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Exploring hair loss treatments beyond DHT, including Minoxidil, pyruvate, Gt20029 targeting androgen receptors, and vasodilators. Other options like Kx826, adenosine signaling, growth factor topicals, and microneedling are also discussed.

Minoxidil users report dark circles and eye bags. Solutions include water pills, caffeine serum, retinol, and collagen peptides.

A user shared their 5-month progress in treating hair loss using HIMs topical finasteride and minoxidil, micro-needling with a 1.5mm needle, and RU-58841. The post includes progress pictures showing improvement from a NW7 hair loss stage.

PP405 cannot restore extracted hair follicles after a transplant as they are removed, not dormant. Combining verteporphin with wounding and PP405 is suggested but not confirmed effective.

The user shared progress pictures after using a topical treatment of 0.3% finasteride and 6% minoxidil once a day for a year, noting improvement in the front but needing suggestions for the crown. They confirmed using a product from Hims.

The conversation discusses a new hair growth treatment that showed a 14 hairs/cm2 increase in a trial, with mixed opinions on its effectiveness and potential cost. Some users are hopeful about combining it with existing treatments like oral minoxidil for better results.

The conversation is about whether stemoxydine can shorten the dormant phase after a hair transplant, known as the ugly duckling phase. There is skepticism about whether it actually works as claimed.

The user is generally happy with their hair transplant results but has concerns about graft density and placement, particularly on the left temple and hairline. They are using finasteride and minoxidil inconsistently, plan to add Priorin, and are considering microneedling and PRP sessions for future care.

User shared 9 months of progress using 1 mg finasteride and topical minoxidil, showing photos from different stages. Encouragement was given to continue the treatment.

A 28-year-old male is happy with his hair regrowth on the crown after using topical Minoxidil 5% and Finasteride 0.25% once daily, micro needling weekly, and Nizoral shampoo once a week. He has experienced no significant side effects, and his hair has become darker and thicker, with improvements in his hairline.

A user shared a 17-month update on their hair loss treatment, which included a hair transplant of 2300 grafts, using a topical solution of minoxidil and finasteride, a laser cap, and ketoconazole shampoo. They are considering another transplant and seeking honest feedback on their progress, while others share their own experiences and advice on hair loss treatments.

Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.

PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.

A 31-year-old with diffuse thinning experienced significant hair regrowth after nearly 5 months on Finasteride 0.75mg MWF. Despite initial side effects like testicle pain and reduced sex drive, these issues resolved, and positive effects included reduced nighttime urination and scalp itching.

The user has been experiencing diffuse hair thinning despite using finasteride, minoxidil, dermarolling, clobetasol cream, and PRP sessions. They seek advice on additional treatments and are advised to check vitamin D, iron, and thyroid levels.

Lab-grown hair using iPSCs is being explored, but practical applications are limited. Finasteride is suggested as the only current effective treatment.

A user shared their 5-month hair loss treatment progress using oral finasteride, Regaine foam, 2DDR serum, and microneedling, noting improvements in hair growth at the crown and front. They are considering increasing microneedling frequency or adding a shampoo to their routine.

The conversation discusses struggles with diffuse thinning and hair loss treatments, including the use of dutasteride, minoxidil, and finasteride, with limited success. The original poster regrets having a hair transplant at 21 due to weak donor hair and ongoing thinning.

The user is considering adding a topical treatment to their current regimen of finasteride and oral minoxidil to protect their temple area, with options like piro, RU58841, or topical finasteride or dutasteride. They are advised against overcomplicating their treatment, but another user suggests a topical with 8% minoxidil/dutasteride for better results.

The conversation discusses using RU58841 for hair loss, with OP experiencing thinning in the front area and steady hair loss. OP plans to try microneedling while avoiding finasteride and dutasteride.

A user named "Redbone2222" shares their positive experience with a hair transplant procedure of 2500-3000 grafts, along with the use of 1mg finasteride daily and 5% topical minoxidil. They express satisfaction with the results and believe that finasteride has been more effective for them than minoxidil.

The conversation discusses the effectiveness of adding topical caffeine serum to a hair loss treatment routine that includes minoxidil and finasteride. Users suggest alternatives like stemoxidine, alphatradiol, and pyrilutamide, noting that evidence for caffeine's effectiveness is weak.

A 23-year-old male shared his 5.5-month progress using 5% topical minoxidil foam for hair regrowth, considering adding finasteride despite concerns about side effects. Users advised starting finasteride to maintain gains, with some suggesting topical options to minimize side effects.

The user wants to try using 0.025% topical finasteride every day by diluting their 0.1% topical finasteride with alfatradiol, and is asking if it's possible to mix them or if there are other options. They heard that alfatradiol might not be suitable for this purpose.

Dr. Gabel doesn't use Verteporfin because it's not FDA approved. The user is getting FUT and wants to minimize scarring and maximize hair regrowth.

The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

A 36-year-old man shared his one-year progress using 1mg oral finasteride and 5% topical minoxidil twice daily, showing significant hair regrowth on his hairline, eyebrows, and beard. He reported no major side effects, except for some eye irritation from minoxidil application near the eyes.

New product Tomorrowlabs HSF targets hair loss through HIF pathway indirectly by removing scalp iron. Minoxidil and Stemoxydine also relate to HIF pathway.

User reported initial hair regrowth with 0.25 mg finasteride taken four times a week, experiencing a second shedding phase, and no side effects. They also mentioned using RU58841 without success and plan to stop after a year.

The conversation is about whether doctors are offering hair transplants using verteporfin. Dr. Bargouthi in Jordan and Dr. Bloxham in New York are currently conducting trials on it.