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      community Am I crazy or is this recovery?

      in Is this regrowth?  134 upvotes 1 year ago
      The user is experiencing sudden hair loss and is considering micro-needling, low-level light therapy, iron supplements, folihair, and Omega 3. They are hesitant to start finasteride, suspecting the hair loss might be due to telogen effluvium from a past COVID-19 infection.

      community Could RU58841 actually worsen hairloss?

      in Treatment  2 upvotes 1 year ago
      The user experienced worsening hair density after using finasteride, dutasteride, and RU58841, suspecting RU58841 might be the cause. They are considering stopping RU58841 after a scalp biopsy, while others share mixed experiences with RU58841's effectiveness.

      community Why do so many people trash on finasteride?

      in Chat  247 upvotes 1 year ago
      Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

      community It has been 1 year. Should I keep going or give up?

      in Is this regrowth?  6 upvotes 1 year ago
      The user is considering whether to continue their hair loss treatment, which includes finasteride, minoxidil spray, keto shampoo, and dermarolling. Suggestions include increasing minoxidil application, adding multivitamins, improving sleep, and possibly switching to dutasteride, while the consensus is to keep going with the treatment.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  49 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Wtf have we been doing for the last 30 years

      in Treatment  548 upvotes 1 year ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

      community Has any premature balding guys actually saved and maintained their hair?

      in Chat  17 upvotes 1 year ago
      A user discusses their struggle with aggressive hair loss starting at a young age and their use of various treatments, including topical finasteride, minoxidil, dutasteride, and RU58841, without significant success. Other users share their experiences and suggest trying oral finasteride or dutasteride, topical spironolactone, and maintaining a vitamin regimen, while noting potential side effects like gynecomastia.

      community Ultimate Stack without nuking your gender (you'll go broke)

      in Treatment  85 upvotes 1 year ago
      A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

      community any Ru58841 user ? + What do I need to expect?

      in Product  10 upvotes 1 year ago
      The user is considering adding RU58841 to their current hair loss treatment of finasteride and minoxidil, but is concerned about potential side effects like hairline recession and shedding. Some users report positive results with RU58841, while others experience side effects such as chest pain and dizziness.

      community Are permanent hair gains even possible?

      in Chat  13 upvotes 1 year ago
      Hair regrowth from treatments like minoxidil, RU58841, and finasteride is not permanent; stopping these treatments typically results in hair loss resuming. Beard hair can become permanent with minoxidil use, unlike scalp hair, which requires ongoing treatment to maintain gains.

      community Anyone else realize how many younger guys are balding?

      in Chat  262 upvotes 1 year ago
      Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

      community HT / Meds results are reverting, thinning, crazy shedding..

      in Progress Pictures  164 upvotes 1 year ago
      A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community MY 6 MONTH TRANSFORMATION PROGRESS

      in Progress Pictures  210 upvotes 1 year ago
      A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.

      community 1 Year on just Fin 1mg 3 times/week

      in Progress Pictures  839 upvotes 1 year ago
      A user shared their one-year progress using finasteride 1mg three times a week, starting at age 25, with noticeable regrowth after three months and no side effects. Other users discussed their experiences with finasteride, minoxidil, microneedling, and dutasteride, noting varying results and side effects.

      community Can anyone confidently say their erections are the same on fin ?

      in Chat  240 upvotes 1 year ago
      The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.

      community blood DHT levels shot up after doubling dutasteride dosage

      in Finasteride/Dutasteride  20 upvotes 1 year ago
      A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

      community Why is there so many people claiming Dutasteride destroyed their hair?

      in Chat  25 upvotes 1 year ago
      Some people claim Dutasteride worsened their hair loss, causing concern among users. Reasons suggested include initial shedding phases, incorrect attribution to Dutasteride when other factors are involved, genetic variations affecting drug response, and the possibility of non-authentic medication.

      community 15 years of finasteride/minoxidil

      in Update  194 upvotes 1 year ago
      A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

      community Any other celebrities known to be taking finasteride ?

      in Finasteride/Dutasteride  455 upvotes 1 year ago
      The conversation discusses various celebrities who reportedly use hair loss treatments like finasteride and dutasteride. Users share their experiences and opinions on starting treatment, with some encouraging the original poster to consult a dermatologist and consider treatment before it's too late.

      community Just started RU a month ago after being on fin and min for almost 3 years. Progress so far: My temples were pretty bare before this. Really hoping at least some of these become terminal.

      in Is this regrowth?  393 upvotes 2 years ago
      A user started using RU58841 a month ago after using finasteride and minoxidil for nearly three years, hoping for hair regrowth at the temples. Other users suggest vitamin B supplements and microneedling to improve hair thickness, and one mentions the possibility of a hair transplant for the temples.