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      community Topical Pyrilutamide - Hormone Panel

      in Treatment  2 upvotes 2 years ago
      The user used 0.5 mL of 0.5 mg of Pyrilutamide for 60 days for hair loss, but didn't notice any hair growth. They shared their hormone panel results and are seeking advice on next steps.

      community 2.5mg to 5mg OM after 2 weeks too soon?

      in Minoxidil  2 upvotes 1 year ago
      A user started taking 2.5mg oral Minoxidil (OM) and 1mg Finasteride after using topical Finasteride, Minoxidil, and Tretinoin for 2.5 months. They are considering increasing the OM dose before an upcoming hair transplant to improve its success.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community 2 year fin/min progress (age 27-29)

      in Progress Pictures  302 upvotes 2 years ago
      A user's two-year progress using 1mg of oral finasteride daily and twice daily application of 5% minoxidil solution for hair loss. The user experienced temporary side effects but is pleased with the results, and another user warns about the importance of consistent use for maintaining results.

      community The Fear of Oral Minoxidil is Overblown

      in Research/Science  272 upvotes 9 months ago
      Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.

      community Minox 3mg, Finasteride 1.2mg (6 month perfect adherence)

      in Progress Pictures  368 upvotes 4 days ago
      Significant hair improvement was achieved using 3mg Minoxidil and 1.2mg Finasteride over six months, with no side effects, leading to reconsideration of a hair transplant. A detailed skincare routine, including tretinoin and SPF, also improved skin appearance.

      community 4 months topical minoxidil + 2 months finasteride

      in Minoxidil  132 upvotes 1 year ago
      Topical minoxidil and oral finasteride are effectively promoting hair growth with minimal side effects, such as no impact on sex drive. Users report positive results and reduced hair shedding, with some using a combination of topical foam containing both minoxidil and finasteride.

      community 22m hormone test - 4months fin, test 3 weeks off fin.

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      A 22-year-old male has been using finasteride for 4 months without major side effects but is concerned about hormone test results showing low SHBG and high estrogen. He plans to consult a doctor and is considering alternatives like minoxidil or topical finasteride to avoid health issues.

      community 18mo progress - topical fin/min + oral min/dut

      in Progress Pictures  91 upvotes 1 year ago
      The user experienced significant hair regrowth using topical finasteride/minoxidil and oral minoxidil/dutasteride, with some mild side effects that diminished over time. They plan to add microneedling to their regimen and have seen hair shedding cycles every six months, followed by thicker regrowth.

      community 12 month fin update. Long curly hair

      in Finasteride/Dutasteride  675 upvotes 1 year ago
      A user experienced significant hair regrowth after using 1mg of finasteride daily for a year, avoiding minoxidil due to its toxicity to cats. They attributed success to quitting smoking, a better diet, and reduced stress, with only watery semen as a side effect.

      community 5 month hair progress on fin+min

      in Progress Pictures  625 upvotes 1 year ago
      The user shared their 5-month hair progress using oral finasteride and minoxidil, reporting positive results with minimal side effects. They use a chewable 2-in-1 product from Hims for convenience.

      community PP405 mechanism question - looking for discussion

      in Treatment  7 upvotes 3 weeks ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Any growth (been taking iron supplements)

      in Is this regrowth? 8 months ago
      The conversation discusses hair loss treatments, focusing on iron supplements for low ferritin levels and considering finasteride and minoxidil if thinning persists. There is debate over starting with finasteride versus dutasteride, with some users advocating for dutasteride due to its potency, while others caution about potential side effects.

      community Fin, Testorone and Gyno Theory

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      The conversation discusses managing gynecomastia symptoms potentially caused by finasteride use, with treatments including reducing finasteride dosage, using DIM, ashwagandha, tamoxifen, epistane, and arimistane. Users share experiences and advice on balancing testosterone and estrogen levels to address symptoms.

      community Atleast 30 character are requireded

      in Satire  470 upvotes 1 year ago
      The conversation humorously discusses hair loss treatments, including finasteride, minoxidil, and dermarolling, with users sharing personal experiences and side effects. Some users mention changes in hair and semen consistency, while others discuss male contraception methods.

      community 5Months 0.5mg Fin + 2.5mg Oral Min | UPDATE #2

      in Progress Pictures  923 upvotes 2 years ago
      The user, Salty-Peace-577, shared their 5-month update on using 0.5mg oral finasteride and 2.5mg oral minoxidil for hair loss. They experienced significant hair growth, particularly in their eyebrows, and shared their regimen and tips for hair growth. Some users in the conversation also discussed the side effects they experienced with different dosages of the medications.

      community Topical - Dosage help (0.3% FIN per mL?)

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user is considering starting a topical treatment for hair loss, using a spray containing 0.3% finasteride, 5% minoxidil, and 0.01% tretinoin. They are questioning the dosage and considering reducing the application to achieve 0.15% finasteride and 5% minoxidil.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Fin journey update, 4 years, 1mg oral daily

      in Progress Pictures  387 upvotes 1 year ago
      The user has been using 1mg oral finasteride daily for four years, experiencing significant hair regrowth and increased testosterone levels without negative side effects. They advise patience and monitoring for side effects, noting that their hair continues to improve with this treatment.

      community [43M] 6 months topical .01%->.025% / 5% min

      in Progress Pictures  7 upvotes 1 year ago
      A 43-year-old man shares his slow progress using low-dose topical finasteride and 5% minoxidil for hair growth, along with scalp massages, microneedling, biotin supplements, and pumpkin seed oil. Another user suggests shaving and warns about potential infertility from finasteride, but the original poster remains optimistic, citing others' successful results.

      community Questions about Topical Finasteride and more

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      The conversation discusses using topical finasteride (0.25% gel) and minoxidil (5% foam) for hair loss, with users sharing experiences about application methods, microneedling, and results. Some users have switched to oral finasteride for convenience and cost-effectiveness, while others discuss the greasy nature of the topical solution.

      community Forgot min+fin whilst travelling

      in General  82 upvotes 11 months ago
      The user forgot their minoxidil and finasteride while traveling in Indonesia and is concerned about hair loss. They are advised that a 6-week break might cause some shedding but not drastic changes, and it's safer to wait for friends to bring the medication due to strict drug laws.

      community Which Pyrilutamide has worked the best for you ?

      in Treatment  5 upvotes 1 year ago
      The user is currently using Minoxidil with melatonin, rosemary, peppermint, azelaic acid, and RU58841 for hair loss and plans to add fluridil and Pyrilutamide. They seek advice on the best Pyrilutamide source, noting Actifolic worked briefly.