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      community How long should you take fin/dut for, before getting a transplant?

      in Finasteride/Dutasteride  14 upvotes 2 years ago
      The user started taking dutasteride a month ago and is seeking advice on whether to wait for a year before getting a hair transplant, as it could potentially strengthen the donor-zone and require fewer grafts, or to get a transplant immediately, extracting only the "strong hairs" not affected by dutasteride. The user is unsure which approach is correct.

      community Debunking Androgenetic Theory (Hair Transplants)

      in Research/Science  25 upvotes 2 years ago
      The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

      community 4 months running still lot to improve ig 😉

      in Progress Pictures  481 upvotes 2 years ago
      A 20-year-old who started balding in 2020 and has been using a treatment routine for 4 months that includes daily Minoxidil (1.5ml), Finasteride three times a week, and a derma roller twice a week, along with a 2-month course of vitamin supplements. The treatment has significantly improved their hair loss, boosting their confidence.

      community Experience with Spironolactone?

      in Female  7 upvotes 4 years ago
      Spudlady asks about experiences with spironolactone for hair loss. She has lost hair due to stress and seeks ways to stop shedding.

      community Dry and itchy scalp after ru58841 and keto. Advice needed

      in Product  3 upvotes 4 years ago
      The user experienced severe scalp itching after using RU58841 and ketoconazole shampoo, despite trying moisturizing treatments. They suspect the issue is related to the propylene glycol in the vehicle and are seeking alternatives.

      community SAFFLOWER OIL good alternative for Minoxidil?

      in Treatment  1 upvotes 6 years ago
      Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

      community a new supplement just released

       11 upvotes 8 years ago
      A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

      community Some Questions Regarding FUE Hair Loss Surgery

      in Transplants  5 upvotes 9 years ago
      The conversation discusses FUE hair transplant surgery, including questions about donor area recovery, success rates, precautions, hair growth rate, and the safety of PRP injections. It also inquires about using hairpieces post-surgery.

      community A battle won?

       9 upvotes 10 years ago
      The user tried various treatments for hair loss, including finasteride, vitamins, Saw Palmetto, beta sitosterol, pumpkin oil, borage oil, stinging nettle, and emu oil. They recently noticed tiny black hairs, suggesting some improvement.

      community Chronostim: What is it and does it work?

       5 upvotes 12 years ago
      Chronostim is a hair treatment with separate day and night formulas containing ingredients like lauric acid, glycyrrhetinic acid, and piroctone olamine. Users discuss its effectiveness for hair loss.

      community Most promising cures for baldness as of May 2026

      in Treatment  56 upvotes 1 month ago
      PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

      community A less common type of hairloss case

      in Research/Science  4 upvotes 2 months ago
      High-dose Lysine and Histidine supplements caused curly/kinky hair and shedding due to Elastin dysfunction. Minoxidil, white tea, and dark grape juice were mentioned as treatments to inhibit Elastase and mimic Lysyl Oxidase.

      community I'm becoming non-responder to minoxidil. What's going on?

      in Minoxidil  7 upvotes 10 months ago
      The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.

      community Musely s Exosome formulation looks interesting

      in Chat  13 upvotes 1 year ago
      Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.

      community can saw palmetto help me even a little bit (17m)

      in Treatment  6 upvotes 1 year ago
      A 17-year-old is considering using saw palmetto for hair loss until they can get finasteride, while currently using minoxidil and ketoconazole. Users suggest that saw palmetto is weak, and recommend continuing minoxidil and ketoconazole until finasteride is available.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.