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community P-1075: a BETTER version of Minoxidil

in Research/Science 9 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community The amazing fast pace of PP405.

in Chat 327 upvotes 10 months ago

PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

community Do you believe these studies are real or just fear mongering

in Finasteride/Dutasteride 157 upvotes 10 months ago

Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.

community How likely do you think it is for PP405 to come out?

in Research/Science 21 upvotes 10 months ago

PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

community Can Low Vitamin D and Ferritin Impact Pace of Minoxidil Regrowth ?

in Minoxidil 2 upvotes 10 months ago

Minoxidil regrowth may be slowed by low vitamin D and ferritin levels. The user is experiencing slow hair regrowth and is considering addressing these deficiencies.

community hairloss treatment, what to expect (bloodwork)

in Treatment 1 upvotes 10 months ago

The conversation discusses hair loss treatment options, focusing on finasteride and its potential effects on gynecomastia. The user is considering finasteride while managing hormone levels with supplements like boron, vitamin D, zinc, magnesium, and P5P, and is advised to consult an endocrinologist for further evaluation.

community Progress in miniaturization or time to go to a psychiatrist?

in General 139 upvotes 10 months ago

A 21-year-old is concerned about androgenic alopecia and has been using minoxidil for a year, noticing some stabilization in the hairline but fears using it on the whole scalp due to seborrheic dermatitis. Another person suggests considering a psychiatrist for stress management, using Nizoral shampoo, and possibly trying a small dose of finasteride.

community Microneedling versus Platelet-Rich Plasma

in Research/Science 9 upvotes 10 months ago

Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

community Does alfatradiol do anything to help? Is anyone actually using this?

in Product 4 upvotes 10 months ago

Alfatradiol is used as a mild treatment to slow or stabilize hair loss, often alongside finasteride and pumpkin seed oil. Users report reduced shedding and minimal side effects, but minoxidil is noted as more effective for regrowth.

community 2 % fucoidan significantly alleviated AGA symptoms, promoted hair growth, and increased hair density

in Research/Science 23 upvotes 10 months ago

2% fucoidan alleviated AGA symptoms, promoted hair growth, and increased hair density in mice. Fucoidan is considered safe for humans as a supplement and topical skincare product, with potential therapeutic effects against AGA.

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