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      community Progressive insomnia (treatment-resistant) due to Finasteride

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  5 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community 85 days Topical Min-Fin progress

      in Is this regrowth?  10 upvotes 6 months ago
      The user has been using a treatment of 0.1% topical finasteride, 5% minoxidil, dermastamping, and vitamin D3 supplements for 85 days and is seeing good progress. Other users note the effectiveness of topical finasteride despite it being less potent.

      community Low topical fin + 0.5% pyrilutamide

      in Research/Science  2 upvotes 1 month ago
      Using a combination of low-dose topical finasteride (0.025%) and 0.5% pyrilutamide for hair loss, with a focus on minimizing side effects. The user seeks experiences and results from others who have tried this combination.

      community 8 months - 2,5mg OM / Topical MinFin

      in Progress Pictures  176 upvotes 2 years ago
      User shares 8-month hair growth progress using 2.5mg oral minoxidil and 2ml topical minoxidil/finasteride mix. Others comment on noticeable improvement and discuss user's journey and treatment details.

      community 8 months Fin and Min. Now on stronger regiment

      in Progress Pictures  7 upvotes 1 year ago
      The user shared progress pictures after 10 months of hair loss treatment, initially using 1mg Finasteride and 5mg Minoxidil, then switching to 2.5mg Minoxidil, topical Minoxidil, and RU58841. Recently, they added 0.5mg Dutasteride to their regimen.

      community Fresh off the press: Dutasteride may cause chronic infertility

      in Research/Science  643 upvotes 1 year ago
      Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

      community 4 month Min+Fin progress (topical)

      in Progress Pictures  124 upvotes 1 year ago
      A user shared their 4-month progress using a topical solution with 5% minoxidil and 0.1% finasteride, applied twice daily. They reported good results despite occasional missed applications.

      community Verteporfin to deminiaturize follicles

      in Research/Science  7 upvotes 3 years ago
      User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.

      community How much caffeine to add to home solution

      in Research/Science  5 upvotes 2 years ago
      A user is creating a home topical solution for hair loss using zinc, essential oils, and caffeine, aiming for a 0.001% caffeine concentration. They also use topical finasteride and are considering other treatments like low-level laser therapy, while discussing the effectiveness of various hair loss treatments with others.

      community How long is RU58841 active after application

      in Research/Science  1 upvotes 1 year ago
      RU58841 remains active for several hours after application, and it's suggested to wait a few hours before washing it off to maintain its effectiveness. There is a concern about potential transfer to others if they touch the hair shortly after application.

      community Why was fluridil abandoned and never made past phase 2?

      in Chat  4 upvotes 4 years ago
      Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

      community Switch to Dut??

      in Finasteride/Dutasteride  11 upvotes 6 years ago
      Considering a switch from finasteride to dutasteride for hair loss treatment, and the use of minoxidil as a last resort due to its effects on hair texture.

      community Creating Your Own Topicals: A Guide

      in Research/Science  69 upvotes 3 years ago
      Creating a carrier solution for topical hair loss treatments using ethanol, propylene glycol or glycerin, and instructions on creating topical finasteride. Different recipes are provided with varying ratios of alcohol to humectant.

      community My final attempt at creatine with fin

      in Product  41 upvotes 8 months ago
      Creatine may cause hair shedding and texture changes, with mixed user experiences. Combining creatine with finasteride doesn't always prevent these effects, possibly due to individual DHT sensitivity.

      community Hairline stable but diffuse thinning with topical fin+min

      in Finasteride  237 upvotes 1 month ago
      The user experienced stable hairline but diffuse thinning after switching from oral finasteride to a topical solution of minoxidil and finasteride. They are concerned about the effectiveness of the topical treatment and are considering other options due to a recent decline in hair density.

      community Recommend stemoxydine as an adjunct therapy

      in Treatment  5 upvotes 2 years ago
      The user has been using finasteride, minoxidil, retinoid, and occasional microneedling for hair loss with good results. They recently added stemoxydine, which improved their hair further, and suggest trying it, especially in the EU where it's easily available.

      community Worth it to add topical fin to oral fin?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user is taking 1mg finasteride daily and RU58841 5% but still experiencing hair loss. They are considering adding topical finasteride or switching to dutasteride, and are not planning to use minoxidil until hair loss stabilizes.