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      community Temple regrowth, 5 months on fin + min

      in Progress Pictures  233 upvotes 1 month ago
      A trans man shared his 5-month progress using finasteride and minoxidil for temple regrowth, noting slow but steady results. Despite some negative comments, he received support and encouragement from others, with advice to start treatment early for best results.

      community A story about why it matters to fight this

      in Chat  47 upvotes 2 years ago
      A user shared their experience with hair loss treatments, including finasteride, minoxidil, and RU58841, which improved their hair from a diffuse NW3 to a solid NW2 - 2.5. They noticed significant changes in how people treated them after regrowing their hair, suggesting that attractiveness can greatly impact social interactions and opportunities.

      community Transition protocols from fin to dut

      in Chat  2 upvotes 1 month ago
      Transitioning from finasteride to dutasteride for hair loss, with suggestions to either slowly transition or frontload dutasteride. The user is also using minoxidil, nizoral, needling, and LLLT.

      community How well can HRT reduce scalp tension?

      in Transgender  6 upvotes 3 years ago
      A trans woman is curious about the impact of HRT on hair regrowth and scalp tension. Her current regimen includes finasteride, spironolactone, estradiol, ketoconazole, vitamin D, iron, and plans to add oral minoxidil and restart derma rolling.

      community Hormonal panel after 1 year of treatment - DHT levels doubled!!

      in Finasteride/Dutasteride  8 upvotes 2 years ago
      A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.
      One-sided diffuse thinning - what should I do?

      community One-sided diffuse thinning - what should I do?

      in General  101 upvotes 4 months ago
      The user is experiencing one-sided diffuse thinning and has been using finasteride and liquid minoxidil for 4-5 years with minimal results. They are considering whether to save for a hair transplant or address scalp sensitivity and irritation first.

      community 8 months progress on fin + min

      in Progress Pictures  150 upvotes 2 years ago
      The user "Dame2Miami" shared their 8-month progress using finasteride and minoxidil for hair loss. Other users commented on their impressive gains and expressed support.

      community 23M on 0.25mg Finasteride 40 Days: Temporary Watery Semen?

      in General  50 upvotes 8 months ago
      A 23-year-old male taking 0.25 mg finasteride for 40 days noticed reduced hair shedding and improved hair texture but experienced watery semen, which might be temporary. Overejaculation and finasteride can cause this, and it usually resolves, but consulting a healthcare provider is advised if it persists.

      community Finally. Some tangible results. 9mos difference.

      in Progress Pictures  188 upvotes 4 months ago
      The user experienced significant hair improvement over nine months using a routine of oral finasteride, mixed topical and oral minoxidil, microneedling, and Head & Shoulders shampoo. The user attributes the progress to oral minoxidil and reduced stress during paternity leave.

      community Anyone else realize how many younger guys are balding?

      in Chat  262 upvotes 1 year ago
      Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

      community Debunking Androgenetic Theory (Hair Transplants)

      in Research/Science  25 upvotes 2 years ago
      The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

      community Hair loss as a hijabi in the middle east

      in Female  39 upvotes 4 years ago
      A woman experiencing hair loss, exacerbated by wearing a hijab, is seeking advice for her upcoming wedding. She has tried various treatments, including minoxidil, finasteride, and stem cell therapy, and is considering using hair fibers and extensions to cover her scalp.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Blood work after 4 month topical fin/min

      in Update  6 upvotes 1 year ago
      After 4 months of using topical finasteride and minoxidil, blood tests showed increased E2, Test, and Prolactine levels. The user is concerned about potential side effects like gyno and is seeking advice on managing these values.

      community Dutasteride just FEELS better than finasteride

      in Finasteride/Dutasteride  172 upvotes 1 year ago
      Dutasteride is favored over finasteride by some for better hair loss reversal, improved skin, and fewer side effects, though individual responses vary. It may also help with dandruff and eczema but has a slightly higher risk of gynecomastia.

      community Finasteride Watery Semen

      in Finasteride/Dutasteride  2 upvotes 5 years ago
      A user noticed watery semen and decreased volume after a week of using finasteride and asked if taking Zinc, pygeum, and lecithin supplements would affect finasteride's effectiveness. The conversation is about the side effects of finasteride and potential supplements to counteract them.

      community Testosterone, gray hair, low vitamin D, and switching to oral Minoxidil

      in Treatment  4 upvotes 5 years ago
      A woman experiencing hair loss due to high testosterone and low vitamin D is using treatments like Dutasteride, Rogaine, zinc, ketoconazole shampoo, dermastamp, iRestore, multivitamins, scalp massager, and vitamin D. She plans to switch to oral Minoxidil under medical supervision.

      community Bicalutamide vs Finasteride for female AGA plus TE

      in Female  3 upvotes 1 month ago
      OP is considering Bicalutamide for female AGA and TE but is concerned about its side effects and effectiveness compared to Finasteride. OP is also using Minoxidil and Spironolactone but is experiencing significant shedding and is unsure if it's androgen-driven or due to Minoxidil changes.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  13 upvotes 2 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Can HMI-115 reverse miniaturization?

      in Research/Science  12 upvotes 3 years ago
      HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

      community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry

      in Transgender  137 upvotes 4 years ago
      Hair loss discussion mentions using estrogen mixed with growth stimulants like oral minoxidil for scalp hair growth. Idea proposed for an artificial SARM-estrogen that only affects hair without body side effects.