TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
A 31-year-old uses Minoxidil, RU58841, Reviv Hair Serum, and Ketoconazole shampoo for hair loss but avoids finasteride. They plan to reintroduce red light therapy (LLLT) and Eucapil despite previous shedding concerns.
The user has been using topical Minoxidil and finasteride for 5 months without seeing regrowth, despite ideal blood test results. They are seeking advice on what to do next due to frustration with continued hair loss.
The user has been using finasteride and minoxidil for almost 2 years with maintenance but no significant regrowth. After adding tretinoin 2 weeks ago, they experienced increased shedding and are seeking advice on whether this is a positive sign.
The user has been experiencing hair loss since having COVID and has low vitamin D levels; they are seeing some improvement in their crown and hairline after starting vitamin D supplements. Commenters suggest the hair loss pattern is consistent with male pattern baldness (MPD) and varies by individual.
Minoxidil and finasteride can help regrow hair, especially in thinning areas, but restoring completely receded temples is challenging and may require a hair transplant. Some users report success with these treatments, particularly when combined with microneedling.
A user has been taking finasteride, using a derma-roller, LLLT, and argan oil, but experienced significant hair loss at the one-year mark. They are concerned if this is a normal shedding phase or something to worry about.
Hair loss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.
Three months into using Minoxidil, finasteride, dermarolling, tretinoin, and saw palmetto shampoo, the user is seeing baby hairs on their hairline and is hopeful they will thicken. Another user reports that their own baby hairs have been getting thicker and longer over time.
The user is experiencing intense hair shedding all over the scalp after applying pyrilutamide to the hairline and taking oral castor oil. They are also using topical finasteride and latanoprost, but are unsure which treatment is causing the shedding.