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GT20029 shows promise as a topical treatment for hair loss, potentially replacing finasteride for some due to its low systemic exposure and ability to degrade androgen receptors. However, skepticism remains about its long-term efficacy and availability, with some users expressing doubt about new treatments consistently failing to reach the market.

The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.

A 26-year-old male shared progress pictures after 4 months of treating hair loss with finasteride (1.25 mg on Mondays, Wednesdays, and Fridays), topical minoxidil twice daily, ketoconazole shampoo twice weekly, and weekly microneedling at 1.5 mm. He is seeing hair growth improvement, especially in the front, and is considering hair grafts for the crown area if necessary for more density.

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

A 38-year-old male shared 5 months of hair loss treatment progress using oral finasteride, topical finasteride, topical minoxidil, microneedling, and supplements like biotin, zinc, saw palmetto, and pygeum. He is uncertain about the progress.

A user who has had success with 1 mg of finasteride and 2% keto shampoo used twice weekly, as well as other treatments such as oral minoxidil, spiro, and RU58841 potentially being considered in the future for further hair growth.

The user has experienced significant hair regrowth using finasteride, oral minoxidil, microneedling, keto shampoo, an LLLT helmet, vitamins, and supplements. They note progress but hope for further improvement in a specific area.

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

A user created a tracker for hair loss treatments in clinical development, including compounds like Dermaliq, RU58841, and Pyrilutamide. The tracker updates with new information and allows filtering by conditions like androgenetic alopecia (AGA) and alopecia areata (AA).

The user experienced increased hair shedding after using RU58841 for two months, but found relief from scalp itchiness. Other users shared similar shedding experiences and discussed side effects like joint pain, while also mentioning the use of finasteride and minoxidil.

The user experienced a second shedding phase at 7 months while using topical finasteride and minoxidil, which is considered normal. The second shedding phase typically doesn't last as long as the first.

A user experienced continuous hair shedding for six months after using topical 5% minoxidil and 0.1% finasteride. They switched to minoxidil gel and oral finasteride 1 mg due to scalp itchiness and are seeking advice on their situation.

PP405 shows promise for hair regrowth, with new hairs observed in 66% of patients in just 27 days. The discussion also mentions Minoxidil, finasteride, and RU58841 as potential treatments.

A user's progress after 3 months of using the "big 4" hair loss treatments - liposomal gel minoxidil, finasteride, keto shampoo and microneedling; with people providing advice about their own experiences and asking for more information.

The user is seeking an alternative solvent for pyrilutamide due to skin irritation from ethanol and propylene glycol. They experienced similar issues with topical minoxidil.

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

A 21-year-old user has been using finasteride 1mg daily since March 11 and ketoconazole 1% 2-3 times a week since April 22, with no significant side effects. They are questioning if they are seeing early hair regrowth after 2.5 months of treatment.

The user experiences heavy shedding after one year of using 1mg oral finasteride and twice-daily topical minoxidil, recently adding microneedling and daily Nizoral. They also take supplements like vitamin D and biotin.

The user is undergoing Mesotherapy and Low-Level Laser Therapy for hair loss, with plans for multiple sessions. They are also using oral finasteride, topical minoxidil, dutasteride, and hair fibers.

The conversation discusses using Ketozolin shampoo in Germany as an addition to finasteride and minoxidil for hair loss treatment. Users recommend applying a small amount 2-3 times a week, leaving it on for 5-10 minutes.

The user reports noticeable hair regrowth after using 2.5mg oral minoxidil daily and 2% ketoconazole shampoo every other day for three months. The dermatologist advised against finasteride due to the user's age but mentioned it might be needed later.

The conversation discusses combining topical cetirizine with minoxidil for hair loss treatment and inquires about the safety and absorption through the skin, as well as the possibility of adding melatonin.

Capilia Longa is considered as an alternative to Minoxidil for beard growth, with some users reporting positive results. However, concerns exist about its effectiveness and high cost, especially for scalp use.

The user has been using finasteride (1.25 mg oral) and minoxidil (5% topical) for 14 months, with recent addition of ketoconazole shampoo, and is experiencing ongoing hair shedding. Despite shedding, there is noticeable hair regrowth, though density remains a concern.

Low-Level Laser Therapy (LLLT) is seen as a safe and effective method for maintaining hair and promoting regrowth in androgenetic alopecia (AGA) and male pattern baldness (MPB), with devices like the HairMax LaserComb® and iRestore helmet being popular. Some users and professionals are skeptical about its long-term effectiveness and cost.

The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

The user shared progress pictures after 4 months of using topical finasteride, minoxidil, and Nizoral, noting significant hair improvement. They apply minoxidil once daily with a head massager and use 1% Nizoral 3-4 times a week, reporting no side effects.

The user is experiencing sudden hair loss and is considering micro-needling, low-level light therapy, iron supplements, folihair, and Omega 3. They are hesitant to start finasteride, suspecting the hair loss might be due to telogen effluvium from a past COVID-19 infection.

The conversation discusses the potential effectiveness and risks of using topical finasteride for hair loss, with considerations about using DMSO as a vehicle for application. Concerns are raised about DMSO's safety, absorption issues, and the systemic effects of topical finasteride.