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      community 6 years fighting the Norwood reaper

      in Is this regrowth?  45 upvotes 11 months ago
      The user has been managing hair loss with microneedling, Nutrafol, topical finasteride/minoxidil foam, LLLT, and Nizoral, and plans to add oral minoxidil. They are seeing improvement and are cautious about using oral finasteride due to past gynecomastia concerns.

      community Seen Alfatradiol mentioned on here a few times recently and found this study - in case anybody is interested. Translated from German.

      in Treatment  4 upvotes 4 years ago
      Alfatradiol (0.025%) is an effective and safe treatment for androgenetic alopecia in both men and women, increasing anagen hair rates with minimal side effects. Users discuss its cost-effectiveness and ease of use compared to other treatments like finasteride and RU58841, with some combining it with stemoxydine and Minoxidil.

      community found out im more responsive to dutastetide than finasteride

      in Finasteride/Dutasteride  20 upvotes 3 years ago
      The user switched from finasteride to dutasteride for hair loss and saw significant improvement in under two months. They also microneedle, take supplements including collagen and vitamin D3, use ketoconazole shampoo, and noticed accidental hair regrowth with retinol application on their face.

      community cosmeRNA finally now it's pyrilutamide turn

      in Chat  48 upvotes 3 years ago
      Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

      community Who said GT20029 would be applied only few times per month?

      in Research/Science  11 upvotes 3 years ago
      The conversation discusses the safety and effectiveness of a hair loss drug, GT20029, and the possibility of infrequent application, with users hoping for once-daily use and speculating on the drug's duration of effect on the scalp. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community The mechanism of androgenic alopecia

      in Research/Science  34 upvotes 8 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community Alfatradiol 1% study rebuttal.

      in Research/Science  5 upvotes 2 years ago
      Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.

      community Finasteride with Low Ferritin and Copper

      in Finasteride/Dutasteride  3 upvotes 9 months ago
      The user is experiencing hair loss and is using finasteride while addressing low ferritin and copper levels. They are concerned about continued hair shedding and are advised to correct vitamin deficiencies and wait for finasteride results after 12 months.

      community 11 months on fin only. Regrowth + thickness

      in Progress Pictures  572 upvotes 2 years ago
      A user reported hair regrowth and increased thickness after 11 months using finasteride 1mg, taken 3-4 times a week, with noticeable improvement starting around the third or fourth month. No side effects were mentioned, and the user is considering reducing the dosage to find the minimum needed to maintain results.

      community Finasteride affects both 5a reductase and 5b reductase

       6 upvotes 6 years ago
      Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.

      community Fighting Fin!

      in Finasteride  10 upvotes 7 years ago
      Datwagg63 started taking finasteride for hair loss and supplements it with omega 3, vitamins, and a low-carb diet while lifting weights. InternationalBerry suggested adding minoxidil, as it's considered the second most effective treatment after finasteride.

      community Brothers in baldness any news on pyrilutamide

      in Chat  12 upvotes 3 years ago
      The conversation is about the potential effectiveness of a hair loss treatment called pyrilutamide. One person has been using it since September and reports positive results.

      community 22 years since the last major development

      in Technology  51 upvotes 5 years ago
      The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

      community Painkillers May Block Minoxidil

      in Research/Science  14 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community PYRILUTAMIDE VS RU58841 users which is superior

      in Update  27 upvotes 3 years ago
      Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

      community Is hair cloning and setipiprant coming in 2020?

      in Question  5 upvotes 9 years ago
      The conversation discusses potential hair loss treatments, including hair cloning, setipiprant, and topical finasteride, questioning their availability and effectiveness as permanent cures. The user is inquiring about the release dates and efficacy of these treatments.

      community Does caffeine inhibit 5-α-reductase?

      in Treatment  4 upvotes 6 years ago
      Caffeine may promote hair growth and potentially inhibit 5-α-reductase activity in hair follicles, but its effectiveness and systemic impact remain unclear. Users discuss using topical caffeine solutions, with some experiencing no side effects compared to finasteride.