
      A user is concerned that prolonged use of valisone (betamethasone) and clotrimazole solution for scalp dermatitis may be causing hair thinning and loss. They noticed thinning in the area where the solution was applied.

      community Simple to add GHK-Cu to RU58841?

      in Product  1 upvotes 1 year ago
      The conversation is about a user seeking advice on adding GHK-Cu to RU58841 for hair loss treatment, while already using oral minoxidil, dutasteride, ketoconazole shampoo, and considering LLLT. They are unsure about the concentration and carrier solution for GHK-Cu.

      community 58M: Nizoral Stopped Working for Scalp Itching, Alternatives?

      in General  100 upvotes 8 months ago
      A 58-year-old uses finasteride for hair loss and has tried various shampoos, finding Equate T-gel effective for controlling itching. Nizoral was previously effective but no longer works, and DermaKB hasn't been used long enough to assess its effectiveness.

      community Realistically, how much PP405 will cost?

      in Treatment  27 upvotes 1 year ago
      PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.

      community Is stemoxydine (serioxyl advanced) toxic/lethal to cats?

      in Chat  1 upvotes 1 year ago
      The conversation is about concerns regarding the safety of using stemoxydine (Serioxyl Advanced) around cats, with the user also using minoxidil, oral minoxidil, dutasteride, and microneedling for hair loss. The user is seeking advice on whether stemoxydine is toxic or lethal to cats.

      community Blood work after 4 month topical fin/min

      in Update  6 upvotes 1 year ago
      After 4 months of using topical finasteride and minoxidil, blood tests showed increased E2, Test, and Prolactine levels. The user is concerned about potential side effects like gyno and is seeking advice on managing these values.

      community Pp405 - it has to work. It has to.

      in Research/Science  170 upvotes 3 months ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community Homemade fin - solubilization issue

      in Treatment  1 upvotes 3 years ago
      The user is attempting to create a topical finasteride solution by mixing crushed finasteride pills with minoxidil but is facing solubility issues. They are unsure if the finasteride has dissolved properly and are seeking advice on whether it is safe to use and if there is a solution to the problem.

      community Quit Minoxidil, keep gains w/ Fin and Stemoxydine? | Self-experiment

      in Minoxidil  52 upvotes 3 years ago
      A user experimenting with quitting using Minoxidil and replacing it with Finasteride and Stemoxydine in order to keep hair loss gains, but other users warning the original poster of potential shedding. Another user suggested phasing out Minoxidil and replacing it with Finasteride and microneedling instead.

      community Going to inject NAD+ and GHL-Cu into Scalp for a few months

      in Chat  1 upvotes 8 months ago
      The conversation discusses a user's plan to inject NAD+ and GHK-Cu into their scalp to improve hair health, with concerns raised about the risks of infection and necrosis. Alternatives like finasteride, dutasteride, microneedling, oral minoxidil, and scalp massages are suggested.

      community Unexpected temple hair growth from GHK-Cu

      in Update  23 upvotes 5 months ago
      GHK-Cu injections led to unexpected temple hair growth for someone who had been using minoxidil and finasteride for over a decade. The user plans to continue using GHK-Cu and experiment with a DIY AHK-Cu serum.

      community Great gains on 500mg fin and 1000mg min everyday

      in Satire  768 upvotes 11 months ago
      The conversation humorously discusses exaggerated hair growth results using 500mg finasteride and 1000mg minoxidil daily, with side effects including a bloody nose and lowered libido. It also jokes about microneedling, hair transplants, and elephants, suggesting the post is satirical.

      community The end of minoxidil and fin/dut regime

      in Research/Science  106 upvotes 2 months ago
      New hair loss treatments like GT20029 and PP405 could potentially replace minoxidil and finasteride, offering better results with fewer side effects. However, current treatments like finasteride and minoxidil are still effective for many, despite concerns about side effects.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.