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      community Targeting multiple AGA mechanisms with commonly available substances

       4 upvotes 7 years ago
      The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.

      community Does pyri/kx826 degrade in exposure to bathroom light?

      in Treatment  5 upvotes 1 year ago
      The conversation discusses concerns about RU58841 degrading when exposed to light and transferring pyri to a dark glass bottle to prevent this. The user keeps the pyri out for only two minutes before storing it in a dark place.

      community The Big Fat Layer / Remedies: Cetirizine

      in Treatment  9 upvotes 5 years ago
      Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.

      community What to take from the Actifolic?

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The user is considering starting Minoxidil and is looking for a topical solution to combine with it. They are confused about which product to prioritize among options like RU58841, Pyrilutamide, FinaTopic, and DutaTopic.

      community Verteporfin to deminiaturize follicles

      in Research/Science  9 upvotes 3 years ago
      User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.

      community Nearly a year of fin and no progress

      in Update  37 upvotes 1 year ago
      The user has been using finasteride, minoxidil, and other treatments for nearly a year without progress in hair regrowth, feeling frustrated and depressed. Suggestions include trying dutasteride, considering a scalp biopsy, and acknowledging that stopping hair loss might be the only achievable outcome.

      community Rant: How to stop hating myself for delaying treatment?

      in Chat  11 upvotes 9 months ago
      The conversation discusses regret over delaying hair loss treatment, specifically with finasteride, and the emotional impact of hair loss. The user eventually stabilized their hair using oral finasteride after trying other treatments like topical finasteride, Fluridil, and Alfatradiol, and is considering future options like a hair transplant.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  2 upvotes 3 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community Why nobody uses 0.25% (2.5mg/ml)?

      in Treatment  66 upvotes 2 years ago
      The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

      community Topical dutasteride significantly outperforms oral finasteride

      in Research/Science  65 upvotes 6 months ago
      Topical dutasteride 0.05% is reported to outperform oral finasteride with minimal side effects, but concerns about study bias exist due to company funding. Some users report mixed results with topical dutasteride, noting issues with skin penetration and systemic absorption.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      in Research/Science 1 month ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community Best way to apply tretinoin?

      in Minoxidil  13 upvotes 5 years ago
      The conversation is about using tretinoin to enhance minoxidil's effectiveness for hair loss, discussing whether to mix tretinoin with minoxidil or apply it separately, and considering the concentration of tretinoin to use.

      community M20 on Fin+Min for 1 Year – Crown Still Thin, Should I Add Dut/Oral Min?

      in Progress Pictures  26 upvotes 6 months ago
      A 20-year-old has been using finasteride and topical minoxidil for a year but is considering adding oral minoxidil, dutasteride, and biotin due to unsatisfactory results. Opinions vary, with some suggesting patience and others recommending different treatments, but caution is advised against using multiple oral drugs due to potential side effects.

      community 20 months in… and i hate where i am

      in Progress Pictures  54 upvotes 3 months ago
      The user has been using finasteride and topical minoxidil for hair loss since April 2024 but feels their condition has worsened. They are considering switching to oral minoxidil or dutasteride for better results.

      community Minoxidil + tretinoin usage frequency

      in Minoxidil  1 upvotes 1 year ago
      A user is seeking advice on how often to use a minoxidil solution with 0.025% tretinoin, considering using it every other evening instead of regular minoxidil twice a day. They are asking for experiences and opinions on this usage frequency.

      community 10 months of topical fin/min progress

      in Progress Pictures  31 upvotes 11 months ago
      The user shared progress pictures after 10 months of using topical finasteride and minoxidil, along with dermarolling and specific shampoos. Some users suggested switching to oral treatments for better results, while others noted visible improvements in hair thickness and regrowth.

      community May 2022 - September 2022. 4 month results on 2x daily minoxidil, finasteride, nizoral 2x weekly. Taken in the same office to try and keep lighting consistent.

      in Progress Pictures  637 upvotes 3 years ago
      Vat-R-U-Talkin-About: I'm not sure that wearing a hat would have an effect on either Minoxidil or Finasteride. It may be worth experimenting with not wearing one for a few weeks to see if it makes any difference. This conversation is about a user's progress pictures four months into taking minoxidil, finasteride, and nizoral twice weekly to treat hair loss; others shared their experiences and offered advice on how to improve the treatment.

      community (30M) 3 years Fin and 10 months min

      in Progress Pictures  307 upvotes 1 year ago
      A user shared their progress using 1.25g finasteride daily for 3 years and 5g oral minoxidil for 10 months, reporting positive results. They seek advice on further improving their hairline, with no significant side effects mentioned.

      community I've finally found the cure

      in Satire  204 upvotes 5 years ago
      A regimen for hair loss, which includes using Nizoral shampoo twice daily, Minoxidil foam from the can, 5mg of Propecia crushed and snorted on weekends, and dermastamping directly to the head of the penis. Replies discuss potential sides and other treatments, as well as the idea that confidence is more attractive than hair.

      community Help On Topical Finasteride 0.3%

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      A user is seeking advice on a new topical hair loss treatment containing Minoxidil 3%, Finasteride 0.3%, Progesterone 1%, Hydrocortisone butyrate 0.1%, and Ketoconazole 0.5%. They are concerned about the systemic absorption of Finasteride and plan to do blood tests and a spermiogram before starting.

      community 4 years (2 years fina, soon 2 years Dut) and topical / oral min

      in Progress Pictures  3 upvotes 2 weeks ago
      The user started hair loss treatment at 19 with oral finasteride and topical minoxidil, later switching to oral Dutasteride and oral minoxidil. Despite ongoing treatments, including microneedling and topical applications, hair loss, particularly at the hairline, continues to progress.