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Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

The conversation discusses various hair growth treatments, including topical and oral minoxidil, microneedling, LLLT, PRP, exosomes, latanoprost, copper peptides, and upcoming treatments like PP405 and Vdphl01. It also covers managing side effects of minoxidil, such as dry scalp, and mentions the use of dutasteride and finasteride for hair loss.

Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

A 20-year-old shared their experience of reversing hair loss without using minoxidil or finasteride, instead relying on supplements like biotin, collagen, fish oil, saw palmetto, and various vitamins. They emphasized the importance of a balanced supplement schedule and noted improvements in hair health without experiencing additional shedding.

The user has been using oral finasteride and topical minoxidil for three years, seeing some regrowth initially but mostly maintenance afterward. Suggestions for further improvement include trying dutasteride, RU58841, or a hair transplant.

A user shared a 7-month update on hair regrowth using finasteride daily and minoxidil once a day, noting improvement in hair health. Others suggested adding micro-needling, ketoconazole shampoo, and considering a hair transplant for better results.

A new plant-based serum is claimed to regrow hair in weeks, but users are skeptical about its effectiveness and the reliability of the study. Ingredients like Centella Asiatica and IGF-1 are mentioned, but many doubt the serum's superiority over existing treatments like Minoxidil and finasteride.

The user shared their 5-year progress using finasteride and topical minoxidil for hair growth, noting initial success but recent thinning and side effects. They plan to switch to dutasteride and oral minoxidil, addressing low iron levels and monitoring potential side effects.

User had minor hair transplant in 2020, used Fin since 2008, Min since 2014, and added microneedling in 2022. Routine was irregular with no severe effects.

PP405 is a promising new treatment for hair loss that activates dormant stem cells in hair follicles, potentially bypassing the effects of DHT. It is currently in phase 2 trials and could be available between 2027 and 2030, but it is not considered a definitive cure.

The user shared progress pictures showing hair regrowth over 7 months using topical Minoxidil, topical Finasteride, and multivitamins with biotin, noting more regrowth at 3 months than at 7 months. They suspect a shedding phase and are considering the impact of not continuing microneedling.

User shared progress with 3 months on topical minoxidil, 1 year on finasteride, and micro-needling every couple of weeks. Others praised hair growth and shared reactions.

A 48-year-old man has been using finasteride at 1mg three times a week for two years, seeing some hair regrowth but noting lighting affects appearance. He is considering adding minoxidil but is concerned about shedding.

The user is experiencing hair regrowth and increased hair thickness after using supplements like biotin, zinc, selenium, and a complex with various natural ingredients, along with topical caffeine. They are considering using topical minoxidil and mesotherapy in the future.

A user used Minoxidil twice daily, 1 mg finasteride in the morning, and a dermaroller weekly for a year but is unhappy with the results and sperm quality. Others suggest continuing the regimen, noting hair maintenance and thickness, and considering additional treatments like dutasteride or a hair transplant.

The user has been using finasteride for 18 years to manage hair loss and is considering starting minoxidil and possibly a hair transplant. Despite some regrowth, they are exploring additional treatments like dutasteride and oral minoxidil due to continued hair thinning.

The conversation discusses the effectiveness of New Nordic Hair Gro tablets for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

After a hair transplant, the user noticed unexpected new hair growth without using medications or vitamins. Many advised starting treatments like minoxidil and finasteride to maintain the results and prevent future hair loss.

User has been using 1.25 mg finasteride and 2.5 mg minoxidil daily for 5 months, along with 5000 mcg biotin for 1.5 months. They noticed peach fuzz growth around month 4 and are seeking confirmation if this indicates hair regrowth.

The user reports a stable receding hairline with new hair growth after using 5% minoxidil, 1mg oral finasteride, D-Biotin daily, derma rolling twice a week, and three PRP sessions per month. They plan to update their progress in four months.

The conversation is about a user trying hair fibers to cover hair loss while waiting for Rogaine (Minoxidil) to work. Some suggest using Finasteride or other treatments for better results, while others criticize the appearance of the fibers.

The user reported hair regrowth after using 1 mg finasteride daily for 4 months, foam minoxidil twice daily for 6 months, and 5000 mcg biotin daily for 4 months. Commenters are impressed with the results and some are considering starting finasteride after seeing the progress.

The user has maintained hair with topical minoxidil (8%) and finasteride (0.01%) for 7.5 years, experiencing mild regrowth and no side effects. They also use rosemary oil, jojoba oil, and magnesium oil for hair care.

The user experienced significant hair thickening and temple hair growth after one year of using finasteride, minoxidil, and weekly dermarolling. They are considering asking their dermatologist about dutasteride.

New hair growth from minoxidil and finasteride is not reaching full length, possibly due to slow growth cycles. Users discuss dosing strategies for oral minoxidil to improve efficacy and minimize side effects, with advice against consuming topical minoxidil orally.

The user has been using finasteride, minoxidil, and microneedling consistently for one month to improve hair regrowth. They also use collagen peptides, pumpkin seed oil, vitamin D, biotin, nizoral shampoo, adenosine shampoo, caffeine topical, and rosemary oil as part of their routine.

The user started taking oral finasteride after four years on oral minoxidil due to thinning hair in the crown area. They experienced some initial side effects and shedding but are hopeful for regrowth, while continuing with minoxidil.

PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

A user shared their successful hair regrowth journey using finasteride, oral minoxidil, and oral dutasteride, expressing gratitude for the support received. The conversation includes congratulations and encouragement from others.

The conversation discusses "Hair bloom" hair filler, which contains biotin, collagen, and various peptides, as a potential alternative to PRP or mesotherapy for hair loss. Opinions vary, with some suggesting it may be a cash grab or ineffective, while others believe it could complement topical minoxidil for early hair loss.