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      community Pre-mixed RU58841 in the KB solution vs PG solution?

      in Treatment  4 upvotes 4 years ago
      Choosing between KB and PG solutions for applying RU58841, considering factors like scalp oiliness and absorption. Some users prefer KB for being gentler, while others use PG and recommend washing hair before application for better results.

      community What the hell happened to Breezula?

      in Research/Science  14 upvotes 10 months ago
      Breezula (clascoterone) Phase 3 hair loss trial results are delayed, with no official updates yet. The acne version is approved, but hair loss results are still pending.

      community Is Pyri worth it at the moment?

      in Chat  26 upvotes 2 years ago
      The conversation is about the effectiveness and safety of a hair loss treatment called Pyri, with users discussing its availability and comparing it to other treatments like RU58841, fluridil, and alfatradiol. Some users are waiting for FDA approval before using Pyri, while others share their positive experiences with RU58841 and suggest additional treatments with minimal side effects.

      community Does anyone use Fluridil as their anti-androgen of choice?

      in Chat  5 upvotes 2 years ago
      Fluridil, a non-steroidal anti-androgen approved for alopecia in parts of Europe, is noted for its low side effects but is not commonly discussed. The user is inquiring if anyone prefers it over other anti-androgens like Spiro or RU58841.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 1 year ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community PP405 is out for sale on everychem.

      in Product  98 upvotes 10 months ago
      PP405 is suspected to be a scam, with users doubting its legitimacy and effectiveness. Many recommend using proven treatments like finasteride and minoxidil.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community The Breezula 539% headline is doing a lot of heavy lifting right now.

      in Research/Science  14 upvotes 1 month ago
      Breezula shows promising results for hair loss, with one trial showing a 539% improvement and another 168%, but lacks combination data with treatments like minoxidil or dutasteride. Its mechanism differs from finasteride, potentially offering fewer side effects by blocking receptors locally at the follicle.

      community PP405 - hair stem cell stimulation

      in Research/Science  53 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community Thinking about using PP405 and RU58841

      in Research/Science  1 upvotes 5 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community I finally coninced my trichologist to give me finasteride

      in Treatment  2 upvotes 1 year ago
      The user convinced their trichologist to prescribe topical finasteride after using topical estradiol and progesterone for hair maintenance. They also discussed the potential impact of "nofap" on hair loss, noting that abstaining for about four months seemed to reduce shedding.

      community Chances GT20029 releases by 2028?

      in Technology  7 upvotes 3 years ago
      The conversation is about hair loss treatments, specifically the anticipation for the release of a new treatment, GT20029, by 2028. Users are discussing their experiences with current treatments like finasteride and dutasteride, and the potential of future treatments, including FAK inhibitors and verteporfin trials.

      community Why aren’t hair fibers popular?

      in Product  22 upvotes 2 years ago
      Hair fibers are discussed as a temporary solution for hair loss, with users noting they work well if applied correctly but can be messy and time-consuming. Some users also use finasteride for long-term treatment.

      community Minxodil collegen synthesis decrease?

      in Minoxidil  3 upvotes 1 year ago
      Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.

      community For everyone buying 2-deoxy-d-ribose (2ddr)

      in Research/Science  12 upvotes 1 year ago
      The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.

      community Pyrilutamide - your experience?

      in Product  12 upvotes 3 years ago
      The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  326 upvotes 11 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community Anybody used Fluridil ? Is my last hope.

      in Finasteride/Dutasteride  4 upvotes 3 years ago
      The conversation is about alternatives to finasteride for hair loss, with suggestions including fluridil, oral minoxidil, alfatradiol, and cb-03-01. Concerns about finasteride's side effects, including potential breast cancer risk, are also discussed.

      community When do you think Breezula will be released to the public?

      in Chat  32 upvotes 4 years ago
      The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.

      community Verteporfin mixing solute for transplants

      in Treatment  12 upvotes 2 years ago
      Doctors are testing verteporfin topically for healing and potential regeneration after transplants. The user is asking how it is formulated for topical use, such as if it's mixed with a carrier gel.