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      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 7 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community I found the solution for the Minox dandruff problem

      in Minoxidil  8 upvotes 5 years ago
      A user found a solution for Minoxidil-induced dandruff by using a custom NRF 11.121 mixture from a local pharmacy, which includes ingredients like Isopropyl palmitate and Cremophor RH 40. This formulation prevents dryness and allows better penetration when using hair shaders.

      community Does anyone else have experience with Patented Growth Factors (PGF) Treatments / experiences with depression on Fin/Min/Dut?

      in Treatment  1 upvotes 1 year ago
      The user is exploring hair loss treatments, including Patented Growth Factors (PGF) and a serum with Copper Peptide, Ceramides, Amino Acids, and Caffeine, while expressing concerns about the cost and effectiveness of PGF. They are also considering starting finasteride due to doubts about PGF's long-term viability and are seeking experiences from others who have used these treatments alongside antidepressants.

      community Liquid Min drinkers be like : “Why is this happening?!”

      in Satire  537 upvotes 1 year ago
      People are humorously discussing unconventional and satirical uses of minoxidil, such as drinking it or injecting it, and the potential absurd consequences. The conversation also touches on the ineffectiveness and risks of these methods compared to proper topical application with microneedling.

      community Brotzu lotion update

      in Update  89 upvotes 8 years ago
      A new hair loss lotion by Dr. Brotzu, expected to regrow up to 5 years of lost hair, is set to be released by Fidia Farmaceutici. It claims to work like minoxidil and finasteride without side effects, but skepticism exists due to its classification as a cosmetic product.

      community Collagen peptides(powder) i highly recommend

      in Product  8 upvotes 1 year ago
      Collagen peptides are recommended for hair and skin benefits, with users noting improvements in hair and skin health. However, evidence on their effectiveness for hair growth is inconclusive.

      community How to make Azelaic acid solution from powder?

      in Research/Science  1 upvotes 5 months ago
      Azelaic acid is discussed for its anti-inflammatory and anti-fungal properties, which can improve scalp health and potentially boost hair growth. It is suggested for topical use, especially alongside minoxidil.

      community Has anyone heard of “Hair bloom” hair filler?

      in Treatment  5 upvotes 1 year ago
      The conversation discusses "Hair bloom" hair filler, which contains biotin, collagen, and various peptides, as a potential alternative to PRP or mesotherapy for hair loss. Opinions vary, with some suggesting it may be a cash grab or ineffective, while others believe it could complement topical minoxidil for early hair loss.

      community Pre styler thickening clay recommendation

      in Product  2 upvotes 7 months ago
      The user recommends a thickening clay as a great pre-styling product for hair volume and texture, despite its poor hold. They also mention using finasteride and express skepticism about the effectiveness of a shampoo containing saw palmetto and caffeine.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community I just made 60x of 5mg minoxidil sugar cubes

      in Minoxidil  1338 upvotes 1 year ago
      A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

      community Topical Fin +Min dose correction

      in Finasteride/Dutasteride 2 years ago
      A user experiencing side effects from a 5% minoxidil and 0.1% finasteride topical solution for hair loss reduced their dosage due to numbness and pain in the lower body and is seeking advice on dosage and alternatives like redensyl. They are concerned about the side effects of both medications and are considering adjusting the dose or switching treatments.

      community Serum containing minoxidil and bimatoprost analogs

      in Product 1 year ago
      A user discusses using a serum called Dallixa, containing minoxidil-like and bimatoprost-like compounds, for hair loss and greying. The user's dermatologist advised against finasteride and suggested the serum might improve hair pigmentation.

      community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?

      in Treatment  5 upvotes 6 months ago
      The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

      community lost all my gains switching from liquid to foam

       5 upvotes 7 years ago
      Switching from liquid to foam minoxidil led to hair loss for OP, possibly due to a second shedding cycle. OP experienced allergic reactions to propylene glycol in the liquid form, causing dandruff and itchiness, which improved after switching to foam.

      community A small tip for diffuse thinners

      in Product  7 upvotes 4 years ago
      A user with diffuse thinning shares a tip for improving hair appearance by using a shea butter and coconut oil serum from Trader Joe's at night. They are on finasteride and considering adding minoxidil for better results.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 8 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Homemade topical fin vs. pharmacy made topical fin

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      A user is considering making their own topical finasteride from crushed Propecia tablets and asks if there would be any difference compared to pharmacy-made versions or products like Essegen-F. They note that making drugs at home is generally not recommended.

      community PP405 (Everychem 3HP) users - assemble and share your updates!!

      in Chat  44 upvotes 2 months ago
      Users discussed experiences with Everychem's solution similar to PP405 for hair loss, noting some positive results like increased hair thickness and new growth. There was skepticism about the product's legitimacy and safety, with some users reporting early signs of effectiveness and others expressing concerns about the lack of evidence and safety profiles.