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      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  90 upvotes 5 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Alfatradiol 1% study rebuttal.

      in Research/Science  4 upvotes 2 years ago
      Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.

      community minoxidil on eyebrows feedback

      in Female  4 upvotes 2 years ago
      A female user is seeking feedback on using topical minoxidil on eyebrows due to eyebrow loss, as oral minoxidil hasn't worked and they avoid Latisse due to potential fat loss.

      community Starting Maxogen-X and want to share progress

      in Treatment  3 upvotes 3 years ago
      The conversation is about using Maxogen-X, a topical solution containing minoxidil, finasteride, tretinoin, and azelaic acid, for hair loss treatment. Users discuss their experiences, including initial shedding and the hope for thicker hair, while sharing progress updates.

      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  258 upvotes 1 year ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community I am about to cry, umI hate my gens

      in Chat  58 upvotes 9 months ago
      Hair loss affects confidence, with discussions on treatments like finasteride, minoxidil, and RU58841. Emphasis is placed on self-acceptance and building confidence beyond appearance.

      community 4600 - result 9 month - Dr. Carman

      in Progress Pictures  254 upvotes 2 years ago
      A user shared their 9-month post-hair transplant results with 4600 grafts, using only Nourkin hair vitamins, Vitamin D, and B12, and expressed satisfaction. The replies debated the necessity of medications like finasteride and minoxidil for maintaining hair health.

      community Tretinoin absorption Minoxidil

      in Treatment  2 upvotes 2 years ago
      Tretinoin may help more minoxidil convert to its active form and could potentially increase its absorption, raising concerns about safety if too much enters the bloodstream. It's unclear if tretinoin affects finasteride absorption.

      community Oral minoxidil in EU (hair is law)

      in Minoxidil  6 upvotes 1 week ago
      The conversation is about finding a reliable source for oral minoxidil in the EU, as the original supplier is out of stock. The user is currently using finasteride and oral minoxidil for hair loss treatment.

      community microneedle, any long term users damage?

      in Microneedling  35 upvotes 1 year ago
      Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

      community 6 month update fin, min, micro-needle

      in Progress Pictures  436 upvotes 11 months ago
      The user experienced significant hair regrowth and improved hair quality after six months of using oral minoxidil, finasteride, and micro-needling. They reported increased libido initially but no other side effects, and they plan to continue the treatment.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community Unused Eucapil- anyone want it?

      in Product  1 upvotes 1 year ago
      The conversation is about a user offering free unused Eucapil after switching to finasteride for hair loss treatment. The user did not use Eucapil and is willing to give it away locally or ship it if costs are covered.

      community Another transplant or SMP? (Not balding)

      in Transplants  23 upvotes 3 months ago
      The user is considering another hair transplant or scalp micropigmentation (SMP) for a congenital bald spot, but previous transplants were less effective due to scar tissue. Suggestions include using hair fibers, changing hairstyles, or doing nothing, as the spot is not very noticeable.

      community My kotoconazole shampoo contain this

      in Ketoconazole 1 month ago
      The conversation discusses the safety and use of ketoconazole shampoo for hair loss, with mentions of zinc pyrithione and selenium sulfide. Users debate the safety of these ingredients, particularly zinc pyrithione, and share opinions on regulatory differences between Europe and the US.

      community Retin-a (tretinoin) increase effect of minox

      in Minoxidil  27 upvotes 6 years ago
      The conversation discusses how applying topical tretinoin for 5 days can convert 43% of individuals who initially do not respond to minoxidil into responders, enhancing the effect of minoxidil on hair growth. Specific treatments mentioned are minoxidil and tretinoin.

      community When do we hear about Pelage February 2025 study results?

      in Technology  14 upvotes 1 year ago
      The conversation is about the anticipated results of Pelage's Phase 2a clinical trial for their topical hair loss treatment, PP405. Users speculate on when the results will be available, noting that delays might indicate less successful outcomes.

      community Case study: 1mo progress microneedling + minox, no fin.

      in Microneedling  8 upvotes 5 years ago
      A user shared their experience with microneedling and minoxidil for hair loss, avoiding finasteride due to concerns about systemic hormone effects. They reported slight hair regrowth after one month and plan to continue the regimen, noting improvements in skin sensitivity and managing dandruff with anti-dandruff shampoo.

      community 3.5-4 month progress is this hyper response?

      in Progress Pictures  29 upvotes 1 year ago
      A user shared their 3.5-4 month progress using Topical Minoxidil, Oral Finasteride, Keto 1%, and Dermastamp, reporting positive results despite some shedding and flaking. Replies praised the progress and inquired about the treatment routine and temple condition.