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      community Am I misunderstanding the medication dosage calculation?

      in Product  2 upvotes 1 year ago
      The conversation discusses confusion over the dosage calculation of a topical solution containing 0.25% finasteride, 5% minoxidil, and 0.001% tretinoin. The user considers switching to a 0.025% finasteride solution to enhance the effects of tretinoin and minoxidil.

      community Verteporfin mixing solute for transplants

      in Treatment  12 upvotes 2 years ago
      Doctors are testing verteporfin topically for healing and potential regeneration after transplants. The user is asking how it is formulated for topical use, such as if it's mixed with a carrier gel.

      community OFFICIAL Multi-Center Verteporfin Trial Recruitment

      in Research/Science  251 upvotes 1 year ago
      Recruitment for a verteporfin trial and a separate hair cloning trial using verteporfin and other methods is underway, with locations in Jordan, NYC, Beverly Hills, and Memphis. Dr. Bloxham is conducting the hair cloning trial, and interested participants are encouraged to contact him directly.

      community how to make homemade topical finasteride?

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      The conversation is about making homemade topical finasteride, discussing mixing it with Kirkland minoxidil and creating a solvent with alcohol, glycerin, and water. A formula suggestion includes 50% ethyl alcohol, 25% propylene glycol, and 25% distilled water.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 2 years ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 3 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.
      6 Months of 0.3 Fin 5% Min, Thinning More on One Side Now

      community 6 Months of 0.3 Fin 5% Min, Thinning More on One Side Now

      in General  68 upvotes 1 year ago
      The user has been using a hair solution with 0.3% finasteride and 5% minoxidil, along with microneedling, but is experiencing more thinning on one side. Suggestions include checking application techniques and ensuring microneedling is not overdone.

      community How to dose 5mg finesteride?

      in Basic Questions  48 upvotes 2 months ago
      A user is seeking advice on how to split a 5mg finasteride tablet to achieve a 1mg dose for hair loss treatment, as 1mg tablets are unavailable in Morocco. They are looking for a cost-effective solution due to financial constraints.

      community Taking small Finasteride doses

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The user has been taking small doses of Finasteride, mixed with Stemoxydine, which has helped maintain their existing hair but not regrow new hair. They're considering dissolving the Finasteride in high-alcohol content drinks for easier administration and are seeking opinions on this method.

      community a topical that combines MIN, FIN and DUT

      in Minoxidil  5 upvotes 3 years ago
      A user discusses a topical treatment combining Minoxidil, Betamethasone Valerate, Canrenone, Finasteride, and Dutasteride for hair loss. The treatment is RX-only and provided by a dermatologist.

      community bicalutamide or spironolactone for fphl

      in Female  6 upvotes 3 years ago
      Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

      community Anyone using Finastopic (no pg Isdin)?

      in Product  2 upvotes 2 years ago
      The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propylene glycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.

      community Alfatradiol 1% study rebuttal.

      in Research/Science  5 upvotes 2 years ago
      Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.

      community Predicted Breezula format? (liquid/cream/foam etc)

      in Treatment  10 upvotes 6 years ago
      The conversation is about the potential format of Breezula, a hair loss treatment, and concerns that it might be greasy or sticky. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.