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      community Oxytocin, empathy, hair, and cinnamon

      in General  138 upvotes 1 year ago
      Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.
      Doctor prescribed dut, not sure if they were correct

      community Doctor prescribed dut, not sure if they were correct

      in Treatments  120 upvotes 7 months ago
      The user is concerned about using dutasteride for potential hair loss, fearing it might accelerate balding if not effective. They are unsure about the doctor's diagnosis and are considering starting with finasteride instead.
      Sudden Triangular Thinning Patch

      community Sudden Triangular Thinning Patch

      in General  157 upvotes 7 months ago
      A 31-year-old has been using finasteride, dutasteride, and oral minoxidil for hair loss. They noticed a sudden triangular thinning patch on their scalp and are seeking advice, questioning if it could be medication-related.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  451 upvotes 1 year ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community What should i do while waiting

      in General  143 upvotes 4 months ago
      The user is seeking advice on preserving hair follicles at Norwood stage 6 or 7 while waiting for new treatments. They are considering using treatments like Minoxidil, finasteride, or RU58841.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Finasteride solution changing colors

      in Finasteride/Dutasteride  1 upvotes 1 week ago
      A user noticed a color change in their hair loss solution containing minoxidil, finasteride, retinoic acid, and hydrocortisone after storing it for several months. They are concerned about the effectiveness of the solution due to potential oxidation.

      community Losing progress on 1 mg Fin and 5 mg minoxidil

      in Progress Pictures  73 upvotes 1 week ago
      The user experienced initial hair regrowth with 1 mg finasteride and 5 mg minoxidil but began shedding after 4-5 months, which others suggest is common and may lead to thicker regrowth. Users recommend patience, as results can take up to 12-24 months, and suggest considering specialized clinics for hairline design if unsatisfied with medication alone.

      community Progress pics April 30 to Aug 9

      in Progress Pictures  302 upvotes 2 years ago
      The user "mspamnamem" shares their progress with a hair loss treatment stack consisting of finasteride, minoxidil, biotin, and microneedling. They express satisfaction with their progress and hope for continued improvement. Other users in the conversation provide encouragement and share their own experiences.

      community What should i do: 7 months on oral fin/min, shedding

      in General  99 upvotes 11 months ago
      The conversation is about hair loss treatments, specifically oral finasteride (1.2mg) and oral minoxidil (3mg), and the user's concern about increased shedding and brittle hair after 7 months of use. It is suggested that shedding is common and may be influenced by stress, and switching to dutasteride might help, but patience is advised as results can take up to a year.

      community Long term minoxidil as a permanent solution

      in Minoxidil  26 upvotes 4 years ago
      A user is considering using minoxidil for hair loss and asks for advice on application and long-term effectiveness. Responses suggest minoxidil can be effective but may lose efficiency over time, and combining it with other treatments like finasteride might be more beneficial.

      community Warning: Your Rogaine Foam Might Not Contain Minoxidil

      in Minoxidil  373 upvotes 1 year ago
      A user experienced significant hair loss after using Rogaine foam purchased from Amazon, which failed a bleach test for Minoxidil. They discovered that even legitimate Rogaine products might be faulty and advised buying from reputable sources.

      community 3 Month Finasterid and Minoxidil

      in Is this regrowth?  828 upvotes 6 months ago
      A 30-year-old experienced significant hair regrowth in three months using 1 mg of finasteride daily and 4 drops of 5% oral minoxidil solution, despite potential shedding and side effects like increased body hair. They also quit smoking, which may have contributed to the positive results.

      community How an SSRI seemed to help my hairloss

      in Chat  6 upvotes 3 years ago
      An SSRI (paroxetine) reduced hair loss and itching for a user with male-pattern baldness, but liver issues forced discontinuation, leading to increased hair loss and anxiety. The user plans to try other anti-anxiety medications, noting stress and anxiety significantly impact hair loss.

      community Any long term positive experiences with just minoxidil plus a dermaroller?

      in Minoxidil  10 upvotes 3 months ago
      Minoxidil and dermarolling can yield positive hair growth results, but long-term effectiveness varies, and some users experience hair loss again without additional treatments like finasteride. Microneedling enhances minoxidil's effectiveness by increasing enzyme activity, but individual experiences differ.

      community 100 Day Progress & Managing Realistic Expectations (FTM 24)

      in Progress Pictures  96 upvotes 3 months ago
      A trans man experiencing hair loss after starting testosterone treatment has seen positive results using topical minoxidil and finasteride, though his hair remains thin. He is considering continuing his current treatment and exploring additional options like microneedling and Breezula, while acknowledging the impact of testosterone on hair loss.

      community Oral minoxidil timeframe (any late responders)

      in Minoxidil  34 upvotes 4 months ago
      Oral minoxidil, finasteride, and dutasteride are being used to treat hair loss, but results are limited, leading to consideration of a hair transplant. The user plans to continue medication for another year before deciding on further action.

      community How much DHT causes hair loss ?

      in Finasteride/Dutasteride  2 upvotes 5 months ago
      The user is taking 2.5 mg dutasteride and 5% minoxidil but is not seeing hair regrowth, and is considering adding RU58841. They are experiencing fatigue and low MCV/MCH, possibly related to dutasteride, and are advised to be patient, consider microneedling, and check for iron deficiency.

      community Connection between finasteride and nafld?

      in Research/Science  4 upvotes 1 year ago
      Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.