PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stemcell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
A user is experiencing anxiety and insecurity about hair loss despite using finasteride for 19 months and oral minoxidil for 6 months. They are seeking advice on whether stress, scalp testosterone, or switching treatments could help, and are considering a buzzcut.
User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.
Fatty acid metabolic signaling can activate epithelial stemcells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.
Stemson Therapeutics announced a breakthrough in hair growth technology using stemcells. Users discussed the potential high cost and skepticism about the treatment's accessibility.
The conversation discusses unconventional and satirical ideas for hair regrowth, including using umbilical cord cells, stemcells, and other humorous suggestions. It concludes with recommendations for more traditional methods like hair transplants or hair systems.
Dr. Tsuji's stemcell hair multiplication procedure may offer a future solution for hair loss, but it is initially expected to be very expensive, with prices potentially decreasing over time. In the meantime, users discuss using treatments like finasteride, despite side effects, to manage hair loss.
User hoodoomoovoo discusses their interest in stemcell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.
The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. The user inquires if RENU Biogen is a DHT inhibitor.
PP405 shows promise in hair loss treatment, but stemcell therapy using adipose-derived stemcells and ATP also successfully reversed androgenetic alopecia in mice. Stemcell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.
The user experienced new hair growth after switching from oral finasteride to topical RU58841 with minoxidil and undergoing stemcell therapy. They noticed new hairs at the hairline and temples, but are unsure which treatment is responsible.
A user proposed genetically engineering scalp stemcells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.
Exosome treatment for hair loss, derived from umbilical cord stemcells, is being considered as an option before a hair transplant. Users discuss the need for ongoing maintenance and share experiences with different exosome sources, including plant-derived options.
User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.
A breakthrough in hair follicle cultivation using induced pluripotent stemcells (iPSCs) has been achieved, producing large hair follicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.
Stemcell and exosome injections for hair loss are discussed, with skepticism about their effectiveness and concerns about using non-genetically related stemcells. Dr. Deyarmin's treatments are mentioned, with some users questioning their legitimacy and others expressing curiosity.
A topical serum made from monounsaturated fatty acids showed rapid hair growth in mice within 20 days, but it remains experimental for humans. Users humorously discussed the frequent success of hair growth treatments in mice and expressed skepticism about translating these results to humans.
Applying minoxidil to eyelashes is unsafe due to potential eye irritation and chemical burns. Safer alternatives include peptide serums, castor oil, or lash lifts/extensions.
The user experienced facial puffiness after switching from finasteride to dutasteride, which they believe is due to dutasteride. They are seeking advice on reversing this effect, considering factors like diet, exercise, and potential hormonal changes.
Baldness is often preventable with treatments like dutasteride, oral minoxidil, or finasteride. Many people fail to address it due to misinformation or lack of commitment.
The user applied topical 0.1% finasteride and 5% minoxidil, along with weekly microneedling, resulting in significant hair regrowth. The user also lost 10kg through diet and exercise.
The conversation humorously acknowledges the role of mice in testing Minoxidil for hair loss while also discussing the ethics of animal testing. Some users argue against animal testing, citing cruelty, while others defend its necessity for medical advancements.
Minoxidil can cause facial bloat, which some users manage by adjusting sodium intake or using it only on the scalp. Alternatives like finasteride or dutasteride are suggested for those concerned about facial changes.
The user shared progress pictures after 5 months of using 1mg finasteride, weekly 1.5mm microneedling, and daily 2mg copper peptide injections. They discussed their hair loss treatment and results.
A user shared a nine-month hair regrowth progress using 5mg oral Minoxidil and 1.25mg oral Finasteride daily, with noticeable improvement and no side effects, despite a high-protein diet, occasional smoking, and regular exercise. They also mentioned using keto shampoo and having naturally increased body hair by about 10%.
A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.
A 28-year-old male on TRT with a family history of MPB reports that consuming 1-2 tbsp of virgin coconut oil daily reduces hair loss and improves hair condition. Stopping the oil leads to increased hair fall and dryness.
Excessive use of topical minoxidil led to unwanted facial changes and side effects. The user plans to switch to oral minoxidil with microneedling for hair regrowth.