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RU58841 showed promise for treating androgenic alopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.

User shared progress pictures after 2 months of using 1mg finasteride for hair loss. They are seeking feedback on any improvement.

A user's 3-month progress with a combination of finasteride, minoxidil and dermarolling for hair loss; other users shared their experiences and advice.

The conversation is about a 40-year-old trying a homemade topical hair loss treatment combining finasteride and minoxidil, and considering microneedling after previous side effects from oral finasteride. They plan to provide updates on the results and any side effects.

The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

User shared 18-month progress using 1 mg finasteride daily and varying doses of oral minoxidil. Minoxidil caused side effects managed with taurine, dandelion root, sauna, and collagen.

The user has been using 1 mg finasteride daily for 3 months, with recent additions of 2.5 mg oral minoxidil and microneedling, and is seeing some hair regrowth. They are seeking opinions on their progress and discussing treatment options with others.

The user started using finasteride and minoxidil in October 2025 and noticed hair growth and thickening after three months, despite initial concerns about side effects. They are hopeful for continued progress and grateful for the support from the forum community.

User shared progress on crown regrowth using Minoxidil Foam, oral Minoxidil 2.5mg daily, and Finasteride 1mg daily. They experienced initial headaches with oral Minoxidil, had a hair transplant, and are seeing regrowth but with thin hairs.

Fluridil's effectiveness and safety in treating hair loss are discussed, with higher concentrations showing potential success. Comparisons are made to other treatments like RU58841, Pyri, CB-03-01, and topical spironalactone.

A 33-year-old man has seen no improvement in hair loss after using topical Minoxidil and Finasteride for 5-6 months, despite also derma rolling and using keto shampoo. He experienced severe side effects from oral Finasteride and is seeking advice on alternative treatments.

The post is about a user's one-year progress in treating hair loss with finasteride and minoxidil. The conclusion is that the user experienced gradual improvement each month, with significant results after one year.

A user shared their one-year progress using finasteride 1mg three times a week, starting at age 25, with noticeable regrowth after three months and no side effects. Other users discussed their experiences with finasteride, minoxidil, microneedling, and dutasteride, noting varying results and side effects.

Applying minoxidil in the morning and topical finasteride at night. Mixing finasteride with liquid minoxidil is planned after finishing foam bottles.

The user experienced side effects from finasteride and is considering switching to dutasteride, while also using pyrilutamide to protect hair follicles. They are seeking advice on whether to add RU58841 to their regimen.

The user experienced significant hair regrowth in the temple area after using 1mg finasteride daily for over a year, with no side effects. The user did not use minoxidil or microneedling and started experiencing hair loss at age 16.

The user noticed potential hair growth after 13 days of using RU58841, alongside a regimen of oral minoxidil, finasteride, and topical minoxidil. Others think it's too soon to see results, and some are surprised by the high dosage of oral minoxidil.

Significant hair regrowth was achieved using 5% Minoxidil twice daily and weekly microneedling with a 0.8 mm dermaroller over five months. Finasteride was not used due to concerns about side effects and availability in France.

Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss. The user is considering using these alongside Pyrilutamide 0.9%.

A 23-year-old is using a topical 5% finasteride/minoxidil spray, microneedling, and taking biotin and vitamin D for hair regrowth, noticing slight improvement but still experiencing thinning. They are considering switching to oral finasteride but are concerned about potential side effects.

A 27-year-old man shared his 3-month progress using finasteride and minoxidil for hair loss, showing significant improvement and increased confidence. He expressed gratitude to the community for their support and inspiration.

User seeks availability of Breezula and its delayed trials. Asks for success with similar topical antiandrogens like fluridil.

A user experienced unexpected hormone test results after 7 months on 1mg daily finasteride, noting a decrease in estradiol despite expectations of an increase. Other users suggested that hormone responses can vary and that finasteride might still be effective if DHT levels are within range, while also mentioning factors like circadian rhythm and stress that could impact results.

PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

A 28-year-old male reports progress in hair regrowth using 5mg Minoxidil and 0.5mg Dutasteride, noting improvement in the crown area. Another user shares similar positive results since starting treatment in January.

Mixing Pyrilutamide powder with Minoxidil solution is being considered. The Minoxidil solution contains Minoxidil 5%, Azelaic acid 5%, ABN complex 0.8%, Retinol 0.025%, Caffeine 0.001%, and a delivery vehicle.

User shares 1-year progress using 1mg Finasteride and 5% Minoxidil daily. Others praise results, discuss when improvements appeared, and mention shedding phase.

RU58841 caused chest tightness, throat irritation, and headaches, leading the user to stop its use. The user plans to restart with a lower dose if symptoms fully disappear but remains cautious due to anxiety and side effects.

Hair loss discussion mentions HMI-115 efficacy in 3 months after Phase II study. Users discuss treatment effectiveness and mention massive regrowth in previously bald areas.

Availability of topical anti-androgens, especially RU58841, in Australia. Issues with customs seizures and lack of credible local sources.