KX-826/pyrilutamide is undergoing an additional one-year safety and efficacy trial in China after a six-month study. Some participants speculate on the reasons for the extended trial and discuss the potential of other treatments.
Finasteride and minoxidil are recommended as first-line treatments for hair loss, with dutasteride and oral minoxidil as stronger options if needed. Hair transplants should only be considered after achieving stability with medication, and non-surgical options are suggested if medications are ineffective.
A user shared their pre-finasteride lab results, including DHT, estradiol, testosterone, SHBG, prolactin, FSH, and LH levels. Another user responded, cautioning against making unsupported claims about side effects and recovery.
The user is using minoxidil and recently started fluridil for mild hair loss and is questioning if this treatment is sufficient without finasteride. They have finasteride available but prefer not to use it.
An 18-year-old male is experiencing significant hair shedding, particularly from the back of his head, despite normal blood test results except for slightly low vitamin D. A dermatologist prescribed minoxidil for receding temples, but the cause of the shedding remains unclear.
The conversation discusses using Botox to treat male pattern baldness, suggesting it may promote hair growth by increasing scalp blood flow and oxygen, reducing dihydrotestosterone levels. The user wonders why this treatment is not widely discussed or if it has been discredited.
The user is experiencing hair regrowth using oral minoxidil, finasteride, dermastamping, and ketoconazole shampoo. Suggestions include adding pyrilutamide or considering dutasteride instead of finasteride.
A 26-year-old man shared his positive results after 10 months of treating male pattern baldness using a regimen that includes Estradiol Enanthate, DHPA, Bicalutamide, Dutasteride, oral and topical Minoxidil, and a dermaroller. He experienced mild gynecomastia and reduced body hair as side effects but was satisfied with the outcome.
The conversation discusses the difference between the commercially available Pyrilutamide and the version in clinical trials. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.
Users discuss finding reliable sources for RU58841, focusing on lab tests, batch consistency, and community reputation. Some mention using alternatives like pyrilutamide.
User experienced good results with topical finasteride, noting reduced DHT and increased testosterone. They plan to revert to a lower dosage after observing slight libido reduction.
The user successfully managed hair regrowth by using a combination of finasteride, dutasteride, minoxidil, and specific shampoos to treat seborrheic dermatitis. They emphasize the importance of maintaining a healthy scalp and are considering food intolerance tests to further address inflammation.
A 43-year-old male with advanced hair loss is experimenting with alternative treatments, including red light therapy, microneedling, scalp massages, an oil mix, and ketoconazole shampoo, after previously experiencing side effects from finasteride and minoxidil. He noticed some minor changes with red light therapy but remains skeptical about significant improvement.
A 24-year-old with a history of hair loss, low testosterone, and other health issues is seeking advice on treatments. They are considering options like topical and oral finasteride, oral minoxidil, PRP therapy, tretinoin, and microneedling.
A user experienced significant hair shedding after starting dutasteride, questioning if it's due to the treatment or rapid progression of androgenetic alopecia. They previously used Rogaine and biotin for over 10 years.
The conversation is about finding a source for Alfatradiol 0.1% as most available products are 0.025%. A suggestion was made to use four times the dosage of the 0.025% product.
A user discussed a significant hair recovery using alfatradiol and fluridil but was considered untrustworthy and the post was deleted. They are seeking the original poster's username.
A 31-year-old man with androgenic alopecia is considering treatments like finasteride, minoxidil, and ketoconazole shampoo but is worried about finasteride's side effects. Users recommend starting with finasteride or dutasteride for DHT blocking, suggesting topical solutions to reduce side effects.
The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.
ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.
The user has been experiencing prolonged hair shedding despite using Dutasteride, Minoxidil, and topical Finasteride, with blood tests showing high free testosterone and low SHBG. Suggestions include adjusting Minoxidil dosage, considering topical anti-androgens like RU58841, and addressing metabolic factors to increase SHBG.
The conclusion of the conversation is that the user, AlgomasReturns, tried various treatments for hair loss but saw regrowth after starting finasteride. They recommend others to try it as well.
The conversation humorously discusses the complexity of understanding and treating male pattern hair loss, mentioning treatments like Minoxidil, finasteride, RU58841, Dr. Brotzu's lotion, and Dr. Tsuji's hair cloning. The original post satirically claims that only those with high intelligence can appreciate these treatments.
Many users experienced increased diffuse thinning after starting finasteride, with some switching to dutasteride or adding minoxidil in hopes of improvement. Thyroid issues and low ferritin levels were also discussed as potential factors affecting hair loss.
KX-826 Phase II results show that a 0.5% concentration performs better than 1% for treating male pattern baldness. Concerns about receptor upregulation from long-term DHT antagonism were mentioned.
A 24-year-old male has been using oral Finasteride 1mg/day for 6 months and nanoxidil for 10 months, recently switching to oral Minoxidil 2.5mg daily, with no progress. Suggestions include getting a scalp biopsy, consulting a dermatologist, and possibly trying higher doses of oral Minoxidil or switching to dutasteride.
A monoclonal antibody clinical trial for potential hair loss treatments in Victoria, Australia and the discussion of their efficacy. People shared information about similar drugs already on the market, speculated about potential side effects, and discussed how to spread the word about the trial.
The user is seeking a doctor to prescribe finasteride for a receding hairline and thin hair, considering using minoxidil and supplements as well. Suggestions include using telehealth services or local doctors for prescriptions and exploring non-surgical treatment options with dermatologists.