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      community Is this broscience? From More Plates, More Dates

      in Research/Science  21 upvotes 2 years ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

      community When could we expect pp405 to hit the market?

      in Research/Science  31 upvotes 11 months ago
      PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.

      community Finastride only ! user for 4.5 years

      in Progress Pictures  38 upvotes 11 months ago
      A 26-year-old male has been using finasteride for 4.5 years to maintain hair and recently started taking dutasteride weekly due to increased hair shedding. He plans to gradually switch to dutasteride while monitoring side effects and hair changes.

      community My Experience and a Discourse on "DUPA"

      in Treatment  8 upvotes 1 year ago
      The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

      community 2 year anniversary of Fin only - M48

      in Is this regrowth?  212 upvotes 1 year ago
      A 48-year-old man has been using finasteride at 1mg three times a week for two years, seeing some hair regrowth but noting lighting affects appearance. He is considering adding minoxidil but is concerned about shedding.

      community Groundbreaking complete hair regrowth wonder drug found!!!

      in Satire  914 upvotes 9 months ago
      A satirical post humorously discusses a fictional hair regrowth drug called PP405, with users joking about its effectiveness and bizarre presentation. The conversation includes humorous reactions and references to the absurdity of the content.

      community Thinking about using PP405 and RU58841

      in Research/Science  1 upvotes 3 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community M29 - 4 YEARS on Dutasteride - almost no progress

      in Chat  6 upvotes 2 months ago
      The user has been on a comprehensive hair loss treatment regimen for four years, including Dutasteride, topical and oral Minoxidil, and various other treatments, but has seen little progress and is considering a hair transplant. Despite trying multiple therapies, including PRP and exosome injections, the user is still experiencing hair thinning and is hesitant about trying peptides due to potential cancer risks.

      community Switching from Finasteride to RU58841?

      in General  168 upvotes 6 months ago
      The user experienced severe side effects from finasteride, including cognitive and sexual issues, despite its effectiveness for hair growth. They are considering switching to RU58841 and seek insights from others who have made a similar change.

      community Giving up on ever feeling comfortable in my body

      in Update  79 upvotes 4 years ago
      The user has been using finasteride, dutasteride, and RU58841 for hair loss without success and feels extremely uncomfortable with their appearance, including being bald and short. They express deep unhappiness and social isolation. Suggestions from others include adopting stoicism, focusing on personal development, considering a hair system, improving fashion, working out, and seeking therapy for mental health.

      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 9 months ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community Finasteride FTM experiences after being on T for 2+ years?

      in Transgender  8 upvotes 2 years ago
      People are discussing experiences with finasteride for hair loss after being on testosterone for over two years. Users report varying results, with some experiencing regrowth and no side effects, while others emphasize the importance of starting treatment early to prevent further hair loss.

      community Dr. Bloxham Verteporfin Update #5

      in Research/Science  80 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. It also mentions an update on Dr. Bloxham's Verteporfin treatment.

      community Verteporfin (Visudyne) group buy 🌷

      in Treatment  29 upvotes 4 years ago
      User seeks participants for Verteporfin group buy. Verteporfin, FDA approved, may regenerate hair follicles and sweat glands through heavy microneedling.

      community My Finasteride Story (Pictures + Blood work + Updates)

      in Finasteride  10 upvotes 7 years ago
      A user shared their experience with finasteride for hair regrowth, which was effective but caused side effects like gynecomastia and mood swings. They now manage side effects with Arimidex and vitamins while continuing finasteride, and monitor their health with blood tests.

      community Update on PP405 Trails - Pelage

      in Research/Science  14 upvotes 2 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community DUPA / APHK discussion ( Diffuse unpatterned alopecia / Acquired Progressive Hair Kinkering )

      in Treatment  3 upvotes 6 years ago
      The user discusses their experience with diffuse unpatterned alopecia and acquired progressive hair kinkering, noting improvements with treatments including biotin, pantothenic acid, finasteride, ketoconazole, and zinc pyrithione shampoo. They report thicker, healthier hair and improved scalp condition, attributing success mainly to biotin, pantothenic acid, and finasteride.

      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  289 upvotes 4 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community Natural methods of reversing MPB

       5 upvotes 6 years ago
      The conversation discusses natural methods for addressing male pattern baldness, with the original poster using a plant-based diet, herbs, scalp massages, pumpkin seed oil, and dermapen treatments, while avoiding pharmaceuticals like minoxidil and finasteride due to concerns about side effects. Other users suggest that pharmaceuticals like finasteride may be necessary for significant hair loss, but the original poster remains committed to natural approaches.

      community Here's a recommended bloodwork panel before starting Fin.

      in Finasteride  12 upvotes 9 years ago
      The conversation provides a detailed list of blood tests recommended before starting finasteride to establish a baseline for monitoring potential side effects. A shorter list is also provided for those with limited funds, and the user shares personal experience of using finasteride without issues for about nine years.

      community Anyone who used RU58841 without fin/dut?

      in Product  1 upvotes 1 year ago
      RU58841 was used by some for hair loss, but concerns about side effects like gynecomastia and safety were raised. Alternatives like finasteride, minoxidil, pyrilutamide, and alfatradiol were discussed, with some users reporting better experiences with these treatments.