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      community Update: going nuclear! (Switch to dut)

      in Update  13 upvotes 2 months ago
      The user had a hair transplant in March 2025 and has been using finasteride since 2023, which halted hair loss but didn't fully restore density. They plan to use dutasteride twice weekly, finasteride five times a week, and saw palmetto to improve hair thickness.

      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 8 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Pyrilutamide almost for 9 months

      in Progress Pictures  62 upvotes 2 years ago
      The user has been using pyrilutamide, topical finasteride, and 15% minoxidil for hair growth for almost 4 years. Despite mixed responses from others, the user reports seeing progress, especially with the addition of pyrilutamide, and plans to continue the regimen.

      community [29 M] 7 month pyrilutamide update.

      in Progress Pictures  126 upvotes 1 year ago
      A 29-year-old male experienced hair regrowth using minoxidil 5% foam and KX826 after stopping finasteride due to side effects. He applies both treatments once daily and reports no side effects from the current regimen.

      community To everyone who cant use FIN and doesnt want to use RU

      in Treatment  33 upvotes 1 year ago
      A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.

      community RU55481

       4 upvotes 12 years ago
      The conversation discusses using RU58841, a research chemical, for hair loss treatment. The user plans to use it due to side effects from finasteride and minoxidil, despite skepticism about its effectiveness and lack of FDA approval.

      community Topilutamide (fluridil) raw active?

      in Research/Science  7 upvotes 5 years ago
      Topilutamide is a potential hair loss treatment between Clascoterone and RU58841. Users discuss finding Topilutamide powder and its possible benefits for those who can't afford or tolerate other treatments.

      community GT20029 and PP405 the new fin and min that we been waiting for ?

      in Chat  36 upvotes 11 months ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

      community Using RU58841 instead of finasteride.

      in Treatment  2 upvotes 4 months ago
      The user stopped using finasteride due to side effects and switched to RU58841, which seems to be working for hair regrowth. They are considering RU58841 and minoxidil as long-term treatments, while others discuss the safety and effectiveness of these options.

      community All Drugs in Clinical Trials in 2023

      in Research/Science  71 upvotes 3 years ago
      12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

      community Does anyone take bicalutamide for fphl? If so which dose

      in Female  4 upvotes 3 years ago
      The conversation is about a female seeking advice on using bicalutamide for female pattern hair loss (FPHL) and considering switching from pumpkin seed oil pills to a stronger treatment. She is looking for dosage information to discuss with her dermatologist.

      community My endless RU58841 cycle [experience thread)

      in Update  10 upvotes 1 year ago
      The user experienced hair loss and itching after stopping RU58841 and resumed it to stop these symptoms. They also use Dutasteride and question which treatment is effective.

      community Anyone else just waiting until the real pyrilutamide and then GT20029?

      in Chat  5 upvotes 2 years ago
      The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

      community Just introduced RU wish me luck!! (+ whats working for me) NO MIN!

      in Treatment  5 upvotes 2 years ago
      The user is using finasteride, RU58841, and various natural supplements and treatments like seamoss, fish oil, and black rice water spray to combat hair loss, avoiding minoxidil due to dependency concerns. They report thicker hair and regained confidence, while discussing the potential risks and benefits of RU58841 with others.

      community Progress with 6 Years fin and a FUT (2017 vs 2023)

      in Is this regrowth?  210 upvotes 2 years ago
      The post discusses a user's six-year progress with finasteride and a Follicular Unit Transplant (FUT) for hair loss. The user shared before and after photos in reverse order, leading to confusion, but overall, the community responded positively to the user's hair regrowth.

      community 6 months of finasteride and ghk-cu

      in Progress Pictures  18 upvotes 2 months ago
      The conversation is about hair loss treatment progress using finasteride and GHK-CU over six months. Users discuss application methods and share experiences with GHK-CU and AHK.

      community Chinese Research Chemicals You Suggest

      in Research/Science  3 upvotes 10 months ago
      The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.

      community Prediction: Scube3 is never coming out

      in Research/Science  6 upvotes 2 years ago
      Scube3, a potential hair loss treatment, is unlikely to be released because it was given to a startup company, Amplifica, which may go bankrupt and fail to bring the treatment to market. Amplifica is prioritizing other treatments over Scube3, which could lead to financial loss and the end of Scube3's development.

      community My Near-Nuclear Stack is Saving me; Hyperresponder?

      in Progress Pictures 1 year ago
      An 18-year-old is using a high-dose hair loss treatment regimen including finasteride, minoxidil, dutasteride, and plans to add RU58841 and bimatoprost, despite warnings from others about the risks. The user is determined to reverse hair loss but acknowledges the potential dangers and does not recommend others follow their approach.

      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  11 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community Kintor’s GT20029 Phase 1 success

      in Update  74 upvotes 3 years ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community CB-03-01 / Breezula Personal Results

      in Treatment  17 upvotes 4 months ago
      The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

      community 3 Month Results with Nuclear Stack - 42M

      in Progress Pictures  114 upvotes 1 year ago
      A user shared 3-month hair regrowth results using a combination of oral Dutasteride, daily Minoxidil, RU58841, micro-needling, Keto shampoo, scalp massages, and supplements. Positive progress was noted, and encouragement to continue was given.