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      community Rejected for the 2nd time for the VDPHL01 Clinical Trials (believe it or not!)

      in Chat  12 upvotes 1 year ago
      The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

      community 4 Months (Fin + Duta + Minoxidil + Micro)

      in Progress Pictures  273 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen including finasteride, dutasteride, minoxidil, tretinoin, microneedling, and red light therapy. The user plans to update on progress after eight months.

      community What’s more reliable right now, pyrilutamide or RU?

      in Treatment  15 upvotes 3 years ago
      Treatments for hair loss, with the user considering Pyrilutamide and RU58841 as options. It is noted that although Pyrilutamide has been studied more and is allegedly more effective, there are doubts about its authenticity in the market. KX-826 is suggested as an alternative as it has a stronger effect than RU58841 and there is scientific research on it.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  12 upvotes 1 year ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community Got into argument with my dermatologist, AITA?

      in General  198 upvotes 4 months ago
      A 20-year-old male is frustrated with his dermatologist for refusing to prescribe DHT blockers like finasteride or dutasteride, instead pushing for a hair transplant despite ongoing hair thinning. The user feels dismissed and unreasonably treated, and is advised by another user to find a better dermatologist and consider finasteride or dutasteride for effective treatment.

      community Can RU58841 stop hairloss for a long time?

      in Research/Science  9 upvotes 2 years ago
      A user is considering using RU58841 to treat hair loss and asks if it can be effective for 4-5 years. Some suggest starting with a lower concentration and debate the safety of RU58841 compared to approved drugs like finasteride.

      community [progress] Finasteride 42 MONTHS update

      in Update  67 upvotes 3 years ago
      The user's 42 month experience using finasteride for hair loss, their opinion on minoxidil use and the potential of pyrilutamide and another Chinese drug as treatments.

      community Nest topical compound stack to fight hair loss

      in Treatment  1 upvotes 2 years ago
      The user is seeking advice for the best topical treatment to combat their ongoing hair loss, despite already using oral dutasteride, RU-58841, and minoxidil. They are considering adding CB-03-01 or topical Spiro to their regimen to lower testosterone levels at the follicles.

      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community M29 Dut/Min/Microneedle/Tretinoin

      in Is this regrowth?  25 upvotes 1 year ago
      A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.

      community 4 years progress- Minox combined with Fin

      in Progress Pictures  198 upvotes 9 months ago
      A user shared their 4-year progress using topical minoxidil and 1mg finasteride daily for hair regrowth, noting plans to reduce finasteride due to minor side effects. They emphasized consistency as key to success, with noticeable improvements in hair density and color.

      community What to look Forward to in 2025

      in Research/Science  19 upvotes 1 year ago
      Hair loss treatments are advancing, with Coegin Pharma's FOL005 expected this year and Breezula potentially later. Pyrilutamide is available but not very effective, while Kintor's products face skepticism; traditional treatments like finasteride and minoxidil remain dominant.

      community FOR PYRILUTAMIDE NON-BELIEVERS (progress album, 14 months)

      in Progress Pictures  31 upvotes 2 years ago
      A user shared their 14-month progress using Pyrilutamide and Minoxidil for hair loss, noting improvement and no side effects with these treatments, unlike their negative experiences with Finasteride and RU58841. They emphasized the importance of consistent application for seeing results.

      community Using oral min, fin, biotin for 4 months

      in Is this regrowth?  73 upvotes 6 months ago
      The user has been using oral minoxidil (5mg), finasteride (1mg), and biotin for 4 months with minimal progress in hair regrowth. Other users suggest patience, considering alternative treatments, and note that biotin may not significantly contribute unless there's a deficiency.

      community How much break from ru58841 if trying to get baby?

      in Chat  1 upvotes 1 year ago
      The user is asking about the safety of using RU58841 when trying to conceive and if others have had healthy babies after using it. They are seeking advice on how long to take a break from RU58841 before attempting to have a baby.

      community Is RU58841 worth it? Has anybody seen success on it?

      in Technology  6 upvotes 1 month ago
      RU58841 is used by some for hair loss, with mixed results; one user reported success with no side effects, while another experienced lung and heart issues. RU58841 is often sourced from third-party vendors and used alongside treatments like dutasteride and minoxidil.

      community Seeking Advice After Frustrating Dermatologist Visits: Min/Fin vs Supplements

      in General  119 upvotes 6 months ago
      The user is frustrated with dermatologists who dismiss Minoxidil and finasteride as unsafe, instead recommending mustard oil, PRP, zinc supplements, and hair products. The user feels these suggestions are ineffective and is considering starting Minoxidil and finasteride despite the dermatologists' advice.

      community Joining clinical study for Clascoterone (Breezula)

      in Research/Science  7 upvotes 1 year ago
      The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

      community What is fluridil binding affinity?

      in Treatment  4 upvotes 4 years ago
      Fluridil is hard to obtain and only available in Slovakia and Czechia, with no systemic side effects but possibly limited effectiveness compared to finasteride. The original poster is using finasteride and minoxidil without success and is considering trying fluridil despite its cost.